Crohn Disease
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CLINICAL_TRIALS research · 2017-08-03Clinical Trial Update: Long Term Observational Study of a Vagal Nerve Stimulation Device in Crohn's Disease [Phase 1, Phase 2]
A long-term observational study of a vagal nerve stimulation device for Crohn's disease is being conducted. The current status of the study …
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CLINICAL_TRIALS research · 2017-08-03Clinical Trial Update: Vagus Nerve Stimulation in Crohn's Disease [NA]
A clinical trial update describes a study evaluating vagus nerve stimulation for Crohn's disease conducted by SetPoint Medical, with the cur…
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CLINICAL_TRIALS research · 2017-07-19Clinical Trial Update: Individualized Infiximab Dosing-Proof of Concept Study
A clinical trial update for a proof-of-concept study on individualized dosing of infliximab in inflammatory bowel diseases. The sponsor is C…
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CLINICAL_TRIALS research · 2017-07-19Clinical Trial Update: The Role of Small Bowel Ultrasound in Initiation of Infliximab in Crohn's Disease Patients
This update covers a clinical trial examining whether small bowel ultrasound can inform the initiation of infliximab therapy in Crohn's dise…
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CLINICAL_TRIALS research · 2017-06-20Clinical Trial Update: Biodegradable Stenting Anastomoses Versus Double-layer Hand Sutures for Reconstruction in Intestinal Anastomosis [Phase 1]
Clinical trial update comparing biodegradable stenting anastomoses to double-layer hand sutures for reconstruction in intestinal anastomosis…
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CLINICAL_TRIALS research · 2017-06-08Clinical Trial Update: Comparison of Partial and Exclusive Enteral Nutrition in the Treatment of Active Childhood-onset Crohn's Disease [NA]
A trial update evaluating partial versus exclusive enteral nutrition in active childhood-onset Crohn's disease; current status is unknown.
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CLINICAL_TRIALS research · 2017-05-12Clinical Trial Update: Surgically Resected Crohn's Disease Patients: Prognostic Factors for Re-operation and New Score Building
A clinical trial update focusing on prognostic factors for re-operation after surgical resection in Crohn's disease. It also describes the d…
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CLINICAL_TRIALS research · 2017-05-09Clinical Trial Update: Resting Energy Expenditure Evaluation in Subjects With Crohn's Disease
A clinical trial update evaluating resting energy expenditure in subjects with Crohn's disease.
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CLINICAL_TRIALS research · 2017-05-02Clinical Trial Update: Urinary Prostaglandin E Metabolite (PGE-M), A Metabolite of Prostaglandin E2 (PGE2): A Novel Biomarker of Crohn's Disease Activity [NA]
The update discusses urinary PGE-M as a novel biomarker for Crohn's disease activity, based on a completed trial.
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CLINICAL_TRIALS research · 2017-02-23Clinical Trial Update: Lipid Mediators in Colonic Biopsies as Biomarkers of Disease Activity of Inflammatory Bowel Diseases [NA]
This clinical trial completed and investigated lipid mediators in colonic biopsies as biomarkers of disease activity in inflammatory bowel d…
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CLINICAL_TRIALS research · 2017-02-17Clinical Trial Update: The Role of MSC in the Treatment of Fistulas in Patients With Perianal Crohn's Disease [Phase 2, Phase 3]
This clinical trial update describes a Phase 2/Phase 3 study evaluating mesenchymal stem cell therapy for fistulas in patients with perianal…
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CLINICAL_TRIALS research · 2017-02-16Clinical Trial Update: The Impact of 6MP Metabolite Levels on Infliximab Pharmacokinetics and Anti-infliximab Antibodies in Crohn's Disease
This clinical trial update examines how 6-MP metabolite levels affect infliximab pharmacokinetics and the development of anti-infliximab ant…
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CLINICAL_TRIALS research · 2017-02-15Clinical Trial Update: Validation of the French Version of the Inflammatory Bowel Disease Questionnaire (IBDQ) for Ulcerative Colitis and Crohn's Disease
This study reports the validation of the French version of the Inflammatory Bowel Disease Questionnaire (IBDQ) for patients with Ulcerative …
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CLINICAL_TRIALS research · 2017-02-15Clinical Trial Update: Surgical Prevention of Anastomotic Recurrence by Excluding Mesentery in Crohn's Disease [NA]
This clinical trial investigates whether excluding the mesentery during surgical intervention reduces anastomotic recurrence in Crohn's dise…
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CLINICAL_TRIALS research · 2016-12-28Clinical Trial Update: Zurich Fistula Cohort Study
This document is a clinical trial update for the Zurich fistula cohort study (NCT03003351). It lists several fistula-related conditions bein…
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CLINICAL_TRIALS research · 2016-12-06Clinical Trial Update: Anti-TNF-alpha Trough Level Measurements in Inflammatory Bowel Disease
A completed clinical trial from Oslo University Hospital investigated trough levels of anti-TNF-alpha therapies in inflammatory bowel diseas…
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CLINICAL_TRIALS research · 2016-10-26Clinical Trial Update: Clinical Course of Korean Crohn's Disease Cohort
Clinical trial update describing the clinical course of Crohn's disease within a Korean cohort.
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CLINICAL_TRIALS research · 2016-10-24Clinical Trial Update: RED-FLAGS Index Validation in Crohn's Disease Patients
This entry provides an update on the RED-FLAGS Index validation study in Crohn's disease patients, sponsored by Istituto Clinico Humanitas. …
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CLINICAL_TRIALS research · 2016-08-25Clinical Trial Update: Genomic/Epigenomic Biomarkers of Deregulation of Immune System in Inflammatory Bowel Diseases
The update describes a study examining genomic and epigenomic biomarkers of immune system deregulation in Crohn's disease; the current statu…
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CLINICAL_TRIALS research · 2016-08-23Clinical Trial Update: Initial Experience With a Novel Single-Balloon Enteroscopy System in Children With IBD [NA]
Clinical trial update describing initial experience using a novel single-balloon enteroscopy system in children with inflammatory bowel dise…
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CLINICAL_TRIALS research · 2016-08-08Clinical Trial Update: The Effect of Diet on Microbial Profile and Disease Outcomes in Patients With Inflammatory Bowel Diseases [NA]
This entry reports a clinical trial evaluating whether dietary modification can alter the gut microbiome and disease outcomes in patients wi…
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CLINICAL_TRIALS research · 2016-07-07Clinical Trial Update: Mediterranean Diet as an add-on Therapy for Induction of Remission in Patients With Active Crohn's Disease [NA]
This clinical trial update outlines a study evaluating whether a Mediterranean diet used as an add-on therapy can induce remission in patien…
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CLINICAL_TRIALS research · 2016-05-12Clinical Trial Update: Thrombin Generation in Crohn's Disease
The document provides an update on a clinical trial examining thrombin generation in Crohn's disease. The study (NCT02445690) is sponsored b…
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CLINICAL_TRIALS research · 2016-04-28Clinical Trial Update: Early Surgery Versus Conservative Treatment in Patients With Ileocaecal Crohn's Disease [NA]
A clinical trial comparing early surgery to conservative treatment for ileocecal Crohn's disease is ongoing; the status is currently unknown…
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CLINICAL_TRIALS research · 2016-03-16Clinical Trial Update: IBDSL Biobank Project. Molecular Markers for Diagnosis and Therapy Response in IBD.
This update describes the IBDSL Biobank Project, which investigates molecular markers for diagnosing inflammatory bowel disease and predicti…