Critical Limb Ischemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-05-18Clinical Trial Update: An Efficacy and Safety Study to Evaluate Ranger DEB for BTK Angioplasty in Patients With CLI (RANGER-BTK) [Phase 2, Phase 3]
A Phase 2/3 clinical trial evaluating Ranger DEB for below-the-knee angioplasty in patients with critical limb ischemia and peripheral arter…
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CLINICAL_TRIALS research · 2018-04-23Clinical Trial Update: Korean Multicenter Registry of ELUVIA Stent for Femoropopliteal Artery Disease (K-ELUVIA Registry)
Clinical trial update on a Korean multicenter registry evaluating the Eluvia paclitaxel-eluting stent for femoropopliteal artery disease, in…
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CLINICAL_TRIALS trial_result · 2017-10-12Clinical Trial Update: BOLD MRI as a Surrogate of Improved Muscle Oxygenation Following Endovascular Therapy for the Treatment of CLI [NA]
This update reports on a completed clinical trial evaluating BOLD MRI as a surrogate for improved muscle oxygenation following endovascular …
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CLINICAL_TRIALS research · 2017-08-04Clinical Trial Update: Allogeneic Mesenchymal Stem Cells for the Critical Limb Ischemia Therapy [Phase 1, Phase 2]
Update on a Phase 1/2 trial evaluating allogeneic mesenchymal stem cells for critical limb ischemia; current status is unknown.
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CLINICAL_TRIALS withdrawal · 2017-07-21Clinical Trial Update: Autologous Adipose-Derived Stromal Cell Delivered Via Intramuscular Injections for the Treatment of Critical Limb Ischemia [Phase 1]
A Phase 1 clinical trial evaluating autologous adipose-derived stromal cells delivered by intramuscular injections for critical limb ischemi…
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CLINICAL_TRIALS trial_result · 2017-05-09Clinical Trial Update: Monocentric Trial: Stem Cell Emergency Life Threatening Limbs Arteriopathy (SCELTA) [Phase 2, Phase 3]
The SCELTA trial, a monocentric Phase 2/3 study of stem cell therapy for critical limb ischemia, has completed.
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CLINICAL_TRIALS trial_result · 2017-05-04Clinical Trial Update: Treatment of PAD by Platelet Lysate for Therapeutic Angiogenesis [Phase 1, Phase 2]
This update reports the completion of a Phase 1/2 trial evaluating platelet lysate therapy for therapeutic angiogenesis in patients with cri…
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CLINICAL_TRIALS withdrawal · 2017-04-13Clinical Trial Update: Correlation Between FlowMet™ and Other Gold Standard Assessments in the Management of Critical Limb Ischemia (CLI) [NA]
The clinical trial investigating FlowMet in the management of critical limb ischemia has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2017-04-07Clinical Trial Update: A Clinical Trial to Study the Efficacy and Safety of Stempeucel® in Patients With CLI Due to Buergers Disease [Phase 2]
The Phase 2 trial evaluating Stempeucel for critical limb ischemia due to Buerger's disease has been withdrawn.
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CLINICAL_TRIALS research · 2017-03-17Clinical Trial Update: Use of Indocyanine Green Angiography in Critical Limb Ischemia [Phase 3]
A Phase 3 clinical trial update on using Indocyanine Green angiography in critical limb ischemia, a severe form of peripheral arterial disea…
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CLINICAL_TRIALS trial_result · 2017-02-27Clinical Trial Update: The COPPER-B Trial [NA]
The COPPER-B trial has completed enrollment/status, but this update provides no results.
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CLINICAL_TRIALS trial_result · 2017-02-23Clinical Trial Update: Evaluation of Diagnostic Criteria for Chronic Critical Limb Ischemia
A completed clinical study evaluating diagnostic criteria for chronic limb-threatening ischemia, with stroke listed among the conditions.
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CLINICAL_TRIALS trial_result · 2017-01-24Clinical Trial Update: Safety Study of Bone Marrow Cell Concentrate Prepared Using the Magellan System to Treat Critical Limb Ischemia (CLI) [Phase 1]
A completed Phase 1 safety study evaluating autologous bone marrow cell concentrate prepared with the Magellan System for treating critical …
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CLINICAL_TRIALS trial_result · 2017-01-06Clinical Trial Update: Cook Micronized Small Intestinal Submucosa (SIS) for Critical Limb Ischemia [NA]
Clinical trial status update indicating the Cook Micronized Small Intestinal Submucosa (SIS) study for critical limb ischemia has completed.
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CLINICAL_TRIALS research · 2016-12-15Clinical Trial Update: Autologous Transplantation of BM-ECs With Platelet-Rich Plasma Extract for the Treatment of Critical Limb Ischemia [Phase 1]
A Phase 1 trial evaluating autologous bone marrow endothelial cells combined with platelet-rich plasma extract for the treatment of critical…
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CLINICAL_TRIALS trial_result · 2016-12-01Clinical Trial Update: Randomized Controlled Trial on the Use of Flammacerium in Necrotic Arterial Wounds of the Lower Limb Versus Standard Treatment [Phase 2]
Phase 2 randomized trial evaluating Flammacerium for ischemic/necrotic wounds of the lower limb has been terminated; the update provides no …
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CLINICAL_TRIALS trial_result · 2016-11-08Clinical Trial Update: External Compression Therapy for Secondary Prevention of Lower-Limb Loss and Cardiovascular Mortality [NA]
Clinical trial update regarding the use of external compression therapy to prevent lower-limb loss and cardiovascular mortality in patients …
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CLINICAL_TRIALS trial_result · 2016-09-13Clinical Trial Update: A Clinical Trial to Study the Efficacy and Safety of Different Doses of Bone Marrow Derived Mesenchymal Stem Cells in Patients With Critical Limb Ischemia Due to Buergers Disease [Phase 2]
This Phase 2 clinical trial investigated different doses of bone marrow–derived mesenchymal stem cells in patients with critical limb ischem…
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CLINICAL_TRIALS trial_result · 2016-08-12Clinical Trial Update: Effectiveness and Safety of Adipose-Derived Regenerative Cells for the Treatment of Critical Lower Limb Ischemia [Phase 1, Phase 2]
This document is a clinical trial update on the use of adipose-derived regenerative cells to treat critical limb ischemia in Phase 1/2, with…
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CLINICAL_TRIALS trial_result · 2016-07-28Clinical Trial Update: Critical Limb Ischemia Rapid Delivery by SurgWerks-CLI Kit and VXP System [Phase 3]
Phase 3 clinical trial update evaluating SurgWerks-CLI Kit and VXP System for rapid delivery in critical limb ischemia. The trial status is …
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CLINICAL_TRIALS trial_result · 2016-07-18Clinical Trial Update: STREAMER : STent Restenosis And MEdicaments Release [Phase 3]
The STREAMER Phase 3 trial evaluating a drug-eluting stent for restenosis in critical limb ischemia has completed.
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CLINICAL_TRIALS trial_result · 2016-06-15Clinical Trial Update: Treatment CLI Nonrevascularizable Lower Limb With Cell Therapy [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating cell therapy for nonrevascularizable critical limb ischemia of the lower limbs. The trial status is comp…
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CLINICAL_TRIALS trial_result · 2016-05-02Clinical Trial Update: Efficacy and Safety of XRP0038/NV1FGF in Critical Limb Ischemia Patients With Skin Lesions [Phase 3]
Phase 3 trial evaluating the efficacy and safety of XRP0038/NV1FGF in patients with critical limb ischemia and skin lesions; the study is co…
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CLINICAL_TRIALS research · 2016-04-19Clinical Trial Update: Purified CD34+ Cells Versus Peripheral Blood Mononuclear Cells in Treatment of Critical Limb Ischemia [NA]
A clinical trial compares purified CD34+ cell therapy to peripheral blood mononuclear cells for treating critical limb ischemia, sponsored b…
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CLINICAL_TRIALS trial_result · 2016-03-16Clinical Trial Update: Intraarterial Infusion of Autologous Bone Marrow in Diabetic Patients With Chronic Ischemia of Lower Limbs (CLI) no Revascularization [Phase 1, Phase 2]
A Phase 1/2 trial evaluating intraarterial infusion of autologous bone marrow cells in diabetic patients with chronic limb ischemia without …