Common Variable Immunodeficiency
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Pilot Trial of Allogeneic Blood or Marrow Transplantation for Primary Immunodeficiencies [Phase 2]
This update describes a Phase 2 pilot trial evaluating allogeneic blood or marrow transplantation for primary immunodeficiency disorders, wi…
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CLINICAL_TRIALS trial_result · 2026-04-20Clinical Trial Update: Improving the Diagnosis of Common Variable Immune Deficiency
A UCLA-led clinical trial aimed at improving the diagnosis of Common Variable Immunodeficiency has completed.
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Immune Regulation in Patients With Common Variable Immunodeficiency and Related Inborn Errors of Immunity (IEI)
The update describes an ongoing NIAID-sponsored study on immune regulation in patients with common variable immunodeficiency and related inb…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Natural History of Bronchiectasis
NHLBI-funded clinical trial update studying the natural history of bronchiectasis; the study is currently recruiting and includes bronchiect…
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CLINICAL_TRIALS trial_result · 2026-03-17Clinical Trial Update: Allogeneic Hematopoietic Cell Transplantation for Disorders of T-cell Proliferation and/or Dysregulation [Phase 2]
A Phase 2 study evaluating allogeneic hematopoietic cell transplantation for disorders of T-cell proliferation and/or dysregulation, sponsor…
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: Respiratory Microbiota and Immune Response in CVID
The clinical trial NCT06173128 in common variable immunodeficiency has completed. It studied respiratory microbiota and immune responses in …
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: Hematopoietic Stem Cell Transplantation (HSCT) for Common Variable Immunodeficiency (CVID) and Other Autoimmune Manifestations of Primary Immune Regulatory Disorders (PIRD) [Phase 2]
A Phase 2 clinical trial update indicates ongoing recruitment for an allogeneic hematopoietic stem cell transplantation approach addressing …
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Immune Disorder HSCT Protocol [Phase 2]
Phase 2 clinical trial update on a hematopoietic stem cell transplant protocol for several inherited immune deficiency disorders; the study …
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CLINICAL_TRIALS trial_result · 2026-02-12Clinical Trial Update: Leniolisib for Immune Dysregulation in CVID [Phase 2]
Phase 2 clinical trial evaluating leniolisib for immune dysregulation in Common Variable Immunodeficiency (CVID) is currently active but not…
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CLINICAL_TRIALS trial_result · 2026-01-15Clinical Trial Update: Allogeneic Hematopoietic Stem Cell Transplant for Patients With Primary Immune Deficiencies [NA]
This clinical trial investigates allogeneic hematopoietic stem cell transplantation as a treatment for primary immune deficiencies, includin…
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: Severe PID With Lymphoproliferation and Neutropenia [NA]
The clinical trial investigating severe primary immunodeficiency with lymphoproliferation and neutropenia in common variable immunodeficienc…
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: Senolytics Treatment of Interstitial Lung Disease in Common Variable Immunodeficiency [Phase 2]
Phase 2 clinical trial investigating senolytic therapy for interstitial lung disease in people with common variable immunodeficiency; the st…
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CLINICAL_TRIALS trial_result · 2025-12-18Clinical Trial Update: Bronchiectasis Prevalence in Patients With Primary Humoral Immunodefiency in Champagne-Ardenne Region, France [NA]
A completed clinical trial update assessing the prevalence of bronchiectasis in patients with primary humoral immunodeficiency, including CV…
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CLINICAL_TRIALS trial_result · 2025-12-15Clinical Trial Update: Sequential Cadaveric Lung and Bone Marrow Transplant for Immune Deficiency Diseases [Phase 1, Phase 2]
This clinical trial update describes an early-phase study evaluating sequential cadaveric lung transplantation followed by bone marrow trans…
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CLINICAL_TRIALS research · 2025-12-10Clinical Trial Update: Peripheral Helper T-cells in Common Variable ImmunoDeficiency [NA]
Clinical trial update about peripheral helper T-cells in Common Variable Immunodeficiency, currently not recruiting.
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CLINICAL_TRIALS research · 2025-11-06Clinical Trial Update: Abatacept for the Treatment of Common Variable Immunodeficiency With Interstitial Lung Disease [Phase 2]
A Phase 2 clinical trial evaluating abatacept for common variable immunodeficiency with interstitial lung disease is currently recruiting.
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CLINICAL_TRIALS research · 2025-09-16Clinical Trial Update: Allogeneic Hematopoietic Stem Cell Transplant for Patients With Inborn Errors of Immunity [Phase 2]
A Phase 2 clinical trial exploring allogeneic hematopoietic stem cell transplantation for patients with inborn errors of immunity is current…
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CLINICAL_TRIALS research · 2025-06-03Clinical Trial Update: COVID-19 Vaccine Responses in PIDD Subjects
This clinical trial update describes COVID-19 vaccine responses in patients with primary immunodeficiency diseases (PIDD), including X-linke…
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CLINICAL_TRIALS research · 2025-03-11Clinical Trial Update: Usage of Spirometry in Managing IgG Therapy in CVID with Airway Disease [Phase 4]
A Phase 4 clinical trial investigates using spirometry to guide intravenous immunoglobulin (IgG) therapy in Common Variable Immunodeficiency…
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CLINICAL_TRIALS research · 2024-12-09Clinical Trial Update: Prediction of Portal Hypertension in Patients With CVID (CVID-pHT)
A clinical trial is evaluating methods to predict portal hypertension in patients with Common Variable Immunodeficiency (CVID); the study is…
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CLINICAL_TRIALS trial_result · 2023-09-15Clinical Trial Update: Conditioning Regimen for Allogeneic Hematopoietic Stem-Cell Transplantation [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating conditioning regimens for allogeneic hematopoietic stem-cell transplantation has completed recruitment…
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CLINICAL_TRIALS trial_result · 2022-03-11Clinical Trial Update: Study of Efficacy of CDZ173 in Patients With APDS/PASLI [Phase 2, Phase 3]
Phase 2/3 trial results for CDZ173 in APDS/PASLI and CVID have been completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-02-15Clinical Trial Update: A Study to Evaluate the Benefit of RUCONEST® in Subjects Who Experience ADRs Related to IVIG Infusions [Phase 4]
Phase 4 trial evaluating the benefit of RUCONEST® in subjects with adverse events related to IVIG infusions in common variable immunodeficie…
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CLINICAL_TRIALS trial_result · 2020-08-24Clinical Trial Update: Study of Safety, Tolerability, and Efficacy of Ustekinumab for Symptomatic Gastrointestinal Inflammation Associated With Common Variable Immunodeficiency [Phase 1, Phase 2]
Phase 1/2 trial evaluating safety, tolerability, and efficacy of ustekinumab for gastrointestinal inflammation related to common variable im…
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CLINICAL_TRIALS trial_result · 2018-09-12Clinical Trial Update: Pharmacokinetics (PK) and Safety of Subgam-VF in Primary Immunodeficiency Diseases [Phase 3]
Phase 3 trial update reporting pharmacokinetics and safety of Subgam-VF in primary immunodeficiency diseases, including CVID, X-linked agamm…