Colorectal Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-09Clinical Trial Update: A Phase 2 Study of Zanidatamab in Patients With HER2-expressing Tumors [Phase 2]
Jazz Pharmaceuticals is conducting a Phase 2 trial of Zanidatamab in HER2-expressing tumors across multiple cancers. The study is currently …
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Trial of 5-Fluorouracil (5FU)-Based Therapy in Combination With Fruquintinib in Patients With Locally Advanced Unresectable or Metastatic Colorectal Cancer [Phase 2]
Phase 2 clinical trial evaluating a 5-fluorouracil–based regimen in combination with Fruquintinib for metastatic colorectal cancer; the stud…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Designing a Dyad-Based mHealth Intervention to Improve Adherence to Lifestyle Recommendations in Colorectal Cancer Survivors and Their Family Caregivers [NA]
Ongoing study to design a dyad-based mobile health program to improve adherence to lifestyle recommendations among colorectal cancer survivo…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Effects of Berberine on the Human Gut Microbiome [NA]
This clinical trial assesses the effects of berberine on the human gut microbiome in individuals with colorectal adenoma or colorectal cance…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Collagenase Biobank Study
This clinical trial update notes a collagenase biobank study sponsored by the University of Chicago investigating colorectal cancer. The tri…
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CLINICAL_TRIALS withdrawal · 2026-04-09Clinical Trial Update: Colorectal Lesion Evaluation and Appropriate Resolution (CLEAR) Study
The CLEAR study evaluating colorectal lesion evaluation and appropriate resolution has been terminated.
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: The Utility and Feasibility of Mt-sDNA as a Surveillance Procedure in Colorectal Cancer Survivors
Clinical trial update on the utility and feasibility of using Mt-sDNA testing as a surveillance procedure for colorectal cancer survivors, i…
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: GEN1042 Safety Trial and Anti-tumor Activity in Participants With Malignant Solid Tumors [Phase 1, Phase 2]
GEN1042 is being evaluated in a Phase 1/2 safety study with indications across malignant solid tumors, including non-small cell lung cancer,…
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: Dose Escalation and Dose Expansion Study of RMC-6291 Monotherapy in Subjects With Advanced KRASG12C Mutant Solid Tumors [Phase 1]
Phase 1 study update for RMC-6291 monotherapy in KRASG12C-mutant solid tumors, outlining dose-escalation and dose-expansion cohorts in subje…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: EIK1005-002: A Clinical Research Study Evaluating EIK1005, a Werner Helicase Inhibitor, as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors Including Microsatellite Instability High (MSI-H) Tumors [Phase 1, Phase 2]
This clinical trials update notes ongoing Phase 1/2 studies of EIK1005, a Werner helicase inhibitor, as monotherapy and in combination with …
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: ESPERANZA: External Control Arm Study for T-DXd for Patients With HER2 IHC3+ Solid Tumors
ESPERANZA is an external control arm study of trastuzumab deruxtecan (T-DXd) for patients with HER2 IHC3+ solid tumors, sponsored by AstraZe…
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: Comparison of the Left-Lateral Horizontal and Supine Positions for Colonoscopy Intervention: A Randomized Controlled Study [NA]
This randomized controlled trial compared left-lateral horizontal versus supine positioning during colonoscopy to evaluate procedural outcom…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Survivorship Care Plans and Telehealth Education for the Improvement of Access to Cancer Survivorship, the IMPACT Study [NA]
A completed clinical trial evaluating survivorship care plans and telehealth education (the IMPACT Study) aimed at improving access to cance…
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: Fluorescent Probe VGT-309 to ID Cancerous Colorectal Lesions During Augmented Colonoscopy [EARLY_Phase 1]
A early-phase (Phase 1) trial of VGT-309, a fluorescent probe for identifying cancerous colorectal lesions during augmented colonoscopy, has…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, The ERASur Study [Phase 3]
Phase 3 trial update for the ERASur study evaluating adding Total Ablative Therapy to standard systemic therapy in limited metastatic colore…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: A Phase II Study of Sintilimab Combined With Ipilimumab N01, Cetuximab and Dabrafenib in Patients With Microsatellite-Stable, BRAF V600E-Mutated Metastatic Colorectal Cancer [Phase 2]
Phase II study evaluating the combination of Sintilimab, Ipilimumab, Cetuximab, and Dabrafenib in microsatellite-stable, BRAF V600E-mutated …
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: SHR-3821 in Advanced Colorectal Cancer: an Exploratory Study [Phase 2]
A Phase 2 exploratory clinical trial of SHR-3821 for advanced colorectal cancer is described, with the study currently not recruiting.
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Changes in Reproductive and Sexual Health in People With Early Onset Colorectal Cancer
This clinical trial aims to study changes in reproductive and sexual health in people with early-onset colorectal cancer. It is currently re…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: A Study of VET3-TGI in Patients With Solid Tumors [Phase 1]
Phase 1 clinical trial update for VET3-TGI in patients with solid tumors, currently recruiting across multiple cancer types.
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
A clinical trial is enrolling people with and without cancer to collect blood samples and evaluate tests for early cancer detection across m…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: FULIRI Plus Targeted Therapy for First-line Conversion Therapy of Colorectal Cancer Liver Metastases. [Phase 2]
This Phase 2 study investigates FULIRI plus a targeted therapy as first-line conversion treatment for colorectal cancer with liver metastase…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: A Study to Evaluate the Safety, Pharmacokinetics, and Anti-Tumor Activity of VVD-133214 as Monotherapy and in Combination in Participants With Advanced Solid Tumors [Phase 1]
Phase 1 study evaluating the safety, pharmacokinetics, and anti-tumor activity of VVD-133214 as monotherapy and in combination in participan…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: A Study of PF-08046052/SGN-EGFRd2 in Advanced Solid Tumors [Phase 1]
Phase 1 clinical trial update for PF-08046052/SGN-EGFRd2 in advanced solid tumors, including colorectal cancer, non-small cell lung cancer, …
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Raising Awareness of Colorectal Screening in American Indian Communities
A University of Oklahoma-led clinical trial aims to raise awareness of colorectal cancer screening in American Indian communities, with recr…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: A Study of Encorafenib Plus Cetuximab Taken Together With Pembrolizumab Compared to Pembrolizumab Alone in People With Previously Untreated Metastatic Colorectal Cancer [Phase 2]
This is a Phase 2 clinical trial update evaluating three-drug combination therapy (encorafenib, cetuximab, pembrolizumab) versus pembrolizum…