Critical Limb Ischemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2015-03-09Clinical Trial Update: Drug Eluting Stents In The Critically Ischemic Lower Leg 2 [Phase 2, Phase 3]
The update indicates completion of Phase 2 and Phase 3 trials evaluating drug-eluting stents for peripheral arterial disease with critical l…
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CLINICAL_TRIALS trial_result · 2015-03-02Clinical Trial Update: Iloprost Therapy in Patients With Critical Limb Ischemia
A Bayer-sponsored clinical trial evaluating Iloprost therapy in patients with peripheral arterial disease, including those with critical lim…
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CLINICAL_TRIALS trial_result · 2015-02-09Clinical Trial Update: Self Expanding Nitinol Stent Versus Percutaneous Transluminal Arterial Angioplasty (PTA) With Optional Bailout Stenting in Case of PTA Failure in Patients With Symptomatic Critical Limb Ischemia or Severe Intermittent Claudication (EXPAND) [Phase 4]
Phase 4 trial comparing a self-expanding nitinol stent to percutaneous transluminal angioplasty with optional bailout stenting in symptomati…
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CLINICAL_TRIALS trial_result · 2014-12-05Clinical Trial Update: Safety Study of Adult Stem Cells to Treat Patients With Severe Leg Artery Disease [Phase 1]
A Phase 1 safety study of adult stem cell therapy for severe leg artery disease has been terminated.
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CLINICAL_TRIALS trial_result · 2014-11-19Clinical Trial Update: Registry of First-line Treatments in Patients With Critical Limb Ischemia
The registry study evaluating first-line treatments for patients with critical limb ischemia has completed.
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CLINICAL_TRIALS trial_result · 2014-10-27Clinical Trial Update: Study of IN.PACT Amphirion™ Drug Eluting Balloon vs. Standard PTA for the Treatment of Below the Knee Critical Limb Ischemia [NA]
Completed clinical trial comparing the IN.PACT Amphirion Drug Eluting Balloon to standard PTA for below-the-knee critical limb ischemia; res…
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CLINICAL_TRIALS trial_result · 2014-10-23Clinical Trial Update: Study to Evaluate the Safety and Efficacy of JVS-100 Administered to Adults With Critical Limb Ischemia [Phase 2]
Phase 2 study evaluating JVS-100 in adults with critical limb ischemia has completed.
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CLINICAL_TRIALS trial_result · 2014-08-22Clinical Trial Update: Investigation of Safety, Pharmacokinetics and Pharmacodynamics of Different Doses of BIWH 3 in Patients With Chronic Critical Limb Ischaemia [Phase 1]
This Phase 1 study assesses safety, pharmacokinetics and pharmacodynamics of multiple doses of BIWH 3 in patients with chronic critical limb…
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CLINICAL_TRIALS trial_result · 2014-07-21Clinical Trial Update: Use of Clearway™ Balloon vs. Mechanical Thrombectomy as Initial Treatment for Acute Limb Ischemia [NA]
This clinical trial compared the Clearway Balloon catheter as initial treatment to mechanical thrombectomy for acute limb ischemia; the stud…
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CLINICAL_TRIALS trial_result · 2014-05-09Clinical Trial Update: Phase II Combination Stem Cell Therapy for the Treatment of Severe Leg Ischemia [Phase 2]
Phase II trial evaluating a combination stem cell therapy for critical limb ischemia and severe leg ischemia has completed.
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CLINICAL_TRIALS trial_result · 2014-04-17Clinical Trial Update: Protective Effects of L-arginine During Reperfusion by Femoropopliteal Bypass for Lower Limb Ischemic Syndrome in Humans [Phase 4]
Phase 4 clinical trial evaluating whether L-arginine protects skeletal muscle during reperfusion in femoropopliteal bypass for severe lower …
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CLINICAL_TRIALS trial_result · 2014-04-07Clinical Trial Update: A Prospective, Open, Non-randomized Phase I/II Study of Therapeutic Angiogenesis in Diabetic Patients With Critic Ischemia of Lower Limbs While Administering Positive CD133 Mobilized With G-CSF [Phase 1, Phase 2]
An open-label Phase I/II trial evaluating CD133+ cells mobilized with G-CSF for therapeutic angiogenesis in diabetic patients with critical …
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CLINICAL_TRIALS trial_result · 2014-04-07Clinical Trial Update: Safety and Efficacy Study of Urokinase for the Treatment of Diabetic Foot Syndrome and Critical Limb Ischemia [Phase 3]
A Phase 3 trial evaluating urokinase for diabetic foot syndrome and critical limb ischemia has been terminated.
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CLINICAL_TRIALS trial_result · 2014-02-03Clinical Trial Update: Efficacy and Safety of Umbilical Cord Blood Injection for Critical Limb Ischemia [Phase 1]
Phase 1 trial evaluating the efficacy and safety of umbilical cord blood injections for critical limb ischemia was terminated.
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CLINICAL_TRIALS trial_result · 2013-12-18Clinical Trial Update: Study to Evaluate the Safety & Performance of the Xpert(TM) Stent in Treating Below-the-knee Lesions in Patients Undergoing Percutaneous Intervention for Chronic CLI. [Phase 1]
A Phase 1 clinical trial evaluates the safety and performance of the Xpert Stent for below-the-knee lesions in patients with chronic critica…
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CLINICAL_TRIALS trial_result · 2013-09-10Clinical Trial Update: Evaluating the Effectiveness of Paclitaxel-eluting Balloons for Below-the-knee Angioplasty in Patients With Critical Limb Ischemia
A clinical trial update assessing the effectiveness of paclitaxel-eluting balloons for below-the-knee angioplasty in patients with critical …
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CLINICAL_TRIALS trial_result · 2013-08-19Clinical Trial Update: Pilot Study of Hemospan® in Patients With Chronic Critical Limb Ischemia [Phase 2]
The Phase 2 pilot study of Hemospan in patients with chronic critical limb ischemia has completed. The trial was sponsored by Sangart.
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CLINICAL_TRIALS trial_result · 2013-03-22Clinical Trial Update: Autologous Bone Marrow Stem Cell Transfer in Patients With Chronical Critical Limb Ischemia and Diabetic Foot [Phase 2]
Phase 2 clinical trial evaluating autologous bone marrow stem cell transfer in patients with chronic critical limb ischemia and diabetic foo…
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CLINICAL_TRIALS trial_result · 2013-03-07Clinical Trial Update: Study of Remodulin in Patients With Critical Limb Ischemia With No Planned Revascularization Procedures [Phase 3]
A Phase 3 trial of Remodulin (treprostinil) for critical limb ischemia without planned revascularization has been terminated.
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CLINICAL_TRIALS trial_result · 2013-03-07Clinical Trial Update: Effects of Remodulin in Patients With Critical Limb Ischemia Following a Vein Bypass Graft [Phase 2, Phase 3]
Remodulin (treprostinil) was studied in Phase 2/3 trials for critical limb ischemia after vein bypass grafts in patients with peripheral art…
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CLINICAL_TRIALS trial_result · 2013-03-05Clinical Trial Update: Mesenchymal Stem Cells in Critical Limb Ischemia [Phase 1, Phase 2]
Phase 1/2 trial evaluating mesenchymal stem cells for critical limb ischemia has completed.
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CLINICAL_TRIALS trial_result · 2013-01-29Clinical Trial Update: Drug Eluting Balloon in peripherAl inTErvention For Below The Knee Angioplasty Evaluation [Phase 4]
A Phase 4 trial evaluating a drug-eluting balloon for below-the-knee angioplasty in patients with Critical Limb Ischemia has completed.
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CLINICAL_TRIALS trial_result · 2013-01-25Clinical Trial Update: Efficacy Study of Iliac Stents to Treat TASC A-B-C-D Iliac Artery Lesions [Phase 4]
Phase 4 trial update for iliac stents to treat TASC A-D iliac artery lesions; the study status is Completed.
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CLINICAL_TRIALS trial_result · 2013-01-01Clinical Trial Update: Study to Explore the Effect of Lowering Blood Viscosity in Patients With Treatment-resistant Critical Limb Ischemia [Phase 2]
A completed Phase 2 clinical trial evaluating whether lowering blood viscosity improves outcomes in patients with treatment-resistant critic…
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CLINICAL_TRIALS trial_result · 2012-12-06Clinical Trial Update: Near Infrared Spectroscopy and Transcutaneous Oxygen Pressure in Critical Limb Ischemia Before and After Treatment
This clinical trial update describes a completed study investigating near-infrared spectroscopy and transcutaneous oxygen pressure to assess…