Crohn Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2012-08-23Clinical Trial Update: Single Ascending Dose Study of Oral CPSI-2364 (Semapimod) [Phase 1]
This update reports completion of a Phase 1 single ascending dose study of CPSI-2364 (semmapimod) in Crohn's disease.
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CLINICAL_TRIALS trial_result · 2012-08-23Clinical Trial Update: CNI-1493 for Treatment of Moderate to Severe Crohn's Disease [Phase 2]
A Phase 2 trial of CNI-1493 for moderate to severe Crohn's disease has been terminated.
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CLINICAL_TRIALS trial_result · 2012-08-09Clinical Trial Update: Expression of TIM-3 and Correlation With Disease Activity in Pediatric Crohn's Disease With Anti TNF-α Therapy [Phase 3]
Phase 3 trial updating TIM-3 expression and its relationship to disease activity in pediatric Crohn's disease patients treated with anti-TNF…
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CLINICAL_TRIALS trial_result · 2012-08-03Clinical Trial Update: Immunological Consequences of CARD15/NOD2 Mutations in Crohn's Disease [NA]
A completed clinical trial examines the immunological consequences of CARD15/NOD2 mutations in Crohn's disease. The findings aim to improve …
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CLINICAL_TRIALS trial_result · 2012-07-27Clinical Trial Update: A Study of Safety and Effectiveness of Ustekinumab in Patients With Moderate to Severe Active Crohn's Disease Who Have Been Previously Treated With Anti-TNF Therapy [Phase 2]
Phase 2 study evaluating the safety and effectiveness of ustekinumab in patients with moderate-to-severe Crohn's disease who had prior anti-…
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CLINICAL_TRIALS trial_result · 2012-07-26Clinical Trial Update: An Audit of Patients With Crohn's Disease Treated With Infliximab (P06066)
This ClinicalTrials.gov audit reports results from Crohn's disease patients treated with infliximab. The sponsor was Merck Sharp & Dohme LLC…
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CLINICAL_TRIALS trial_result · 2012-06-27Clinical Trial Update: Adalimumab for the Management of Post-operative Crohn's Disease (CD) [Phase 3]
A Phase 3 trial is assessing adalimumab for managing post-operative Crohn's disease, with the trial status currently unknown.
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CLINICAL_TRIALS trial_result · 2012-06-26Clinical Trial Update: Preventing Postoperative Relapse in Crohn's Disease Patients at Risk: Azathioprine Versus Mesalazine [Phase 3]
Phase 3 randomized trial comparing azathioprine versus mesalazine to prevent postoperative relapse in Crohn's disease has completed. The spo…
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CLINICAL_TRIALS trial_result · 2012-06-14Clinical Trial Update: Study to Determine Relationship Between Serum Infliximab and Efficacy in Luminal Crohn's Disease Patients
Completed study assessing the relationship between serum infliximab levels and efficacy in patients with luminal Crohn's disease.
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CLINICAL_TRIALS trial_result · 2012-05-31Clinical Trial Update: Study of Nitazoxanide Tablets in the Treatment of Mild to Moderate Active Crohn's Disease [Phase 2]
A Phase 2 trial evaluating nitazoxanide tablets for mild to moderate active Crohn's disease was terminated.
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CLINICAL_TRIALS trial_result · 2012-05-16Clinical Trial Update: Evaluation of Capsule Endoscopy in Patients With Suspected Crohn's Disease [NA]
A completed clinical trial evaluating capsule endoscopy for suspected Crohn's disease; results posted in 2012.
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CLINICAL_TRIALS trial_result · 2012-04-17Clinical Trial Update: Endoscopic Severity Score of Small Bowel Crohn's Disease With Wireless Capsule Endoscopy
Clinical trial update noting completion of a study assessing endoscopic severity scoring for small bowel Crohn's disease using wireless caps…
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CLINICAL_TRIALS trial_result · 2012-04-17Clinical Trial Update: Adalimumab in Combination With Ciprofloxacin/Placebo Treatment of Perianal Fistulas in Crohn's [Phase 3]
The document reports the completion of a Phase 3 trial evaluating adalimumab in combination with ciprofloxacin for treatment of perianal fis…
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CLINICAL_TRIALS trial_result · 2012-04-04Clinical Trial Update: Efficacy and Safety of Two Regimens of Maintenance Therapy in Children With Crohn Disease [Phase 3]
Phase 3 study evaluating two maintenance therapy regimens for children with Crohn's disease. Efficacy and safety results have not yet been d…
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CLINICAL_TRIALS trial_result · 2012-03-15Clinical Trial Update: Safety and Efficacy Study of Autologous Cultured Adipose -Derived Stem Cells for the Crohn's Fistula [Phase 2]
Phase 2 clinical trial evaluating autologous cultured adipose-derived stem cells for Crohn's fistula has completed. The study reports safety…
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CLINICAL_TRIALS trial_result · 2012-03-13Clinical Trial Update: A Humanized Anti-Interferon-γ Monoclonal Antibody (HuZAF) for Moderate to Severe Crohn's Disease [Phase 2]
Phase 2 clinical study of HuZAF, a humanized anti-Interferon-γ monoclonal antibody, for moderate-to-severe Crohn's disease has completed.
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CLINICAL_TRIALS trial_result · 2012-03-12Clinical Trial Update: A Study With Pentasa in Patients With Active Crohn's Disease [Phase 3]
A Phase 3 trial of Pentasa in active Crohn's disease was terminated, with results posted in 2012.
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CLINICAL_TRIALS trial_result · 2012-03-12Clinical Trial Update: The Effect on Mucosal Healing With Pentasa Sachet in Mild to Moderate Active "Drug: Crohn's Disease" [Phase 3]
A Phase 3 trial of Pentasa Sachet (mesalamine) for mucosal healing in mild-to-moderate Crohn's disease was terminated.
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CLINICAL_TRIALS trial_result · 2012-03-08Clinical Trial Update: The Effect of a Probiotic Preparation (VSL#3) Plus Infliximab in Children With Crohn's Disease [Phase 3]
Phase 3 clinical trial evaluating VSL#3 probiotic plus infliximab in children with Crohn's disease; the current study status is unknown.
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CLINICAL_TRIALS trial_result · 2012-03-07Clinical Trial Update: Visilizumab for Moderate to Severe Inflammatory, Nonstricturing, Nonpenetrating Crohn's Disease [Phase 2]
A Phase 2 trial of visilizumab for moderate to severe inflammatory, nonstricturing Crohn's disease has completed.
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CLINICAL_TRIALS trial_result · 2012-03-07Clinical Trial Update: Visilizumab for Treatment of Perianal Fistulas in Crohn's Disease [Phase 2]
This is a completed Phase 2 clinical trial evaluating visilizumab for treatment of perianal fistulas in Crohn's disease.
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CLINICAL_TRIALS trial_result · 2012-02-24Clinical Trial Update: Efficacy and Safety Study of D9421-C 9 mg and 15 mg Versus Placebo in Japanese Patients With Active Crohn's Disease [Phase 2]
Phase 2 study evaluating D9421-C at 9 mg and 15 mg versus placebo in Japanese patients with active Crohn's disease; efficacy and safety resu…
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CLINICAL_TRIALS trial_result · 2012-02-14Clinical Trial Update: Vitamin D in Pediatric Crohn's Disease [Phase 4]
Phase 4 trial evaluating Vitamin D supplementation in pediatric Crohn's disease has completed.
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CLINICAL_TRIALS trial_result · 2012-02-01Clinical Trial Update: Remicade Safety Line (Crohn's Disease)(Study P03288)(COMPLETED)
This entry reports the completion of Crohn's disease study P03288 for Remicade (infliximab), with results posted in February 2012.
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CLINICAL_TRIALS trial_result · 2012-01-26Clinical Trial Update: Allogenic Stem Cells Derived From Lipoaspirates for the Treatment of Recto-vaginal Fistulas Associated to Crohn's Disease (ALOREVA) [Phase 1, Phase 2]
Completed Phase 1/2 clinical trial evaluating allogenic stem cells derived from lipoaspirates for treating rectovaginal fistulas in Crohn's …