Coronary Artery Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-07-03Clinical Trial Update: PRV-based Detection of CAD in Comparison to Standard Methods
This clinical trial update confirms the completion of a study evaluating PRV-based detection of coronary artery disease compared with standa…
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CLINICAL_TRIALS trial_result · 2018-06-29Clinical Trial Update: OCT Measures Predicting FFR
A completed clinical trial suggests that optical coherence tomography (OCT) measures may help predict fractional flow reserve (FFR) in patie…
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CLINICAL_TRIALS research · 2018-06-29Clinical Trial Update: Assessment of Change in Atherosclerotic Plaque by Serial CCTA
A clinical trial update evaluating changes in atherosclerotic plaque over time using serial coronary CT angiography in coronary artery disea…
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CLINICAL_TRIALS trial_result · 2018-06-28Clinical Trial Update: Long Term Outcomes Of Hybrid Percutaneous Approach
This document reports long-term outcomes from a hybrid percutaneous approach for treating coronary artery disease, based on a completed stud…
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CLINICAL_TRIALS trial_result · 2018-06-27Clinical Trial Update: Treatment Decisions for Multi-vessel CAD [NA]
A clinical trial (NCT02611050) evaluating treatment decisions for multi-vessel coronary artery disease was terminated. Sponsor Dartmouth-Hit…
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CLINICAL_TRIALS trial_result · 2018-06-26Clinical Trial Update: Ten-Year Outcomes of Stents Versus Coronary-Artery Bypass Grafting for Left Main Coronary Artery Disease
Ten-year results from a randomized comparison of coronary artery stenting (PCI) versus coronary artery bypass grafting for left main coronar…
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CLINICAL_TRIALS trial_result · 2018-06-26Clinical Trial Update: MIDCAB Versus DES in Proximal LAD Lesions [NA]
A completed clinical trial from the University of Leipzig compared minimally invasive direct coronary artery bypass (MIDCAB) with drug-eluti…
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CLINICAL_TRIALS research · 2018-06-26Clinical Trial Update: Tele - Cardiac Rehabilitation - Providing Secondary Prevention and Supervised Exercise Without Boundaries of Time and Space - PILOT 1 [NA]
Clinical trial update describing a pilot tele-cardiac rehabilitation program for secondary prevention and supervised exercise in coronary ar…
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CLINICAL_TRIALS trial_result · 2018-06-25Clinical Trial Update: FFRangio Accuracy vs. Standard FFR
A completed clinical trial comparing FFRangio accuracy to standard fractional flow reserve in patients with coronary artery disease, sponsor…
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CLINICAL_TRIALS research · 2018-06-25Clinical Trial Update: Artifact-Free High-Resolution Myocardial Perfusion MRI in Subjects With Abnormal Nuclear Myocardial Perfusion Studies [NA]
A completed clinical trial evaluating artifact-free high-resolution myocardial perfusion MRI in subjects with abnormal nuclear perfusion stu…
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CLINICAL_TRIALS research · 2018-06-21Clinical Trial Update: Predictability of Preoperative Hemoglobin A1c in Diabetic Patients Underwent Off-Pump Coronary Artery Bypass Surgery: A Retrospective Study.
This retrospective study assesses how well preoperative hemoglobin A1c predicts perioperative outcomes in diabetic patients undergoing off-p…
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CLINICAL_TRIALS trial_result · 2018-06-21Clinical Trial Update: Role of High Mobility Group Box 1 as a Prognostic Biomarker in Patients Undergoing Off-pump Coronary Artery Bypass Graft
This clinical trial assessed whether High Mobility Group Box 1 (HMGB1) can serve as a prognostic biomarker in patients undergoing off-pump c…
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CLINICAL_TRIALS trial_result · 2018-06-20Clinical Trial Update: Effect of Fimasartan for Modification of Atheroma Vulnerability in DEFERred Coronary Disease (FIMA-DEFER) [Phase 4]
Phase 4 trial evaluating fimasartan for modification of atheroma vulnerability in patients with deferred coronary disease has been terminate…
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CLINICAL_TRIALS trial_result · 2018-06-20Clinical Trial Update: Evaluation of the Strategy of "One-stop" Endovascular Treatment for Concomitant Coronary Artery Disease and Aortic Atherosclerotic Disease [Phase 4]
A Phase 4 clinical trial evaluating a one-stop endovascular strategy for patients with concurrent coronary artery disease and aortic atheros…
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CLINICAL_TRIALS trial_result · 2018-06-20Clinical Trial Update: Evaluation of Effectiveness and Safety of XIENCE PRIME Stent (IRIS-PRIME)
A completed clinical trial (IRIS-PRIME) evaluating the effectiveness and safety of the XIENCE PRIME drug-eluting stent for coronary artery d…
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CLINICAL_TRIALS trial_result · 2018-06-15Clinical Trial Update: A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD5718 After Single and Multiple Ascending Dose Administration to Healthy Japanese Men [Phase 1]
A Phase 1 study evaluating safety, tolerability, pharmacokinetics and pharmacodynamics of AZD5718 after single and multiple ascending doses …
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CLINICAL_TRIALS trial_result · 2018-06-15Clinical Trial Update: Use of FFR-CT in Stable Intermediate Chest Pain Patients With Severe Coronary Calcium Score
An observational trial evaluating fractional flow reserve by CT (FFR-CT) in stable intermediate chest pain patients with a severe coronary c…
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CLINICAL_TRIALS research · 2018-06-14Clinical Trial Update: Epidemiology of Insulin Growth Factor (IGF) and Cardiovascular Events
This completed clinical trial from Albert Einstein College of Medicine examined the epidemiology of insulin-like growth factor (IGF) and its…
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CLINICAL_TRIALS research · 2018-06-13Clinical Trial Update: Umbrella Review and Updated Systematic Review and Meta-analysis of Pulses/Legumes and Incident Cardiometabolic Diseases
This umbrella review and updated systematic review and meta-analysis evaluates the relationship between pulses/legumes intake and incident c…
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CLINICAL_TRIALS trial_result · 2018-06-11Clinical Trial Update: Optimizing Antithrombotic Care in Patients With AtriaL fibrillatiON and Coronary stEnt (OAC-ALONE) Study [Phase 4]
This Phase 4 clinical trial update reports the completion of the OAC-ALONE study evaluating antithrombotic strategies in patients with atria…
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CLINICAL_TRIALS trial_result · 2018-06-06Clinical Trial Update: Left Radial comparEd to Femoral Approach for CORonary Angiography in Patients With Previous CABG StuDy [NA]
The completed trial compared left radial versus femoral arterial access for coronary angiography in patients with prior CABG.
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CLINICAL_TRIALS trial_result · 2018-06-06Clinical Trial Update: Effects of Eicosapentaenoic Acid on Endothelial Function in Diabetic Subjects [Phase 3]
A Phase 3 trial evaluating the effects of eicosapentaenoic acid on endothelial function in adults with type 2 diabetes and coronary artery d…
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FDA label_change · 2018-05-31FDA Approved: LEXISCAN — Supplemental Application (Astellas Pharma US, Inc.)
FDA approved a supplemental application for LEXISCAN (regadenoson), resulting in changes to the drug's labeling.
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CLINICAL_TRIALS research · 2018-05-31Clinical Trial Update: Study of the Orsiro Drug Eluting Stent System [NA]
Clinical trial update for the Orsiro Drug Eluting Stent System in coronary artery disease, sponsored by Biotronik AG, with the trial status …
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CLINICAL_TRIALS trial_result · 2018-05-30Clinical Trial Update: Myocardial Injury After Elective Coronary Stenting
This clinical trial update reports results from a completed study examining myocardial injury after elective coronary stenting in patients w…