Congenital Heart Defect
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: Impact of Thymectomy on Immunity in Infants After Cardiac Surgery [NA]
A Nantes University Hospital trial is evaluating how thymectomy during infancy after cardiac surgery affects immune function; the study is c…
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: Auto-immunity and Pulmonary Arterial Hypertension [NA]
Status update indicating a trial on auto-immunity and pulmonary arterial hypertension sponsored by Assistance Publique - Hôpitaux de Paris i…
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CLINICAL_TRIALS trial_result · 2026-03-17Clinical Trial Update: A Feasibility Study of Physical Activity After Surgical or Catheterization Intervention [NA]
A completed feasibility clinical trial evaluating physical activity after surgical or catheter-based intervention for congenital heart defec…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: The Association Between Tau & GFAP and Postoperative Neurological Impairment in Patients Undergoing Cardiac Surgery
This clinical trial update describes a study investigating the association between Tau and GFAP biomarkers and postoperative neurological im…
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: COMPASSION S3 - Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients With Pulmonary Valve Dysfunction [NA]
This clinical trial update reports that the COMPASSION S3 study evaluating the SAPIEN 3 transcatheter heart valve for pulmonary valve dysfun…
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CLINICAL_TRIALS trial_result · 2025-12-23Clinical Trial Update: Study on the Safety and Effectiveness of a Biodegradable Patent Foramen Ovale Occluder System [NA]
Clinical trial update on a biodegradable patent foramen ovale occluder system intended to treat PFO-related conditions. The study status is …
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CLINICAL_TRIALS research · 2025-12-11Clinical Trial Update: Genetics of Ventriculo-arterial Discordance [NA]
Clinical trial entry for a genetics study on ventriculo-arterial discordance in congenital heart defects; currently active but not recruitin…
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CLINICAL_TRIALS trial_result · 2025-09-04Clinical Trial Update: Pulsta® Transcatheter Pulmonary Valve Korean Multicenter Study [NA]
The Pulsta Transcatheter Pulmonary Valve Korean Multicenter Study has completed (status: COMPLETED) according to the ClinicalTrials.gov entr…
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CLINICAL_TRIALS research · 2025-07-22Clinical Trial Update: Xeltis Bioabsorbable Pulmonary Valved Conduit Pivotal Study [NA]
Xeltis reports that its pivotal study of a bioabsorbable pulmonary valved conduit for congenital heart defects is currently active but not r…
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CLINICAL_TRIALS trial_result · 2025-07-14Clinical Trial Update: Effectiveness of CRD-4730 in Participants With Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT) [Phase 2]
A Phase 2 study evaluating CRD-4730 in people with catecholaminergic polymorphic ventricular tachycardia was terminated.
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CLINICAL_TRIALS research · 2025-06-25Clinical Trial Update: Clinical Readiness Skin Punch Biopsy Sample Collections
HeartWorks, Inc. is recruiting for a study involving skin punch biopsy sample collection to support research readiness in congenital heart d…
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CLINICAL_TRIALS research · 2025-06-17Clinical Trial Update: NIRS in Congenital Heart Defects - Correlation With Echocardiography
Clinical trial update on a McGill-led study assessing near-infrared spectroscopy (NIRS) in congenital heart defects and its correlation with…
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CLINICAL_TRIALS research · 2025-05-07Clinical Trial Update: Safety and Efficacy Study of reSept ASD Occluder for Treating Secundum ASD [NA]
Clinical trial update on the safety and efficacy study of the reSept ASD Occluder for treating secundum atrial septal defects. The study sta…
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CLINICAL_TRIALS research · 2025-04-10Clinical Trial Update: Swiss National Registry of Grown up Congenital Heart Disease Patients
ClinicalTrials.gov entry NCT02258724 reports a recruiting study in Switzerland focused on adult congenital heart disease; the project appear…
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CLINICAL_TRIALS trial_result · 2025-03-21Clinical Trial Update: Investigation of the Relationship Between Blood Transfusion Volume and Development of Renal Failure in Pediatric Patients Undergoing Cardiovascular Surgery
The trial assessed whether the amount of blood transfused during pediatric cardiovascular surgery influences the risk of acute kidney injury…
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CLINICAL_TRIALS research · 2025-03-14Clinical Trial Update: Role of Cardiac AngioMR in Diagnosis of Cardiac and Vascular Anomalies in Adult Patients with Turner Syndrome
This clinical trial is evaluating the use of Cardiac AngioMRI to diagnose cardiac and vascular abnormalities in adult patients with Turner s…
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CLINICAL_TRIALS research · 2024-08-21Clinical Trial Update: Electro-acupuncture (EA) in Children Undergoing Procedures for Congenital Heart Defects. [NA]
The ClinicalTrials.gov entry indicates the electro-acupuncture study in children undergoing procedures for congenital heart defects has comp…
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CLINICAL_TRIALS trial_result · 2023-06-23Clinical Trial Update: Effect of Phosphodiesterase-5 Inhibition With Tadalafil on SystEmic Right VEntricular Size and Function [Phase 3]
Phase 3 trial update evaluating whether tadalafil, a phosphodiesterase-5 inhibitor, affects systemic right ventricular size and function in …
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CLINICAL_TRIALS trial_result · 2023-05-19Clinical Trial Update: The Effects of Inhaled Nitric Oxide After Fontan Operation [Phase 2, Phase 3]
Phase 2/3 trial investigating inhaled nitric oxide after Fontan operation has completed with results posted.
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CLINICAL_TRIALS research · 2021-09-13Clinical Trial Update: A Pilot Study of Optic Nerve Ultrasound Following Cardiopulmonary Bypass [NA]
A pilot study evaluating optic nerve ultrasound after cardiopulmonary bypass in congenital heart disease patients; status completed with res…
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CLINICAL_TRIALS trial_result · 2018-03-30Clinical Trial Update: Post-market Clinical Follow-up Study With Magnetic Resonance Imaging Conditional Guide Wire [NA]
A post-market clinical follow-up study of an MRI-conditional guide wire for congenital heart defects has been completed.
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CLINICAL_TRIALS trial_result · 2017-11-20Clinical Trial Update: Contegra Versus Pulmonary Homograft for Right Ventricular Outflow Tract Reconstruction in Newborns
A completed clinical trial comparing Contegra bovine jugular vein conduit to pulmonary homograft for right ventricular outflow tract reconst…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Melody Transcatheter Pulmonary Valve Study: Post Approval Study of the Investigational Device Exemption Cohort [NA]
Clinical trial update for Melody transcatheter pulmonary valve post-approval study; study completed with results posted in 2017.
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CLINICAL_TRIALS withdrawal · 2016-11-25Clinical Trial Update: Tranexamic Acid Effect on Platelet Aggregation Following Infant Cardiopulmonary Bypass [Phase 4]
The Phase 4 trial evaluating tranexamic acid's effect on platelet aggregation in infants undergoing cardiopulmonary bypass has been withdraw…
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CLINICAL_TRIALS research · 2016-08-31Clinical Trial Update: Prospective Evaluation of Changes in Tissue Oxygen Saturation in Brain and Kidney in Children Admitted to Intensive Care in the Postoperative Period of Cardiac Surgery
A prospective study evaluating changes in tissue oxygen saturation in the brain and kidney of children in the ICU during the postoperative p…