Congenital Heart Disease
📧 Sign up to get email alerts when something new happens for Congenital Heart Disease.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS trial_result · 2022-11-02Clinical Trial Update: " Evaluation of Safety and Efficacy of Empagliflozin and Sacubitril/Valsartan for CHF With Reduced Ejection Fraction in ACHD " [Phase 2, Phase 3]
Clinical trial evaluating safety and efficacy of empagliflozin and sacubitril/valsartan for heart failure with reduced ejection fraction in …
-
CLINICAL_TRIALS trial_result · 2022-09-21Clinical Trial Update: Stress Ulcer Prophylaxis Versus Placebo in Critically Ill Infants With Congenital Heart Disease [Phase 4]
Phase 4 clinical trial comparing stress ulcer prophylaxis versus placebo in critically ill infants with congenital heart disease has complet…
-
CLINICAL_TRIALS trial_result · 2022-09-13Clinical Trial Update: Clinical Study Assessing the Efficacy and Safety of Macitentan in Fontan-palliated Subjects [Phase 3]
Phase 3 trial evaluating macitentan in Fontan-palliated congenital heart disease completed with results posted.
-
CLINICAL_TRIALS trial_result · 2022-05-18Clinical Trial Update: A Study of the Safety and Pharmacokinetics of Apixaban Versus Vitamin K Antagonist (VKA) or Low Molecular Weight Heparin (LMWH) in Pediatric Subjects With Congenital or Acquired Heart Disease Requiring Anticoagulation [Phase 2]
Phase 2 study evaluating safety and pharmacokinetics of apixaban vs VKA/LMWH in pediatric patients with congenital or acquired heart disease…
-
CLINICAL_TRIALS trial_result · 2022-05-09Clinical Trial Update: The Effect of Anesthesia on Neurodevelopmental Outcome (NDO) [NA]
Clinical trial update on the effect of anesthesia on neurodevelopmental outcomes has completed recruitment with results posted.
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS trial_result · 2022-03-28Clinical Trial Update: Pharmacokinetic, Pharmacodynamic, Safety, and Efficacy Study of Rivaroxaban for Thromboprophylaxis in Pediatric Participants 2 to 8 Years of Age After the Fontan Procedure [Phase 3]
Phase 3 pediatric trial evaluating rivaroxaban for thromboprophylaxis after Fontan procedure in children ages 2 to 8, assessing PK/PD, safet…
-
CLINICAL_TRIALS trial_result · 2022-03-15Clinical Trial Update: Prevention of Post-Operative Cardiac Arrhythmias [Phase 4]
Phase 4 clinical trial update on prevention of post-operative cardiac arrhythmias.
-
CLINICAL_TRIALS trial_result · 2022-01-06Clinical Trial Update: Evaluating Precision of Therapy - Milrinone [Phase 2]
Phase 2 clinical trial update evaluating milrinone for congenital heart disease has completed.
-
CLINICAL_TRIALS trial_result · 2021-12-02Clinical Trial Update: The Medtronic Harmony™ Transcatheter Pulmonary Valve Clinical Study [NA]
This clinical trial update reports posted results for the Harmony transcatheter pulmonary valve in congenital heart disease and Tetralogy of…
-
CLINICAL_TRIALS trial_result · 2021-11-02Clinical Trial Update: High Dose Methylprednisolone Verses Low Dose in Correction of Congenital Acynotic Heart Disease [Phase 4]
Phase 4 clinical trial comparing high-dose vs low-dose methylprednisolone in correction of congenital acynotic heart disease; current status…
-
CLINICAL_TRIALS trial_result · 2021-07-28Clinical Trial Update: Role of Sildenafil for Fontan Associated Liver Disease (SiFALD) Study [Phase 3]
Phase 3 trial update evaluating sildenafil for Fontan-associated liver disease (SiFALD) completed with posted results in 2021.
-
CLINICAL_TRIALS trial_result · 2021-03-19Clinical Trial Update: Platelets or Fibrinogen as First-line Treatment for Bleeding During Pedatric Heart Surgery [Phase 2]
Phase 2 clinical trial investigating use of platelets or fibrinogen as first-line treatment for bleeding during pediatric heart surgery.
-
CLINICAL_TRIALS trial_result · 2021-01-20Clinical Trial Update: Autologous Umbilical Cord Blood Treatment of Neonate With CHD [Phase 1, Phase 2]
Phase 1/2 clinical trial update investigating autologous umbilical cord blood treatment for neonates with congenital heart disease and relat…
-
CLINICAL_TRIALS trial_result · 2021-01-19Clinical Trial Update: Training in Exercise Activities and Motion for Growth [NA]
Clinical trial evaluating exercise training and motion for growth in individuals with single-ventricle physiology has completed and results …
-
CLINICAL_TRIALS trial_result · 2020-12-28Clinical Trial Update: Sodium Bicarbonate to Prevent Acute Kidney Injury in Children Undergoing Cardiac Surgery [Phase 2]
Phase 2 trial investigating sodium bicarbonate to prevent acute kidney injury in children undergoing cardiac surgery; study status terminate…
-
CLINICAL_TRIALS trial_result · 2020-07-29Clinical Trial Update: Acute Effects of Inhaled Treprostinil in Fontan Patients [Phase 2]
Phase 2 trial update on the acute effects of inhaled treprostinil in Fontan patients with congenital heart disease; study terminated with re…
-
CLINICAL_TRIALS trial_result · 2020-07-07Clinical Trial Update: Early Use of Vasopressin in Post-Fontan Management [Phase 2, Phase 3]
Phase 2/3 trial assessing early use of vasopressin in post-Fontan management for single-ventricle circulation; results posted after completi…
-
CLINICAL_TRIALS trial_result · 2020-07-01Clinical Trial Update: Thiamine Influenced on Substrate Energy Effectiveness in Indonesian Children Undergoing Cardiopulmonary Bypass [Phase 4]
Phase 4 clinical trial investigating the effect of thiamine on substrate energy efficiency in Indonesian children undergoing cardiopulmonary…
-
CLINICAL_TRIALS trial_result · 2019-08-21Clinical Trial Update: Spironolactone in Adult Congenital Heart Disease [Phase 2]
Phase 2 trial update for spironolactone in adults with congenital heart disease and heart failure, with results posted.
-
CLINICAL_TRIALS trial_result · 2019-06-18Clinical Trial Update: Corticosteroid Therapy in Neonates Undergoing Cardiopulmonary Bypass [NA]
Clinical trial update on using corticosteroid therapy in neonates undergoing cardiopulmonary bypass; trial completed with results posted.
-
CLINICAL_TRIALS trial_result · 2019-05-07Clinical Trial Update: Fibrinogen Concentrate vs Cryoprecipitate [Phase 4]
Phase 4 trial comparing fibrinogen concentrate with cryoprecipitate in congenital heart disease completed with results posted.
-
CLINICAL_TRIALS trial_result · 2019-02-21Clinical Trial Update: Adult Congenital Heart Disease Surgery
The clinical trial NCT00446160 on adult congenital heart disease surgery sponsored by Emory University has completed.
-
CLINICAL_TRIALS trial_result · 2019-01-30Clinical Trial Update: Prophylactic Use of Milrinone After Congenital Heart Surgery in Infants [Phase 3]
This is a Phase 3 clinical trial update evaluating prophylactic milrinone to prevent low cardiac output syndrome after congenital heart surg…
-
CLINICAL_TRIALS trial_result · 2018-12-21Clinical Trial Update: Intraoperative Dexamethasone in Pediatric Cardiac Surgery [Phase 3]
Phase 3 trial evaluating intraoperative dexamethasone in pediatric cardiac surgery has completed.
-
CLINICAL_TRIALS trial_result · 2018-09-05Clinical Trial Update: Effect of Sevoflurane in Postoperative Troponin I Levels in Children Undergoing Congenital Heart Defects Surgery [Phase 4]
Phase 4 trial updating the effect of sevoflurane on postoperative troponin I levels in children undergoing surgery for congenital heart defe…