Coronary Artery Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: Atherosclerosis in the Coronary and Carotid Arteries
This document notes that a National Heart, Lung, and Blood Institute clinical trial investigating atherosclerosis in the coronary and caroti…
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CLINICAL_TRIALS trial_result · 2008-02-25Clinical Trial Update: Propofol Pharmacokinetics and Pharmacodynamics During Cardiopulmonary Bypass
This clinical trial update reports on the pharmacokinetics and pharmacodynamics of propofol during cardiopulmonary bypass in patients underg…
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FDA approval · 2008-02-21FDA Approved: ISOSORBIDE DINITRATE — Supplemental Application (Sandoz Inc.)
The FDA approved a supplemental application for Sandoz Inc.'s isosorbide dinitrate product.
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CLINICAL_TRIALS trial_result · 2008-01-29Clinical Trial Update: Stem Cell Study for Patients With Heart Disease [Phase 1]
Phase 1 stem cell study in patients with ischemic heart disease has completed its Phase 1 status, with endpoints related to myocardial ische…
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CLINICAL_TRIALS trial_result · 2008-01-29Clinical Trial Update: Slow Coronary Artery Flow: Influence on Morbidity and Mortality
A clinical trial update investigating whether slow coronary artery flow influences morbidity and mortality in patients with coronary artery …
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CLINICAL_TRIALS trial_result · 2008-01-25Clinical Trial Update: Evaluating a Low-Literacy Discharge Medication Education Tool [NA]
This is a completed clinical trial evaluating a discharge medication education tool designed for low-literacy patients. The study targeted c…
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FDA approval · 2008-01-15FDA Approved: PRAVASTATIN SODIUM — Original Application (Aurobindo Pharma Limited)
FDA approved the original application for pravastatin sodium by Aurobindo Pharma Limited, confirming a generic pravastatin product. The drug…
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CLINICAL_TRIALS trial_result · 2008-01-11Clinical Trial Update: Sirolimus- and Paclitaxel-Eluting Stents for Small Vessels (ISAR-SMART-3) [Phase 4]
A Phase 4 clinical trial update reports completion of ISAR-SMART-3 evaluating sirolimus- and paclitaxel-eluting stents for small coronary ve…
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CLINICAL_TRIALS trial_result · 2008-01-11Clinical Trial Update: Nonpolymer- and Polymer-Based Drug-Eluting Stents for Restenosis (ISAR-TEST-1) [Phase 4]
Phase 4 trial ISAR-TEST-1 evaluated nonpolymer- and polymer-based drug-eluting stents for restenosis in coronary artery disease. The study s…
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CLINICAL_TRIALS trial_result · 2008-01-07Clinical Trial Update: PLASMA 2 Trial: Examination of Once Daily (QD) Dosing of A-002 In Subjects With Stable Coronary Artery Disease [Phase 2]
This document provides an update on the PLASMA 2 Phase 2 trial evaluating once-daily dosing of A-002 in subjects with stable coronary artery…
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CLINICAL_TRIALS trial_result · 2008-01-07Clinical Trial Update: Distal Protection Combined With PTCA in AMI Patients [Phase 2]
Phase 2 clinical trial evaluating distal protection devices combined with percutaneous transluminal coronary angioplasty (PTCA) in acute myo…
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CLINICAL_TRIALS trial_result · 2007-12-28Clinical Trial Update: Changes in Cerebrovascular Reactivity During Cognitive Activation After Cardiopulmonary Bypass: Relation With Intraoperative Embolic Load and Postoperative Neuropsychological Dysfunctions [NA]
This completed clinical trial update examines how cerebrovascular reactivity during cognitive tasks changes after cardiopulmonary bypass and…
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FDA approval · 2007-12-28FDA Approved: PRAVASTATIN SODIUM — Supplemental Application (CIPLA USA INC.)
FDA approved a supplemental application for pravastatin sodium submitted by Cipla USA Inc., signaling an additional regulatory approval for …
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CLINICAL_TRIALS trial_result · 2007-12-21Clinical Trial Update: Trial to Study the Effects of Supplementary Omega-3 on Serum C-Reactive Protein Levels [Phase 4]
A Phase 4 trial studying the effects of supplementary omega-3 on serum C-reactive protein levels in coronary artery disease and atherosclero…
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CLINICAL_TRIALS trial_result · 2007-12-11Clinical Trial Update: Capturing Outcomes of Clinical Activities Performed by a Rounding Pharmacist Practising in a Team Environment [Phase 4]
Phase 4 clinical trial update from the University of Alberta describes outcomes of clinical activities performed by a rounding pharmacist in…
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CLINICAL_TRIALS trial_result · 2007-12-10Clinical Trial Update: A Coronary IVUS Study to Compare Torcetrapib/Atorvastatin to Atorvastatin Alone in Subjects With Coronary Heart Disease [Phase 3]
A Phase 3 trial comparing torcetrapib/atorvastatin to atorvastatin alone in patients with coronary heart disease has completed.
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CLINICAL_TRIALS trial_result · 2007-12-10Clinical Trial Update: Study Evaluating GAP-486 on Heart Rhythm in Patients With Coronary Artery Disease [Phase 2]
Phase 2 study evaluating GAP-486 on heart rhythm in patients with coronary artery disease has been terminated.
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CLINICAL_TRIALS trial_result · 2007-12-05Clinical Trial Update: Comparison of Diagnostic Rest/Stress SPECT Results for Patients With Myocardial Ischemia and Infarction Using Myoview in Both Single and Dual Isotope Acquisition Approaches [Phase 4]
Phase 4 trial comparing rest/stress SPECT imaging results using Myoview with single versus dual isotope acquisition in patients with coronar…
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CLINICAL_TRIALS trial_result · 2007-12-04Clinical Trial Update: Long-Term Cognitive Decline After Coronary Artery Bypass Grafting: is Off-Pump Surgery Beneficial? [Phase 4]
A completed Phase 4 trial evaluated whether off-pump coronary artery bypass grafting affects long-term cognitive decline in patients with co…
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CLINICAL_TRIALS trial_result · 2007-12-04Clinical Trial Update: Efficacy of FX06 in the Prevention of Myocardial Reperfusion Injury [Phase 2]
Phase 2 trial evaluating FX06 for the prevention of myocardial reperfusion injury has completed.
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CLINICAL_TRIALS trial_result · 2007-12-03Clinical Trial Update: Computed Tomographic Angiography or Conventional Coronary Angiography in Clinical Decision Making
This completed trial compared computed tomographic angiography to conventional coronary angiography for guiding clinical decision making in …
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CLINICAL_TRIALS trial_result · 2007-11-20Clinical Trial Update: Coronary Computed Tomographic Angiography in Emergency Department Chest Pain Patients at Intermediate Risk of Acute Coronary Syndrome [Phase 3]
A Phase 3 clinical trial evaluating coronary computed tomographic angiography in emergency department chest pain patients at intermediate ri…
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CLINICAL_TRIALS trial_result · 2007-11-20Clinical Trial Update: Chlamydia and Mycoplasma in Coronary Artery Disease
This clinical trial update notes the completion of a study examining the role of Chlamydia and Mycoplasma infections in coronary artery dise…
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CLINICAL_TRIALS trial_result · 2007-11-16Clinical Trial Update: A Safety and Efficacy Study to Confirm the Cardioprotective Effects of MC-1 in Patients Undergoing High-Risk CABG [Phase 3]
Phase 3 study assessing safety and efficacy of MC-1 in high-risk coronary artery bypass graft patients has completed.
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CLINICAL_TRIALS research · 2007-11-15Clinical Trial Update: Prospective Data Collection of IVMRI Cases [NA]
Clinical trial update from TopSpin Medical describing prospective data collection of intravascular MRI (IVMRI) cases focused on coronary pla…