Critical Limb Ischemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2014-10-23Clinical Trial Update: Study to Evaluate the Safety and Efficacy of JVS-100 Administered to Adults With Critical Limb Ischemia [Phase 2]
Phase 2 study evaluating JVS-100 in adults with critical limb ischemia has completed.
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CLINICAL_TRIALS trial_result · 2014-08-22Clinical Trial Update: Investigation of Safety, Pharmacokinetics and Pharmacodynamics of Different Doses of BIWH 3 in Patients With Chronic Critical Limb Ischaemia [Phase 1]
This Phase 1 study assesses safety, pharmacokinetics and pharmacodynamics of multiple doses of BIWH 3 in patients with chronic critical limb…
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CLINICAL_TRIALS trial_result · 2014-07-21Clinical Trial Update: Use of Clearway™ Balloon vs. Mechanical Thrombectomy as Initial Treatment for Acute Limb Ischemia [NA]
This clinical trial compared the Clearway Balloon catheter as initial treatment to mechanical thrombectomy for acute limb ischemia; the stud…
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CLINICAL_TRIALS research · 2014-05-23Clinical Trial Update: To Evaluate the Safety and Efficacy of IM and IV Administration of Autologous ADMSCs for Treatment of CLI [Phase 1, Phase 2]
A clinical trial update evaluating the safety and efficacy of intramuscular and intravenous autologous adipose-derived mesenchymal stromal c…
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CLINICAL_TRIALS trial_result · 2014-05-09Clinical Trial Update: Phase II Combination Stem Cell Therapy for the Treatment of Severe Leg Ischemia [Phase 2]
Phase II trial evaluating a combination stem cell therapy for critical limb ischemia and severe leg ischemia has completed.
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CLINICAL_TRIALS trial_result · 2014-04-17Clinical Trial Update: Protective Effects of L-arginine During Reperfusion by Femoropopliteal Bypass for Lower Limb Ischemic Syndrome in Humans [Phase 4]
Phase 4 clinical trial evaluating whether L-arginine protects skeletal muscle during reperfusion in femoropopliteal bypass for severe lower …
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CLINICAL_TRIALS trial_result · 2014-04-07Clinical Trial Update: A Prospective, Open, Non-randomized Phase I/II Study of Therapeutic Angiogenesis in Diabetic Patients With Critic Ischemia of Lower Limbs While Administering Positive CD133 Mobilized With G-CSF [Phase 1, Phase 2]
An open-label Phase I/II trial evaluating CD133+ cells mobilized with G-CSF for therapeutic angiogenesis in diabetic patients with critical …
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CLINICAL_TRIALS research · 2014-04-07Clinical Trial Update: Register for Patients With Diabetic Foot Syndrome and Critical Limb Ischemia
A terminated clinical trial (NCT01599442) sponsored by GWT-TUD GmbH related to type 2 diabetes mellitus with diabetic foot syndrome and crit…
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CLINICAL_TRIALS trial_result · 2014-04-07Clinical Trial Update: Safety and Efficacy Study of Urokinase for the Treatment of Diabetic Foot Syndrome and Critical Limb Ischemia [Phase 3]
A Phase 3 trial evaluating urokinase for diabetic foot syndrome and critical limb ischemia has been terminated.
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CLINICAL_TRIALS trial_result · 2014-02-03Clinical Trial Update: Efficacy and Safety of Umbilical Cord Blood Injection for Critical Limb Ischemia [Phase 1]
Phase 1 trial evaluating the efficacy and safety of umbilical cord blood injections for critical limb ischemia was terminated.
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CLINICAL_TRIALS research · 2014-01-13Clinical Trial Update: VADOplex Critical Limb Ischemia Study [Phase 2, Phase 3]
Clinical trial update for VADOplex in critical limb ischemia (Phase 2/Phase 3). The sponsor is Asklepios Kliniken Hamburg GmbH, and the curr…
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CLINICAL_TRIALS trial_result · 2013-12-18Clinical Trial Update: Study to Evaluate the Safety & Performance of the Xpert(TM) Stent in Treating Below-the-knee Lesions in Patients Undergoing Percutaneous Intervention for Chronic CLI. [Phase 1]
A Phase 1 clinical trial evaluates the safety and performance of the Xpert Stent for below-the-knee lesions in patients with chronic critica…
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CLINICAL_TRIALS trial_result · 2013-09-10Clinical Trial Update: Evaluating the Effectiveness of Paclitaxel-eluting Balloons for Below-the-knee Angioplasty in Patients With Critical Limb Ischemia
A clinical trial update assessing the effectiveness of paclitaxel-eluting balloons for below-the-knee angioplasty in patients with critical …
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CLINICAL_TRIALS trial_result · 2013-08-19Clinical Trial Update: Pilot Study of Hemospan® in Patients With Chronic Critical Limb Ischemia [Phase 2]
The Phase 2 pilot study of Hemospan in patients with chronic critical limb ischemia has completed. The trial was sponsored by Sangart.
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CLINICAL_TRIALS research · 2013-08-09Clinical Trial Update: Diabetic Foot and Vascular Progenitor Cells
Clinical trial entry evaluating diabetic foot therapy using vascular progenitor cells. The current status of the trial is unknown.
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CLINICAL_TRIALS trial_result · 2013-03-22Clinical Trial Update: Autologous Bone Marrow Stem Cell Transfer in Patients With Chronical Critical Limb Ischemia and Diabetic Foot [Phase 2]
Phase 2 clinical trial evaluating autologous bone marrow stem cell transfer in patients with chronic critical limb ischemia and diabetic foo…
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CLINICAL_TRIALS trial_result · 2013-03-07Clinical Trial Update: Study of Remodulin in Patients With Critical Limb Ischemia With No Planned Revascularization Procedures [Phase 3]
A Phase 3 trial of Remodulin (treprostinil) for critical limb ischemia without planned revascularization has been terminated.
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CLINICAL_TRIALS trial_result · 2013-03-07Clinical Trial Update: Effects of Remodulin in Patients With Critical Limb Ischemia Following a Vein Bypass Graft [Phase 2, Phase 3]
Remodulin (treprostinil) was studied in Phase 2/3 trials for critical limb ischemia after vein bypass grafts in patients with peripheral art…
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CLINICAL_TRIALS trial_result · 2013-03-05Clinical Trial Update: Mesenchymal Stem Cells in Critical Limb Ischemia [Phase 1, Phase 2]
Phase 1/2 trial evaluating mesenchymal stem cells for critical limb ischemia has completed.
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CLINICAL_TRIALS trial_result · 2013-01-29Clinical Trial Update: Drug Eluting Balloon in peripherAl inTErvention For Below The Knee Angioplasty Evaluation [Phase 4]
A Phase 4 trial evaluating a drug-eluting balloon for below-the-knee angioplasty in patients with Critical Limb Ischemia has completed.
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CLINICAL_TRIALS trial_result · 2013-01-25Clinical Trial Update: Efficacy Study of Iliac Stents to Treat TASC A-B-C-D Iliac Artery Lesions [Phase 4]
Phase 4 trial update for iliac stents to treat TASC A-D iliac artery lesions; the study status is Completed.
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CLINICAL_TRIALS trial_result · 2013-01-01Clinical Trial Update: Study to Explore the Effect of Lowering Blood Viscosity in Patients With Treatment-resistant Critical Limb Ischemia [Phase 2]
A completed Phase 2 clinical trial evaluating whether lowering blood viscosity improves outcomes in patients with treatment-resistant critic…
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CLINICAL_TRIALS research · 2012-12-24Clinical Trial Update: Optimized Strategy for Diabetic Patients With Critical Limb Ischemia(Part II) (DCLI-II) [Phase 4]
This document provides an update on the Phase 4 DCLI-II clinical trial evaluating optimized strategies for diabetic patients with critical l…
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CLINICAL_TRIALS research · 2012-12-24Clinical Trial Update: Optimized Strategy for Diabetic Patients With Critical Limb Ischemia(Part I) [Phase 4]
An update on an ongoing Phase 4 study evaluating optimized strategies for diabetic patients with critical limb ischemia (Part I).
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CLINICAL_TRIALS trial_result · 2012-12-06Clinical Trial Update: Near Infrared Spectroscopy and Transcutaneous Oxygen Pressure in Critical Limb Ischemia Before and After Treatment
This clinical trial update describes a completed study investigating near-infrared spectroscopy and transcutaneous oxygen pressure to assess…