Crohn Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-06-10Clinical Trial Update: Efficacy and Safety Comparison of Upadacitinib and Vedolizumab in Second-line Treatment for Crohn's Disease
A completed clinical trial comparing upadacitinib versus vedolizumab for second-line Crohn's disease to assess their efficacy and safety, as…
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CLINICAL_TRIALS trial_result · 2024-06-07Clinical Trial Update: Real-life Use of the Crohn's Disease Exclusion Diet (CDED) in Adult Patients With Crohn's Disease [NA]
This completed clinical trial evaluates the real-world use of the Crohn's Disease Exclusion Diet (CDED) in adults with Crohn's disease. The …
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CLINICAL_TRIALS trial_result · 2024-06-03Clinical Trial Update: Intra-erythrocyte Dexamethasone Versus Placebo in Patients With Steroid-dependent Crohn's Disease [Phase 3]
A Phase 3 trial comparing intra-erythrocyte dexamethasone to placebo in steroid-dependent Crohn's disease was terminated, with results poste…
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CLINICAL_TRIALS trial_result · 2024-06-03Clinical Trial Update: CD INFORM: Investigating Natalizumab Through Further Observational Research and Monitoring
The CD INFORM observational study of natalizumab for Crohn's disease has been terminated, ending further observational research and monitori…
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CLINICAL_TRIALS trial_result · 2024-05-30Clinical Trial Update: A Study to Observe Vedolizumab and Anti-tumour Necrosis Factors (Anti-TNFs) Outcomes in Real-world Biologic Ulcerative Colitis (UC) and Crohn's Disease (CD) Participants
A completed real-world observational study evaluating vedolizumab and anti-TNF therapies in patients with ulcerative colitis or Crohn's dise…
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CLINICAL_TRIALS trial_result · 2024-05-30Clinical Trial Update: Evaluation of the Response of Itraconazole and Terbinafine Therapy in Subjects With Crohn's Disease [Phase 2]
A Phase 2 trial evaluating itraconazole and terbinafine for Crohn's disease has been terminated. The update notes the study status but does …
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CLINICAL_TRIALS trial_result · 2024-05-20Clinical Trial Update: The PRognostic Effect of Environmental Factors in Crohn's and Colitis
This clinical trial evaluated the prognostic impact of environmental factors on inflammatory bowel diseases, specifically Crohn's disease an…
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CLINICAL_TRIALS trial_result · 2024-05-20Clinical Trial Update: Prebiotics and Diet to Reduce "Leaky" Gut in First Degree Relatives of Crohn's Disease Patients [NA]
Completed clinical trial assessing whether prebiotics and dietary changes can reduce gut permeability in healthy first-degree relatives of C…
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CLINICAL_TRIALS trial_result · 2024-05-10Clinical Trial Update: A Study Using Artificial Intelligence to Identify Adults With Complex Perianal Fistulas Associated With Crohn's Disease
Takeda-sponsored clinical trial used artificial intelligence to identify adults with complex perianal fistulas associated with Crohn's disea…
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CLINICAL_TRIALS trial_result · 2024-05-02Clinical Trial Update: Prospective Evaluation of a Scoring System in Patients Newly Diagnosed With Crohn's Disease
A completed prospective evaluation of a scoring system for patients newly diagnosed with Crohn's disease, sponsored by Ferring Pharmaceutica…
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CLINICAL_TRIALS trial_result · 2024-04-17Clinical Trial Update: A Phase 2a Study to Evaluate the Safety, Tolerability and Efficacy of Cannabidiol as a Steroid-sparing Therapy in Steroid-dependent Crohn's Disease Patients [Phase 2]
Phase 2a study evaluating cannabidiol as a steroid-sparing therapy in steroid-dependent Crohn's disease has completed.
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CLINICAL_TRIALS trial_result · 2024-03-29Clinical Trial Update: A Study to Evaluate Disease Control and Treatment Pattern in Participants With Moderate to Severe Inflammatory Bowel Disease (IBD) in Real Life Practice
A real-life practice study evaluating disease control and treatment patterns in moderate to severe inflammatory bowel disease, completed wit…
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CLINICAL_TRIALS trial_result · 2024-03-19Clinical Trial Update: Is Local Injection of Mesenchymal Stem Cells After Endoscopic Dilation Safe and Does it Improve the Outcome of Intestinal Stricture in Patients With Crohn's Disease? [Phase 2]
Phase 2 clinical trial investigating local injection of mesenchymal stem cells after endoscopic dilation for Crohn's disease-related intesti…
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CLINICAL_TRIALS trial_result · 2024-03-15Clinical Trial Update: Study of Relationship Between Vedolizumab Therapeutic Drug Monitoring, Biomarkers of Inflammation and Clinical Outcomes
A completed clinical trial evaluating the relationship between vedolizumab therapeutic drug monitoring, inflammation biomarkers, and clinica…
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CLINICAL_TRIALS trial_result · 2024-03-12Clinical Trial Update: Fluorescence Imaging of Adalimumab-680LT in Inflammatory Bowel Disease [Phase 1, Phase 2]
Clinical trial update on fluorescence imaging of adalimumab-680LT in inflammatory bowel disease (Crohn's disease and ulcerative colitis) acr…
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CLINICAL_TRIALS trial_result · 2024-03-05Clinical Trial Update: Top-down Infliximab Study in Kids With Crohn's Disease [Phase 4]
Phase 4 clinical trial update for top-down infliximab in pediatric Crohn's disease has completed.
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CLINICAL_TRIALS trial_result · 2024-02-26Clinical Trial Update: Evaluation of the Safety, Tolerability, and Efficacy of MDGN-002 in Adults With Moderate to Severe Active Crohn's Disease or Ulcerative Colitis [Phase 1]
Phase 1 trial evaluating MDGN-002 in adults with Crohn's disease or ulcerative colitis has been terminated.
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CLINICAL_TRIALS trial_result · 2024-02-16Clinical Trial Update: A Study Testing How BI 655130 Works in Patients With Fistulizing Crohn's Disease [Phase 2]
This Phase 2 trial of BI 655130 for fistulizing Crohn's disease has completed, with results posted on February 16, 2024.
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CLINICAL_TRIALS trial_result · 2024-01-30Clinical Trial Update: Extracorporeal Photopheresis of Patients With Crohn's Disease Using 5-aminolevulinic Acid [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating extracorporeal photopheresis with 5-aminolevulinic acid for Crohn's disease has completed recruitment.
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CLINICAL_TRIALS trial_result · 2023-12-18Clinical Trial Update: Filgotinib in the Induction and Maintenance of Remission in Adults With Moderately to Severely Active Crohn's Disease [Phase 3]
Phase 3 trial evaluating filgotinib for induction and maintenance of remission in adults with moderately to severely active Crohn's disease …
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CLINICAL_TRIALS trial_result · 2023-12-07Clinical Trial Update: Transversus Abdominis Plane Blocks With and Without Dexamethasone [Phase 1, Phase 2]
A clinical trial update on transversus abdominis plane blocks with and without dexamethasone across Phase 1 and Phase 2 stages, with unclear…
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CLINICAL_TRIALS trial_result · 2023-12-06Clinical Trial Update: Study to Evaluate the Testicular Safety of Filgotinib in Adult Males With Moderately to Severely Active Inflammatory Bowel Disease [Phase 2]
A Phase 2 study evaluating the testicular safety of filgotinib in adult males with inflammatory bowel disease was terminated; results have b…
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CLINICAL_TRIALS trial_result · 2023-12-04Clinical Trial Update: Efficacy and Safety of Oral BT-11 in Moderate to Severe Crohn's Disease [Phase 2]
Phase 2 trial of oral BT-11 in moderate to severe Crohn's disease was terminated; results posted in 2023.
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CLINICAL_TRIALS trial_result · 2023-11-27Clinical Trial Update: Therapeutic Optimization Study Based on MR Enterocolonography in Patients With Crohn's Disease [Phase 3]
Phase 3 clinical trial update on therapeutic optimization using MR enterocolonography in Crohn's disease.
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CLINICAL_TRIALS trial_result · 2023-11-21Clinical Trial Update: An Active and Placebo-Controlled Study of Brazikumab in Participants With Moderately to Severely Active Crohn's Disease [Phase 2, Phase 3]
A clinical trial update indicates Brazikumab in moderately to severely active Crohn's disease (IBD) was terminated in a combined Phase 2/Pha…