Coronary Artery Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2022-09-09Clinical Trial Update: Wall Shear Stress and Neointimal Healing Following PCI in Angulated Coronary Vessels [NA]
A completed clinical trial investigating wall shear stress and neointimal healing after PCI in angulated coronary vessels; results posted in…
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CLINICAL_TRIALS research · 2022-09-01Clinical Trial Update: Impact of CYP2C19 Genotype-guided Clopidogrel and Ticagrelor Treatment on Platelet Function Test and Metabolomics Profile [Phase 4]
Phase 4 clinical trial evaluating how CYP2C19 genotype-guided clopidogrel and ticagrelor treatment affects platelet function and metabolomic…
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FDA approval · 2022-08-31FDA Approved: REGADENOSON — Original Application (Hospira, Inc.)
FDA approved Hospira's Regadenoson as a generic (ANDA 214349) for use as a pharmacologic stress agent to detect myocardial ischemia in patie…
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CLINICAL_TRIALS trial_result · 2022-08-18Clinical Trial Update: Vorapaxar on Thrombin Generation and Coagulability [Phase 4]
Phase 4 trial update evaluating vorapaxar's impact on thrombin generation and coagulability in patients with coronary artery disease and per…
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CLINICAL_TRIALS trial_result · 2022-08-12Clinical Trial Update: Nociception-directed Erector Muscle Spinae Plane Block in Open Heart Surgery [Phase 4]
Phase 4 trial update on nociception-directed erector muscle plane block for open heart surgery, completed.
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CLINICAL_TRIALS trial_result · 2022-08-04Clinical Trial Update: Efficacy of Dexamethasone to Improve Clinical Outcomes in Coronary Artery Bypass Patients [Phase 4]
Phase 4 trial update evaluating dexamethasone for improving clinical outcomes in patients undergoing coronary artery bypass.
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CLINICAL_TRIALS trial_result · 2022-07-22Clinical Trial Update: 18F-fluoride (18F-NaF) PET for Identifying Coronary Atherosclerotic Plaques [Phase 4]
Phase 4 trial update on using 18F-fluoride PET to identify coronary atherosclerotic plaques.
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CLINICAL_TRIALS trial_result · 2022-07-22Clinical Trial Update: Statin Recapture Therapy Before Coronary Artery Bypass Grafting [Phase 4]
Phase 4 trial investigating statin recapture therapy prior to coronary artery bypass grafting completed.
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CLINICAL_TRIALS trial_result · 2022-07-21Clinical Trial Update: SAPT Versus DAPT in Incomplete Revascularization After CABG [Phase 3]
Phase 3 clinical trial comparing SAPT versus DAPT in incomplete revascularization after CABG is currently recruiting for coronary artery dis…
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FDA approval · 2022-07-12FDA Approved: REGADENOSON — Original Application (Almaject, Inc.)
The FDA approved Almaject, Inc.'s original Abbreviated New Drug Application for regadenoson, a pharmacologic stress agent used in myocardial…
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FDA approval · 2022-07-08FDA Approved: ATORVASTATIN CALCIUM — Supplemental Application (NIVAGEN PHARMACEUTICALS, INC.)
FDA approved the supplemental application for atorvastatin calcium from NIVAGEN Pharmaceuticals, Inc., authorizing the generic product.
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FDA approval · 2022-07-08FDA Approved: ISOSORBIDE DINITRATE — Original Application (Advagen Pharma Ltd)
FDA approved the original application for isosorbide dinitrate, a generic anti-anginal medication, from Advagen Pharma Ltd.
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CLINICAL_TRIALS trial_result · 2022-07-07Clinical Trial Update: Platelet Inhibition With Ticagrelor 60 mg Versus Ticagrelor 90 mg in Elderly Patients With ACS [Phase 3]
A Phase 3 trial comparing ticagrelor 60 mg versus ticagrelor 90 mg in elderly patients with acute coronary syndrome has completed recruitmen…
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CLINICAL_TRIALS trial_result · 2022-06-28Clinical Trial Update: SHIELD II Clinical Investigation [NA]
Clinical trial SHIELD II has been terminated; results posted in 2022. No specific safety or efficacy conclusions are provided in the summary…
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CLINICAL_TRIALS trial_result · 2022-06-27Clinical Trial Update: Pharmacodynamic Effects of Low-dose Rivaroxaban With Antiplatelet Therapies [Phase 4]
Phase 4 trial examining the pharmacodynamic effects of low-dose rivaroxaban in combination with antiplatelet therapies; results completed wi…
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CLINICAL_TRIALS trial_result · 2022-06-23Clinical Trial Update: Exploring the Efficacy and Safety of Rivaroxaban to Support Elective Percutaneous Coronary Intervention [Phase 2]
Phase 2 clinical trial update evaluating rivaroxaban for efficacy and safety in supporting elective percutaneous coronary intervention.
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CLINICAL_TRIALS trial_result · 2022-06-07Clinical Trial Update: Evaluate Carotid Artery Plaque Composition by Magnetic Resonance Imaging in People Receiving Cholesterol Medication [Phase 4]
Phase 4 trial updating on carotid plaque composition assessment by MRI in people on cholesterol medication; study completed with results pos…
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CLINICAL_TRIALS trial_result · 2022-06-01Clinical Trial Update: Intracoronary of Nicorandil and Verapamil to Reduce the Occurrence of Periprocedural Myocardial Injury [Phase 2]
Phase 2 clinical trial evaluating intracoronary nicorandil and verapamil to reduce periprocedural myocardial injury in coronary artery disea…
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FDA approval · 2022-05-23FDA Approved: REGADENOSON — Original Application (International Medication Systems, Limited)
FDA approved an original ANDA for Regadenoson by International Medication Systems, Limited, authorizing a generic regadenoson product for us…
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CLINICAL_TRIALS research · 2022-05-18Clinical Trial Update: Retrospective Experience Of CIED Implantation
A retrospective clinical trial update reviewing outcomes of cardiac implantable electronic device implantation.
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FDA approval · 2022-05-17FDA Approved: TECHNETIUM TC 99M SESTAMIBI — Supplemental Application (Curium US LLC)
FDA approved a supplemental application for Technetium Tc-99m Sestamibi, updating its labeling and approved use in diagnostic myocardial per…
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CLINICAL_TRIALS trial_result · 2022-05-12Clinical Trial Update: Dose-finding Study of Colchicine in Type 2 Diabetic Patients With Coronary Artery Disease [Phase 2]
Phase 2 dose-finding study of colchicine in Type 2 diabetes patients with coronary artery disease completed.
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CLINICAL_TRIALS trial_result · 2022-05-10Clinical Trial Update: Physiologic Assessment of Coronary Stenosis Following PCI
A completed clinical trial studying physiologic assessment of coronary stenosis after PCI, with results posted in 2022.
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CLINICAL_TRIALS trial_result · 2022-04-25Clinical Trial Update: An Open-label, Non-comparative Study to Document the Tolerability to Ramipril in Patients With at Least One High Risk for Developing a Major Cardiovascular Event [Phase 4]
Open-label Phase 4 study assessing tolerability of ramipril in patients at high risk for major cardiovascular events; completed.
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CLINICAL_TRIALS trial_result · 2022-04-22Clinical Trial Update: Coronary Artery Disease Progression in Patients With Prediabetes [Phase 4]
Phase 4 trial update evaluating progression of coronary artery disease in patients with prediabetes, completed.