Critical Illness
📧 Sign up to get email alerts when something new happens for Critical Illness.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS trial_result · 2021-03-16Clinical Trial Update: Trial of Supplemental Parenteral Nutrition in Under and Over Weight Critically Ill Patients (TOP-UP) [Phase 3]
A Phase 3 trial (TOP-UP) evaluating supplemental parenteral nutrition in underweight and overweight critically ill patients was terminated; …
-
CLINICAL_TRIALS trial_result · 2021-03-03Clinical Trial Update: Use of Nudges To Enhance Enrollment in Critical Care Research [NA]
Clinical trial update evaluating whether nudges can improve enrollment in critical care research; study completed with results posted.
-
CLINICAL_TRIALS trial_result · 2021-02-17Clinical Trial Update: Clonidine vs. Dexmedetomidine in Agitated Delirium in Intensive Care Patients [Phase 4]
A Phase 4 clinical trial comparing clonidine to dexmedetomidine for agitation in intensive care unit delirium.
-
CLINICAL_TRIALS trial_result · 2020-12-14Clinical Trial Update: REVERSE-AKI Randomized Controlled Pilot Trial [Phase 2]
A Phase 2 randomized pilot trial (REVERSE-AKI) focusing on acute kidney injury in critically ill patients has been completed.
-
CLINICAL_TRIALS trial_result · 2020-10-27Clinical Trial Update: PEP uP Protocol in Surgical Patients [Phase 4]
Phase 4 clinical trial update for the PEP uP protocol in surgical critically ill patients; study terminated with results posted.
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS trial_result · 2020-10-14Clinical Trial Update: Reaching Protein Target With SmofKabiven® Extra Nitrogen vs Olimel N9E During the Early Phase of Acute Critical Illness [Phase 4]
A Phase 4 clinical trial comparing SmofKabiven Extra nitrogen versus Olimel N9E in the early phase of acute critical illness was terminated.
-
CLINICAL_TRIALS trial_result · 2020-08-31Clinical Trial Update: Is There Any Correlation Between Respiratory Variation Ratios of Internal Jugular Vein and Inferior Vena Cava?
Clinical trial update investigating correlation between respiratory variation ratios of the internal jugular vein and inferior vena cava in …
-
CLINICAL_TRIALS trial_result · 2020-08-17Clinical Trial Update: Hypovitaminosis D in Neurocritical Patients [Phase 2, Phase 3]
Phase 2/3 trial on vitamin D supplementation for neurocritical patients has completed with results posted.
-
CLINICAL_TRIALS trial_result · 2020-07-13Clinical Trial Update: Pain, Agitation and Delirium (PAD) Protocol in the Duke CICU [Phase 4]
Phase 4 clinical trial update on the Pain, Agitation and Delirium (PAD) protocol in the Duke CICU; study terminated with results posted in 2…
-
CLINICAL_TRIALS trial_result · 2020-06-18Clinical Trial Update: Cholecalciferol Supplementation in Critically Ill Patients With Severe Vitamin D Deficiency. [Phase 2, Phase 3]
Clinical trial update on cholecalciferol (vitamin D3) supplementation in critically ill patients with severe vitamin D deficiency; study ter…
-
CLINICAL_TRIALS trial_result · 2020-06-18Clinical Trial Update: The Effect of Higher Protein Dosing in Critically Ill Patients Ultrasound a Sub-study [Phase 3]
Phase 3 trial evaluating higher protein dosing in critically ill patients; study withdrawn.
-
CLINICAL_TRIALS trial_result · 2020-06-16Clinical Trial Update: Compare Efficacy and Simplicity of Regional Citrate Anticoagulation With Fixed Dose Versus Adjusted Citrate Program [Phase 4]
Phase 4 trial comparing regional citrate anticoagulation with fixed-dose versus adjusted citrate program in critical illness and kidney repl…
-
CLINICAL_TRIALS trial_result · 2020-03-30Clinical Trial Update: Glycocalyx Damage in Critically Ill Patients
Clinical trial on glycocalyx damage in critically ill patients has completed with results posted.
-
CLINICAL_TRIALS trial_result · 2020-03-09Clinical Trial Update: Coated Devices to Decrease Infection in the Intensive Care Unit [Phase 1, Phase 2]
Phase 1/2 trial evaluating coated devices to reduce infection in critically ill patients; study completed.
-
CLINICAL_TRIALS trial_result · 2020-02-06Clinical Trial Update: Efficacy of PRUcalopride in Critically Ill Patients With Paralytic ILeus [Phase 3]
Phase 3 trial update evaluating the efficacy of PRUcalopride in critically ill patients with paralytic ileus.
-
CLINICAL_TRIALS trial_result · 2020-01-27Clinical Trial Update: Vitamin D to Improve Outcomes by Leveraging Early Treatment [Phase 3]
Phase 3 trial assessing vitamin D to improve outcomes in acute respiratory distress syndrome and vitamin D deficiency; study completed with …
-
CLINICAL_TRIALS trial_result · 2019-12-18Clinical Trial Update: Does Acetylsalicylic Acid Reduce the Mortality of Patients Admitted to an Intensive Care Unit [Phase 3]
Phase 3 trial investigating whether acetylsalicylic acid (aspirin) reduces mortality in ICU-admitted patients with critical illness; study T…
-
CLINICAL_TRIALS trial_result · 2019-11-25Clinical Trial Update: Isotonic Solutions and Major Adverse Renal Events Trial in the Non-Medical Intensive Care Unit (SMART-SURG) [NA]
A completed clinical trial comparing isotonic solutions in critically ill patients assessing risk of major adverse renal events; results pos…
-
CLINICAL_TRIALS trial_result · 2019-11-25Clinical Trial Update: Isotonic Solutions and Major Adverse Renal Events Trial in the Medical Intensive Care Unit [NA]
Clinical trial update on isotonic solutions and major adverse renal events in the ICU has been completed with results posted.
-
CLINICAL_TRIALS trial_result · 2019-10-10Clinical Trial Update: The Vitamin C, Hydrocortisone and Thiamine in Patients With Septic Shock Trial [Phase 2]
Phase 2 trial update for a vitamin C, hydrocortisone, and thiamine regimen in septic shock patients; study completed.
-
CLINICAL_TRIALS trial_result · 2019-09-24Clinical Trial Update: TAK-954 in Critically Ill Participants With Enteral Feeding Intolerance (EFI) [Phase 2]
Phase 2 trial of TAK-954 in critically ill patients with enteral feeding intolerance was terminated; results posted in 2019.
-
CLINICAL_TRIALS trial_result · 2019-09-06Clinical Trial Update: Midodrine for the Treatment of Refractory Hypotension [Phase 3]
A Phase 3 trial assessing midodrine for refractory hypotension in critically ill patients has completed with results posted in 2019.
-
CLINICAL_TRIALS trial_result · 2019-08-28Clinical Trial Update: Comparing Clinical Outcomes Between Ketamine-midazolam and Morphine-midazolam for Continous Sedation in ICU Patients. [Phase 2, Phase 3]
A terminated Phase 2/3 clinical trial comparing ketamine-midazolam versus morphine-midazolam for continuous sedation in critically ill ICU p…
-
CLINICAL_TRIALS trial_result · 2019-08-20Clinical Trial Update: Early Goal-Directed Sedation Compared With Standard Care in Mechanically Ventilated Critically Ill Patients [Phase 3]
Phase 3 trial comparing early goal-directed sedation to standard care in mechanically ventilated critically ill patients.
-
CLINICAL_TRIALS trial_result · 2019-08-20Clinical Trial Update: High "on Treatment" Platelet Reactivity in the Intensive Care Unit [Phase 2]
Phase 2 trial update focusing on high on-treatment platelet reactivity in ICU patients with critical illness.