Colorectal Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-01-07Clinical Trial Update: TAS102 in Combination With NAL-IRI in Advanced GI Cancers [Phase 1, Phase 2]
This document provides an update on an ongoing Phase 1/2 clinical trial evaluating the combination of TAS-102 with nanoliposomal irinotecan …
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CLINICAL_TRIALS trial_result · 2025-01-06Clinical Trial Update: Promoting Informed Decisions About Cancer Screening in Older Adults [NA]
Completed trial at Massachusetts General Hospital evaluating how to promote informed decisions about colorectal cancer screening in older ad…
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CLINICAL_TRIALS research · 2025-01-06Clinical Trial Update: Locally ablatIVe thErapy for oLigo-progressive gastrOintestiNal maliGnancies (LIVELONG) [NA]
The LIVELONG trial from University of California, Davis is an ongoing study evaluating locally ablative therapy for oligoprogressive gastroi…
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CLINICAL_TRIALS trial_result · 2025-01-03Clinical Trial Update: Dorsal Vetilation and PPCs in Colorectal Cancer Surgery Patients
The completed clinical trial NCT06662799 evaluated ventilation strategy and postoperative pulmonary complications in colorectal cancer surge…
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CLINICAL_TRIALS research · 2025-01-01Clinical Trial Update: Gut Microbiome Dynamics in Metastasized or Irresectable Colorectal Cancer
A clinical trial is investigating gut microbiome dynamics in patients with metastatic or unresectable colorectal cancer and is currently rec…
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CLINICAL_TRIALS research · 2025-01-01Clinical Trial Update: Molecular Characterisation of Colorectal Cancer Peritoneal Metastases
A clinical trial to molecularly characterize peritoneal metastases from colorectal cancer, currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-12-31Clinical Trial Update: A Clinical Study to Compare the Efficacy, Safety and Immunogenicity of HLX04 and Bevacizumab Combined XELOX or mFOLFOX6 in the First-line Treatment of mCRC [Phase 3]
A Phase 3 trial compared HLX04 to Bevacizumab, each given with XELOX or mFOLFOX6 as first-line therapy in metastatic colorectal cancer; the …
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CLINICAL_TRIALS trial_result · 2024-12-31Clinical Trial Update: An Open-label, Multicenter, Single-arm Clinical Study on the Use of Doxorubicin Liposome in Combination With CapOX and Bevacizumab Regimen for First-line Treatment of Advanced Colorectal Adenocarcinoma With SMAD4R361H/C Mutation. [Phase 1, Phase 2]
An open-label, multicenter, single-arm Phase 1/2 study evaluating a doxorubicin liposome-containing regimen with CapOX and bevacizumab as fi…
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CLINICAL_TRIALS trial_result · 2024-12-31Clinical Trial Update: The Role of Natural Orifice Specimen Extraction Surgery (NOSES) in Treating Right-sided Colon Cancer [NA]
A clinical trial evaluating Natural Orifice Specimen Extraction Surgery (NOSES) for right-sided colon cancer has completed.
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CLINICAL_TRIALS withdrawal · 2024-12-31Clinical Trial Update: Study of an Individualized Vaccine Targeting Neoantigens in Combination With Immune Checkpoint Blockade for Patients With Colon Cancer [Phase 2]
Phase 2 study evaluating an individualized neoantigen cancer vaccine in combination with an immune checkpoint blocker for colorectal cancer …
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CLINICAL_TRIALS research · 2024-12-30Clinical Trial Update: Colorectal Omics and OfCS Proteoglycans
A recruiting clinical trial evaluating colorectal omics and OfCS proteoglycans in colorectal cancer, diverticulitis, and inflammatory bowel …
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CLINICAL_TRIALS research · 2024-12-30Clinical Trial Update: Neoantigen-based Peptide Vaccine and Conventional Third-line Therapy for CRC Progressed After Second-line Treatment [NA]
This ongoing study investigates a neoantigen-based peptide vaccine combined with conventional third-line therapy for colorectal cancer that …
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CLINICAL_TRIALS research · 2024-12-30Clinical Trial Update: Neoantigen-based Peptide Vaccine and Conventional Second-line Therapy for CRC Progressed After First-line Treatment [NA]
ClinicalTrials.gov entry describing a study of a neoantigen-based peptide vaccine plus conventional second-line therapy for colorectal cance…
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CLINICAL_TRIALS research · 2024-12-30Clinical Trial Update: Neoantigen-loaded DC Vaccine and Conventional Second-line Therapy for CRC Progressed After First-line Treatment [NA]
A clinical trial is recruiting to evaluate a neoantigen-loaded dendritic cell vaccine in combination with conventional second-line therapy f…
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CLINICAL_TRIALS other · 2024-12-30Clinical Trial Update: Expanded Access Program (EAP) Designed to Provide Access to Botensilimab and Balstilimab Before Regulatory Approval
Agenus has launched an Expanded Access Program to provide Botensilimab and Balstilimab to patients before regulatory approval. The program t…
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CLINICAL_TRIALS research · 2024-12-30Clinical Trial Update: Neoantigen-loaded DC Vaccine and Conventional Third-line Therapy for CRC Progressed After Second-line Treatment [NA]
This clinical trial evaluates a neoantigen-loaded dendritic cell vaccine plus conventional third-line therapy for colorectal cancer that pro…
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CLINICAL_TRIALS trial_result · 2024-12-27Clinical Trial Update: Gut Microbiome and Colorectal Cancer
A completed clinical trial evaluating the relationship between the gut microbiome and colorectal cancer, sponsored by Heliopolis University.
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CLINICAL_TRIALS research · 2024-12-27Clinical Trial Update: Serum MicroRNAs as Diagnostic Biomarkers of Colorectal Cancer
This clinical trial evaluates serum microRNAs as diagnostic biomarkers for colorectal cancer, with recruitment not yet started.
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CLINICAL_TRIALS trial_result · 2024-12-27Clinical Trial Update: Standard Therapy With or Without Surgery and Mitomycin C in Treating Patients With Advanced Limited Peritoneal Dissemination of Colon Cancer [Phase 3]
A Phase 3 trial evaluating standard therapy with or without surgery plus Mitomycin C for advanced limited peritoneal dissemination of colon …
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CLINICAL_TRIALS trial_result · 2024-12-27Clinical Trial Update: Dasatinib for the Prevention of Oxaliplatin-Induced Neuropathy in Patients With Metastatic Gastrointestinal Cancer Receiving FOLFOX Chemotherapy With or Without Bevacizumab [Phase 1]
Phase 1 trial evaluating dasatinib to prevent oxaliplatin-induced neuropathy in patients with metastatic gastrointestinal cancers receiving …
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CLINICAL_TRIALS trial_result · 2024-12-27Clinical Trial Update: Flatbush FHC Proactive Colorectal Cancer Screening and Navigation [NA]
Completed clinical trial evaluating proactive colorectal cancer screening and navigation at Flatbush FHC; results have been posted.
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CLINICAL_TRIALS research · 2024-12-27Clinical Trial Update: A Study on Treatment for Patients With BRAFV600E Mutant Metastatic Colorectal Cancer (mCRC)
This clinical trial update describes a study investigating treatment for BRAFV600E-mutant metastatic colorectal cancer, which is currently r…
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CLINICAL_TRIALS research · 2024-12-27Clinical Trial Update: Survival Benefit of Compound Kushen Injection in the Treatment of Advanced Colorectal Cancer [Phase 4]
Phase 4 trial evaluating Compound Kushen Injection for advanced colorectal cancer is currently recruiting, with the study seeking potential …
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CLINICAL_TRIALS trial_result · 2024-12-27Clinical Trial Update: Multivisceral Radical Resection for Surgical T4b Colorectal Cancer: Propensity Score-matched Study Comparing the the Laparoscopic and Open Approaches
A completed propensity score-matched study compares laparoscopic versus open multivisceral radical resection for surgical T4b colorectal can…
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CLINICAL_TRIALS research · 2024-12-27Clinical Trial Update: Exploring the Treatment Duration of PD-1 Neoadjuvant Therapy in Stage II-III dMMR Rectal Cancer
This entry updates a clinical trial evaluating how long PD-1 neoadjuvant therapy should be given for stage II-III mismatch repair-deficient …