Critical Limb Ischemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2012-08-31Clinical Trial Update: Impact of Critical Limb Ischemia on Long Term Cardiac Mortality in Diabetic Patients Undergoing Percutaneous Coronary Revascularization
This completed clinical trial evaluated whether critical limb ischemia affects long-term cardiac mortality in diabetic patients undergoing p…
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CLINICAL_TRIALS trial_result · 2012-06-19Clinical Trial Update: Safety of Intramuscular Injection of Allogeneic PLX-PAD Cells for the Treatment of Critical Limb Ischemia [Phase 1]
Phase 1 trial assessing the safety of intramuscular allogeneic PLX-PAD cells for treating Critical Limb Ischemia; the report focuses on safe…
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CLINICAL_TRIALS trial_result · 2012-06-14Clinical Trial Update: Autologous Endothelial Progenitor Cells (EPCs) From Peripheral Blood in the Treatment of Critical Limb Ischemia [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating autologous endothelial progenitor cells from peripheral blood for treating critical limb ischemia has co…
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CLINICAL_TRIALS trial_result · 2012-05-25Clinical Trial Update: Induced Wound Healing by Application of Expanded Bone Marrow Stem Cells in Diabetic Patients With Critical Limb Ischemia [Phase 2]
A Phase 2 clinical trial evaluating expanded autologous bone marrow stem cells for inducing wound healing in diabetic patients with critical…
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CLINICAL_TRIALS trial_result · 2012-04-25Clinical Trial Update: Autologous Angiogenic Cell Precursors (ACPs) for the Treatment of Peripheral Artery Disease [Phase 2]
Phase 2 clinical trial of autologous angiogenic cell precursors for peripheral artery disease, including critical limb ischemia, has complet…
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CLINICAL_TRIALS trial_result · 2012-03-09Clinical Trial Update: Feasability Study of Autologous Bone Marrow Aspirate Concentrate for Treatment of CLI [Phase 1, Phase 2]
This update reports the completion of a Phase 1/2 feasibility study evaluating autologous bone marrow aspirate concentrate for treatment of …
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CLINICAL_TRIALS trial_result · 2011-10-12Clinical Trial Update: Safety and Efficacy Study of Autologous BM-MNC Processed by Two Methods for Treating Patients With Chronic Limb Ischemia [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating the safety and efficacy of autologous bone marrow mononuclear cells processed by two methods in patien…
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CLINICAL_TRIALS trial_result · 2011-08-19Clinical Trial Update: Study of Hepatocyte Growth Factor (HGF) Via Plasmid Vector to Improve Perfusion in Critical Limb Ischemia Patients With Peripheral Ischemic Ulcers [Phase 2]
Phase 2 trial evaluating hepatocyte growth factor via plasmid vector to improve perfusion in critical limb ischemia with peripheral ischemic…
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CLINICAL_TRIALS trial_result · 2011-08-08Clinical Trial Update: Balloon Angioplasty Versus Xpert Stent in CLI Patients XXS Study [Phase 4]
This is a Phase 4 clinical trial update comparing balloon angioplasty to the Xpert Stent in patients with critical limb ischemia; the study …
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CLINICAL_TRIALS trial_result · 2011-07-29Clinical Trial Update: Autologous Transplantation of Bone Marrow Mononuclear Cell (BM-MNC) With and Without Granulocyte-Colony Stimulation Factor (G-CSF) for Treatment of Chronic Lower Limb Ischemic Patients [Phase 1, Phase 2]
Completed Phase 1/Phase 2 clinical trial evaluating autologous bone marrow mononuclear cell transplantation with and without granulocyte-col…
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CLINICAL_TRIALS trial_result · 2011-07-25Clinical Trial Update: Injection of Autologous CD34-Positive Cells for Critical Limb Ischemia [Phase 1, Phase 2]
Phase 1/2 trial evaluating autologous CD34-positive cell injections for critical limb ischemia has completed, involving patients with periph…
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CLINICAL_TRIALS trial_result · 2011-04-28Clinical Trial Update: Combination Stem Cell Therapy for the Treatment of Severe Leg Ischemia [Phase 1]
Phase 1 clinical trial evaluating a combination stem cell therapy for severe leg ischemia has completed the study, with status reported as c…
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CLINICAL_TRIALS trial_result · 2011-02-21Clinical Trial Update: Feasibility of Peripheral Angioplasty in Type D TASCII Lesions
A completed clinical trial assessing the feasibility of peripheral angioplasty for Type D TASC lesions in patients with diabetes mellitus an…
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CLINICAL_TRIALS trial_result · 2010-12-02Clinical Trial Update: Drug Eluting Stents In The Critically Ischemic Lower Leg [Phase 2]
A Phase 2 clinical trial evaluating the use of drug-eluting stents for treatment of critical limb ischemia in the lower extremities has comp…
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CLINICAL_TRIALS trial_result · 2010-12-01Clinical Trial Update: Comparison of Autologous Mesenchymal Stem Cells and Mononuclear Cells on Diabetic Critical Limb Ischemia and Foot Ulcer [Phase 1]
Phase 1 trial comparing autologous mesenchymal stem cells with autologous mononuclear cells for diabetic critical limb ischemia and foot ulc…
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CLINICAL_TRIALS trial_result · 2010-12-01Clinical Trial Update: DURABILITY-200: EverFlex 200mm Long Nitinol Stents in TASC C&D Femoropopliteal Lesions [Phase 4]
Phase 4 trial update showing completion of the DURABILITY-200 study evaluating EverFlex 200 mm nitinol stents in TASC C&D femoropopliteal le…
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CLINICAL_TRIALS trial_result · 2010-10-19Clinical Trial Update: VEGF Gene Transfer for Critical Limb Ischemia [Phase 1]
A Phase 1 trial evaluating vascular endothelial growth factor (VEGF) gene transfer for critical limb ischemia has completed its study. The u…
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CLINICAL_TRIALS trial_result · 2010-10-13Clinical Trial Update: Umbilical Cord Mesenchymal Stem Cells Injection for Diabetic Foot [Phase 1, Phase 2]
This document describes a Phase 1/Phase 2 clinical trial evaluating injections of umbilical cord-derived mesenchymal stem cells for diabetic…
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CLINICAL_TRIALS trial_result · 2009-06-04Clinical Trial Update: Validation of OxyVu for Assessing Level of Amputation With Comparison to Other Modalities
This update reports on the clinical validation of the OxyVu device for determining the level of amputation, comparing its performance to oth…
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CLINICAL_TRIALS trial_result · 2009-05-14Clinical Trial Update: ALD-301 for Critical Limb Ischemia, Randomized Trial [Phase 1, Phase 2]
ALD-301 was evaluated in a randomized Phase 1/2 trial for critical limb ischemia and peripheral arterial disease. The study status is comple…
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CLINICAL_TRIALS trial_result · 2009-02-16Clinical Trial Update: Cell Therapy With Bone Marrow Mononuclear Cells in Critical Leg Ischemia (CLI) [Phase 1]
This clinical trial update describes a Phase 1 study evaluating autologous bone marrow mononuclear cell therapy for critical limb ischemia. …
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CLINICAL_TRIALS trial_result · 2008-08-20Clinical Trial Update: Plaque Removal Versus Open Bypass Surgery For Critical Limb Ischemia [Phase 4]
Phase 4 clinical trial comparing plaque removal versus open bypass surgery for critical limb ischemia has been terminated.
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CLINICAL_TRIALS trial_result · 2008-05-16Clinical Trial Update: Safety/Feasibility Study of HBOC-201 in Amputation at/Below Knee From Critical Lower Limb Ischemia [Phase 2]
Phase 2 safety/feasibility trial of HBOC-201 in below-knee amputation due to critical limb ischemia has been terminated.
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CLINICAL_TRIALS trial_result · 2008-01-11Clinical Trial Update: Study of HGF Via Plasmid Vector to Improve Perfusion in Critical Limb Ischemia [Phase 2]
A Phase 2 clinical trial of a hepatocyte growth factor (HGF) plasmid vector to improve perfusion in critical limb ischemia has completed.
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CLINICAL_TRIALS trial_result · 2007-08-31Clinical Trial Update: ACPs in Severe PAD/CLI by Direct Intramuscular Injection [Phase 1]
A Phase 1 trial evaluating ACPs delivered by direct intramuscular injection for severe peripheral arterial disease and critical limb ischemi…