Crohn Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-06-08Clinical Trial Update: A Double-Blind, Randomized, Placebo-Controlled Phase II Clinical Trial to Evaluate the Safety and Efficacy of L2-01 in Subjects With Crohn's Disease [Phase 2]
Phase II trial protocol evaluating safety and efficacy of L2-01 versus placebo in Crohn's disease; the study is not yet recruiting.
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CLINICAL_TRIALS research · 2025-06-03Clinical Trial Update: A Study of Vedolizumab With and Without Upadacitinib in Adults With Crohn's Disease [Phase 3]
This is a Phase 3 clinical trial evaluating vedolizumab with and without upadacitinib in adults with Crohn's disease; the study is currently…
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CLINICAL_TRIALS research · 2025-05-31Clinical Trial Update: Spondylo-arthritis Screening Tool Among Patient Suffering From Inflammatory Bowel Disease
This clinical trial update describes the development of a screening tool to identify spondyloarthritis in patients with inflammatory bowel d…
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CLINICAL_TRIALS research · 2025-05-31Clinical Trial Update: Dietary Modification In Inflammatory Bowel Disease Patients [NA]
A dietary modification study in Crohn's disease patients is currently recruiting. The protocol focuses on diet rather than pharmacologic the…
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CLINICAL_TRIALS research · 2025-05-30Clinical Trial Update: ROLL'YN-UST: an Observational Study in Patients Treated by Steqeyma®, an Ustekinumab Biosimilar
An observational study evaluating Steqeyma, a biosimilar of ustekinumab, in patients with Crohn's disease and plaque psoriasis; recruitment …
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CLINICAL_TRIALS research · 2025-05-30Clinical Trial Update: Threonine Requirement in Adult Males With Crohn's Disease Using IAAO [NA]
A clinical trial is recruiting adult males with Crohn's disease to study threonine requirements using IAAO, sponsored by The Hospital for Si…
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CLINICAL_TRIALS research · 2025-05-29Clinical Trial Update: Efficacy and Safety of Discontinuing 5-ASA in Patients With Inflammatory Bowel Disease [NA]
This clinical trial update assesses the efficacy and safety of discontinuing 5-ASA therapy in patients with inflammatory bowel disease, incl…
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CLINICAL_TRIALS research · 2025-05-29Clinical Trial Update: Investigation of the Correlation Between Polyamine Levels and Their Key Enzymatic Activities in Association With Inflammatory Bowel Disease Progression
A clinical trial investigating whether polyamine levels and the activity of their key enzymes correlate with the progression of inflammatory…
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CLINICAL_TRIALS research · 2025-05-29Clinical Trial Update: NAZA - Nottingham/Astra ZenecA Prospective IBD Cohort Study
This clinical trial update shows a prospective inflammatory bowel disease (IBD) cohort study conducted in Nottingham is currently recruiting…
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CLINICAL_TRIALS research · 2025-05-28Clinical Trial Update: Cellvizio to Evaluate Margins in Crohn's Ileal Disease [NA]
A clinical trial update indicates that Cellvizio will be used to evaluate margins in Crohn's ileal disease, with recruitment ongoing. The st…
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CLINICAL_TRIALS research · 2025-05-28Clinical Trial Update: Comparison of Azathioprine to Methotrexate in Combination Therapy With Adalimumab in Crohn's Disease: an Open-label Randomized Controlled Trial [Phase 3]
An open-label Phase 3 trial is evaluating azathioprine versus methotrexate as part of combination therapy with adalimumab in Crohn's disease…
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CLINICAL_TRIALS research · 2025-05-25Clinical Trial Update: TDM Guided Early Optimization of ADAL in Crohn's Disease [NA]
Clinical trial NCT03261102 is evaluating therapeutic drug monitoring-guided early optimization of adalimumab in Crohn's disease. The study i…
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CLINICAL_TRIALS research · 2025-05-23Clinical Trial Update: Phase 1b/2a Trial of Allogeneic HSCT From an HLA-partially Matched Related or Unrelated Donor After TCRab+ T-cell/CD19+ B-cell Depletion for Patients With Monogenic and/or Early-onset Medically Refractory Crohn Disease [Phase 1, Phase 2]
Phase 1/2 trial evaluating allogeneic hematopoietic stem cell transplantation with TCRab+ T-cell and CD19+ B-cell depletion for monogenic or…
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CLINICAL_TRIALS research · 2025-05-23Clinical Trial Update: Small Bowel Deep Learning Algorithm Project [NA]
Clinical trial update for a small bowel deep learning algorithm project focused on Crohn disease, sponsored by London North West Healthcare …
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CLINICAL_TRIALS research · 2025-05-22Clinical Trial Update: Post-marketing Registry Study of Infliximab for Injection in Chinese Pediatric Crohn's Disease Patients [Phase 4]
A Phase 4 post-marketing registry study evaluating infliximab injections in Chinese pediatric Crohn's disease patients is currently recruiti…
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CLINICAL_TRIALS research · 2025-05-22Clinical Trial Update: Pre-stenotic Inflammation Following Endoscopic Balloon Dilatation in Crohn's Disease: A Prospective Study
A prospective study aims to assess pre-stenotic inflammation after endoscopic balloon dilatation in Crohn's disease; the trial is currently …
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CLINICAL_TRIALS research · 2025-05-20Clinical Trial Update: Stopping Aminosalicylate Therapy in Inactive Crohn's Disease [Phase 4]
A Phase 4 clinical trial is evaluating the safety and feasibility of stopping aminosalicylate therapy in patients with inactive Crohn's dise…
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CLINICAL_TRIALS research · 2025-05-16Clinical Trial Update: Effect of Acupuncture on Patients With Crohn's Disease in Remission [NA]
A clinical trial evaluating acupuncture for Crohn's disease in remission has been suspended.
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CLINICAL_TRIALS research · 2025-05-15Clinical Trial Update: Post-Operative Crohn's Disease Outcome in Children
A pediatric trial is currently recruiting to evaluate post-operative outcomes in Crohn's disease, sponsored by Schneider Children's Medical …
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CLINICAL_TRIALS research · 2025-05-14Clinical Trial Update: Effect of Acupuncture on Mild to Moderate Active Crohn's Disease [NA]
A clinical trial is evaluating acupuncture for mild to moderate active Crohn's disease and is currently recruiting.
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CLINICAL_TRIALS research · 2025-05-11Clinical Trial Update: Safety of Allogeneic Human Umbilical Cord Mesenchymal Stem Cells (UC-MSCs) to Treat Perianal Fistulas w/ Crohn's Disease [Phase 1]
This clinical trial update reports on the safety assessment of allogeneic human umbilical cord mesenchymal stem cells for treating perianal …
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CLINICAL_TRIALS research · 2025-05-09Clinical Trial Update: An Observational Study to Assess Change in Disease Activity and Adverse Events In Adult Participants With Moderate to Severe Active Crohn's Disease (CD)
This clinical trials update reports an observational study sponsored by AbbVie to assess changes in disease activity and adverse events in a…
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CLINICAL_TRIALS research · 2025-05-08Clinical Trial Update: Study of Efficacy and Adherence to Subcutaneous vs. Intravenous Vedolizumab in Patients With Inflammatory Bowel Disease Using a Novel Remote MONITORing Intervention
Clinical trial protocol comparing subcutaneous and intravenous vedolizumab for inflammatory bowel disease, incorporating a remote monitoring…
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CLINICAL_TRIALS research · 2025-05-08Clinical Trial Update: Enhancing Endoscopic Scoring Consistency and Accuracy in IBD: a Video-based Training Approach [NA]
This clinical trial update describes a video-based training approach intended to improve the consistency and accuracy of endoscopic scoring …
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CLINICAL_TRIALS research · 2025-05-07Clinical Trial Update: A Study of the Efficacy and Safety of Guselkumab in Participants With Moderately to Severely Active Crohn's Disease [Phase 2, Phase 3]
Clinical trial update for guselkumab in moderately to severely active Crohn's disease (Phase 2/3) with status ACTIVE_NOT_RECRUITING and resu…