Crohn Disease
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON) [Phase 3]
This is a Phase 3 master protocol study (SHINE-ON) evaluating Mirikizumab (LY3074828) in pediatric participants with Ulcerative colitis or C…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: A Phase 2 Study to Evaluate MORF-057 in Adults With Moderately to Severely Active Crohn's Disease [Phase 2]
A Phase 2 clinical trial evaluating MORF-057 in adults with moderately to severely active Crohn's disease is currently recruiting, sponsored…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: A Study of Vedolizumab in Children With Ulcerative Colitis (UC) or Crohn's Disease (CD) [Phase 3]
This is a Phase 3 clinical trial evaluating vedolizumab in children with ulcerative colitis or Crohn's disease; recruitment is currently ong…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: MeSenteric SpAring Versus High Ligation Ileocolic Resection for the Prevention of REcurrent Crohn's DiseaSe (SPARES) [NA]
A clinical trial evaluating mesenteric-sparing versus high ligation ileocolic resection for preventing Crohn's disease recurrence has been t…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: Ketogenic and Carnivore (Lion) Diets for Inflammatory Bowel Disease and Rheumatoid Arthritis [NA]
A clinical trial is examining ketogenic and carnivore diets for inflammatory bowel disease and rheumatoid arthritis, and the study is curren…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Immunological Characteristics of Preclinical IBD
This clinical trial update describes a preclinical study examining the immunological characteristics of inflammatory bowel disease, includin…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: A Study to Assess Real-world Outcomes for Long-Term Use of Guselkumab
This entry describes a real-world outcomes study evaluating long-term guselkumab use in inflammatory bowel diseases, focusing on ulcerative …
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Fecal Microbiome Transplant [Phase 1]
This is a Phase 1 clinical trial update on fecal microbiome transplantation that is currently enrolling by invitation for patients with Clos…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Repetitive Transcranial Magnetic Stimulation Combined With Anti-inflammatory Diet in Crohn's Disease [NA]
This is a clinical trial investigating the combination of repetitive transcranial magnetic stimulation (rTMS) with an anti-inflammatory diet…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: An Observational, Multicenter Study to Evaluate the Effectiveness of Guselkumab for the Treatment of Participants With Crohn's Disease After Surgical Resection
An observational multicenter study to evaluate the effectiveness of guselkumab for Crohn's disease after surgical resection; the study statu…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Digestive Evolution of Children With Crohn's Disease or Ulcerative Colitis Whose Anti-TNFα Treatment Was Switched to Ustekinumab Due to Paradoxical Psoriasis,
A pediatric clinical trial evaluating outcomes for children with Crohn's disease or ulcerative colitis after switching from anti-TNF therapy…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Study Comparing Intravenous (IV)/Subcutaneous (SC) Risankizumab to IV/SC Ustekinumab to Assess Change in Crohn's Disease Activity Index (CDAI) in Adult Participants With Moderate to Severe Crohn's Disease (CD) [Phase 3]
Phase 3 study comparing IV/SC risankizumab to IV/SC ustekinumab to evaluate changes in CDAI in adults with moderate-to-severe Crohn's diseas…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study of Guselkumab in Pediatric Participants With Moderately to Severely Active Crohn's Disease [Phase 3]
Phase 3 pediatric trial evaluating guselkumab for moderately to severely active Crohn's disease is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study to Assess the Long-Term Safety of Ustekinumab Versus Other Biologics in Patients With Crohn's Disease and Ulcerative Colitis
A clinical trial is assessing the long-term safety of ustekinumab compared with other biologics in patients with Crohn's disease and ulcerat…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Biologics and Paediatric Enteral Nutrition in Crohn's Disease Study [NA]
The University of Glasgow is conducting a trial in pediatric Crohn's disease to evaluate biologics and paediatric enteral nutrition, current…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Database Study of Disease, Treatment Patterns and Healthcare Use in Children With Inflammatory Bowel Diseases in Korea
This document reports on an observational database study in Korea examining disease patterns, treatment approaches, and healthcare utilizati…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Long-term Extension (LTE) Study of Guselkumab in Pediatric Participants [Phase 3]
A long-term extension study of guselkumab in pediatric participants with Crohn's disease, ulcerative colitis, psoriatic arthritis, and juven…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease [Phase 3]
A Roche-sponsored Phase 3 trial update announcing induction therapy with Afimkibart (RO7790121) for moderately to severely active Crohn's di…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study to Evaluate the Efficacy of Guselkumab in Chinese Participants With Crohn's Disease (CD) [Phase 4]
A Phase 4 study evaluating the efficacy of guselkumab in Chinese participants with Crohn's disease is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study of Guselkumab Versus Risankizumab in Participants With Moderately to Severely Active Crohn's Disease [Phase 3]
A Phase 3 study comparing guselkumab to risankizumab in participants with moderately to severely active Crohn's disease; the trial status is…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Acupuncture Reduces Relapse in Patients With Crohn's Disease: a Superiority Trial [NA]
This clinical trial update notes an ongoing superiority trial investigating acupuncture to reduce relapse in Crohn's disease.
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Transmural Healing and Disease-Modifying Effect of Guselkumab in Crohn's Disease Patients [Phase 3]
A Phase 3 clinical trial is recruiting to evaluate the transmural healing and disease-modifying effects of guselkumab in Crohn's disease.
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Crohn's Disease [Phase 2]
A Phase 2 clinical trial is evaluating the safety of TAK-279 and its potential to reduce bowel inflammation in participants with moderately …
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study to Generate Real-world Evidence of Guselkumab Effectiveness in Inflammatory Bowel Disease in Germany
This clinical trial aims to generate real-world evidence on the effectiveness of guselkumab in treating inflammatory bowel disease, includin…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Early vs Delayed Surgery for Stricturing CD--a RCT [NA]
A randomized controlled trial comparing early versus delayed surgery for Crohn's disease with a stricturing phenotype is currently recruitin…