Colorectal Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-10-28Clinical Trial Update: Preoperative Patient Education for Enhanced Recovery After Colon and Rectal Surgery [NA]
A completed clinical trial evaluating preoperative education to support enhanced recovery after colon and rectal cancer surgery.
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EMA withdrawal · 2024-10-24EMA Withdrawn: Onbevzi (bevacizumab) — Samsung Bioepis NL B.V.
The EMA has withdrawn the marketing authorization for Onbevzi (bevacizumab) by Samsung Bioepis NL B.V., across multiple cancer indications. …
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CLINICAL_TRIALS trial_result · 2024-10-24Clinical Trial Update: HIPEC for Peritoneal Carcinomatosis [Phase 2]
This update reports results from a Phase 2 clinical trial evaluating hyperthermic intraperitoneal chemotherapy (HIPEC) for peritoneal carcin…
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CLINICAL_TRIALS research · 2024-10-24Clinical Trial Update: Combination of IV Ascorbic Acid and Adebrelimab in Metastatic Colorectal Cancer [Phase 3]
A Phase 3 clinical trial is evaluating the combination of intravenous ascorbic acid (Vitamin C) and adebrelimab for metastatic colorectal ca…
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CLINICAL_TRIALS research · 2024-10-21Clinical Trial Update: Study to Evaluate the Efficacy of FOLFOX + Panitumumab Followed by FOLFIRI + Bevacizumab (Sequence 1) Versus FOLFOX + Bevacizumab Followed by FOLFIRI + Panitumumab (Sequence 2) in Untreated Patients With Wild-type RAS Metastatic, Primary Left-sided, Unresectable Colorectal Cancer [Phase 3]
Phase 3 trial comparing two sequencing strategies of chemotherapy plus targeted therapy in untreated wild-type RAS metastatic left-sided unr…
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CLINICAL_TRIALS research · 2024-10-21Clinical Trial Update: Study to Evaluate the Efficacy and Safety of Cetuximab in Combination with Encorafenib Plus Binimetinib As Induction Treatment in BRAF V600E Mutated MSS Initially Resectable or Potentially Resectable Advanced Colorectal Cancer [Phase 2]
Phase 2 trial evaluating cetuximab in combination with encorafenib and binimetinib as induction therapy for BRAF V600E-mutated MSS colorecta…
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CLINICAL_TRIALS trial_result · 2024-10-18Clinical Trial Update: Exploratory Study of Rectal Mucus for Diagnosing Disease
Completed exploratory study assessing rectal mucus as a diagnostic approach for colorectal cancer and bowel disease.
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CLINICAL_TRIALS trial_result · 2024-10-18Clinical Trial Update: Study of the Therapeutic Response and Survival of Patients with Metastatic Colorectal Cancer (stage IV) and Treated According to the Guidelines of a Chemosensitivity Test, Oncogramme® (ONCOGRAM) [NA]
A completed clinical trial evaluating the therapeutic response and survival of patients with metastatic colorectal cancer treated according …
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CLINICAL_TRIALS research · 2024-10-17Clinical Trial Update: Circulating Tumour DNA (ctDNA) in Patients With Colorectal Cancer and the Relationship to Imaging Features of Extramural Venous Invasion
A clinical trial update on circulating tumor DNA in colorectal cancer patients and its relationship to imaging features of extramural venous…
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CLINICAL_TRIALS research · 2024-10-17Clinical Trial Update: Reducing Inflammatory Syndrome in Surgery - Colorectal (RISIS-CR) Trial [Phase 3]
The RISIS-CR trial is a Phase 3 study sponsored by National University Hospital, Singapore, investigating strategies to reduce inflammatory …
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CLINICAL_TRIALS research · 2024-10-17Clinical Trial Update: Improving Radical Treatment Through MRI Evaluation of Pelvic Sigmoid Cancers [NA]
A clinical trial from Imperial College London investigates MRI evaluation of pelvic sigmoid cancers to inform surgical treatment; the study …
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CLINICAL_TRIALS research · 2024-10-17Clinical Trial Update: A Clinical Study to Evaluate Efficacy and Safety of Serplulimab（HLX10） Combined With Bevacizumab（HLX04) and Chemotherapy (XELOX) in Patients With Metastatic Colorectal Cancer (mCRC) [Phase 2, Phase 3]
A Phase 2/3 clinical trial evaluating the combination of Serplulimab (HLX10) with Bevacizumab (HLX04) and XELOX chemotherapy in patients wit…
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CLINICAL_TRIALS research · 2024-10-17Clinical Trial Update: Screening for Synchronous Metastases in Colorectal Cancer With DW-MRI (SERENADE) [NA]
An ongoing clinical trial evaluating diffusion-weighted MRI to screen for synchronous metastases in colorectal cancer is currently recruitin…
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CLINICAL_TRIALS research · 2024-10-16Clinical Trial Update: DOSAGE Study: Upfront Dose-Reduced Chemotherapy in Older Patients with Metastatic Colorectal Cancer [Phase 3]
Phase 3 study evaluating upfront dose-reduced chemotherapy in older adults with metastatic colorectal cancer; currently recruiting.
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CLINICAL_TRIALS research · 2024-10-16Clinical Trial Update: Impact of Environmental Factors and Metabolomics on Colorectal Cancer.
This clinical trial update describes ongoing research into how environmental factors and metabolomic profiles may influence colorectal cance…
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CLINICAL_TRIALS research · 2024-10-16Clinical Trial Update: BGT007 Treatment for Recurrent/refractory Gastrointestinal Malignancies [EARLY_Phase 1]
Notes an early Phase 1 trial of BGT007 for recurrent or refractory gastrointestinal cancers, including colorectal and pancreatic cancers, wh…
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CLINICAL_TRIALS other · 2024-10-16Clinical Trial Update: Exercise Preconditioning with Cancer Surgeries [NA]
A University of Virginia study on exercise preconditioning with cancer surgeries has been terminated. No results are provided in this update…
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CLINICAL_TRIALS trial_result · 2024-10-15Clinical Trial Update: Durvalumab for MSI-H or POLE Mutated Metastatic Colorectal Cancer [Phase 2]
Phase 2 trial evaluating Durvalumab for metastatic colorectal cancer with MSI-H or POLE mutations. Results have been posted (completed 2024-…
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CLINICAL_TRIALS trial_result · 2024-10-15Clinical Trial Update: Impact of the COVID-19 Pandemic on Oncologic Outcomes in Colorectal Cancer
This clinical trial update analyzes how the COVID-19 pandemic affected oncologic outcomes in patients with colorectal cancer.
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CLINICAL_TRIALS trial_result · 2024-10-15Clinical Trial Update: A Phase 2 Randomized, Open-Label Study of RRx-001 vs Regorafenib in Subjects With Metastatic Colorectal Cancer [Phase 2]
Phase 2 randomized, open-label trial comparing RRx-001 to regorafenib in metastatic colorectal cancer has completed and posted results.
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CLINICAL_TRIALS research · 2024-10-15Clinical Trial Update: Bevacizumab-based Chemotherapy Adapted to Bevacizumab Pharmacokinetics in 1st-line Treatment [Phase 3]
This Phase 3 trial evaluates bevacizumab-based chemotherapy adapted to bevacizumab pharmacokinetics for first-line treatment of unresectable…
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CLINICAL_TRIALS trial_result · 2024-10-15Clinical Trial Update: Safety and Efficacy of Pembrolizumab (MK-3475) Plus Binimetinib Alone or Pembrolizumab Plus Chemotherapy With or Without Binimetinib in Metastatic Colorectal Cancer (mCRC) Participants (MK-3475-651/KEYNOTE-651) [Phase 1]
Phase 1 study assessing pembrolizumab with binimetinib, alone or with chemotherapy (with or without binimetinib), in metastatic colorectal c…
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CLINICAL_TRIALS trial_result · 2024-10-15Clinical Trial Update: Adaptive Intervention to Maximize Colorectal Screening in Safety Net Populations [NA]
A clinical trial update describes an adaptive intervention to maximize colorectal cancer screening in safety-net populations. The study, led…
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CLINICAL_TRIALS trial_result · 2024-10-15Clinical Trial Update: Evaluate the Efficacy, Safety and Tolerability of HLX26 and Serplulimab in Patients with MCRC [Phase 2]
Phase 2 trial evaluating HLX26 in combination with serplulimab for metastatic colorectal cancer has been terminated. No efficacy or safety r…
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CLINICAL_TRIALS trial_result · 2024-10-15Clinical Trial Update: Technical Feasibility Evaluation of Mucosal Staining During Colon Capsule Endoscopy (CCE) Procedure in Colorectal Cancer (CRC) High Risk Population, When Using MB-MMX [NA]
A completed clinical trial evaluating the technical feasibility of MB-MMX mucosal staining during colon capsule endoscopy in a high-risk col…