Colorectal Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-01-28Clinical Trial Update: Sequential Immunochemotherapy Treatment with Pembrolizumab Plus Dendritic Cell (DC) Vaccine Followed by Trifluridine/Tipiracil Plus Bevacizumab in Refractory Mismatch-repair-proficient (pMMR) or Microsatellite-stable (MSS) Metastatic Colorectal Cancer [Phase 2]
Phase 2 clinical trial of sequential immunochemotherapy in refractory metastatic colorectal cancer, starting with pembrolizumab plus a dendr…
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CLINICAL_TRIALS trial_result · 2025-01-28Clinical Trial Update: Calcium: Magnesium Balance, Microbiota, and Necroptosis and Inflammation [NA]
A completed Vanderbilt study investigated calcium and magnesium balance, gut microbiota, necroptosis, and inflammation in colorectal cancer;…
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CLINICAL_TRIALS research · 2025-01-28Clinical Trial Update: Pre- and Post-operative TEG Indices in Patients With or Without Adenocarcinoma Undergoing Surgical Resection
A clinical trial update investigating pre- and post-operative thromboelastography (TEG) indices in patients undergoing surgical resection, c…
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CLINICAL_TRIALS research · 2025-01-28Clinical Trial Update: Evaluation of Irinotecan Liposome (II) Combined With 5-FU, LV, and Bevacizumab for mCRC [Phase 2]
This clinical trial update reports a Phase 2 study evaluating a combination of irinotecan liposome with 5-fluorouracil, leucovorin, and beva…
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FDA approval · 2025-01-27FDA Approved: CYRAMZA — Supplemental Application (Eli Lilly and Company)
FDA approved a supplemental application for CYRAMZA (ramucirumab) from Eli Lilly and Company.
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CLINICAL_TRIALS trial_result · 2025-01-27Clinical Trial Update: A Randomized, 2x2 Factorial Design Biomarker Prevention Trial of Low-dose ASA and Metformin in Stage I-III Crc Patients [Phase 2]
A Phase 2 randomized 2x2 factorial trial evaluating low-dose aspirin and metformin as biomarker-prevention strategies in patients with Stage…
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CLINICAL_TRIALS trial_result · 2025-01-27Clinical Trial Update: Study on the Applicability of CCR Criteria in Rectal Cancer
A clinical trial investigating the applicability of CCR criteria in rectal/colorectal cancer has completed.
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FDA approval · 2025-01-27FDA Approved: OXALIPLATIN — Original Application (Camber Pharmaceuticals, Inc.)
FDA approved Camber Pharmaceuticals' Oxaliplatin as an original application generic; Oxaliplatin is a platinum-based chemotherapy used for c…
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CLINICAL_TRIALS research · 2025-01-27Clinical Trial Update: Study on the Impact of a Modified Mediterranean Diet, in Patients With Colorectal Cancer Undergoing Active Medical Oncology Treatment [NA]
Clinical trial update on a modified Mediterranean diet for colorectal cancer patients undergoing active oncology treatment; the study is cur…
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CLINICAL_TRIALS trial_result · 2025-01-24Clinical Trial Update: Scottish Vitamin D Intervention Study [NA]
Clinical trial update for a Vitamin D intervention study in colorectal cancer. The trial is completed and results were posted on 2025-01-24.
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CLINICAL_TRIALS trial_result · 2025-01-24Clinical Trial Update: Health Care Coach Support in Reducing Acute Care Use and Cost in Patients With Cancer [NA]
This update reports the completion of a clinical trial evaluating health care coach support to reduce acute care use and costs in cancer pat…
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CLINICAL_TRIALS withdrawal · 2025-01-24Clinical Trial Update: Combination Therapy of RMC-4630 and LY3214996 in Metastatic KRAS Mutant Cancers [Phase 1]
Phase 1 trial evaluating the combination of RMC-4630 and LY3214996 in metastatic KRAS-mutant cancers has been terminated. The study encompas…
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CLINICAL_TRIALS research · 2025-01-24Clinical Trial Update: ProSight: a Multi-centre Interventional Study Evaluating MCED in Asymptomatic Population [NA]
This clinical trial update describes the ProSight multi-centre interventional study evaluating a multi-cancer early detection (MCED) test in…
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CLINICAL_TRIALS research · 2025-01-24Clinical Trial Update: Artificial Intelligence-Assisted Colonoscopy in Colorectal Cancer Screening in a General Hospital [NA]
This clinical trial update describes an AI-assisted colonoscopy study for colorectal cancer screening at a general hospital. The study statu…
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CLINICAL_TRIALS research · 2025-01-23Clinical Trial Update: Study of CBX-12 in Subjects With Advanced or Metastatic Refractory Solid Tumors [Phase 1, Phase 2]
Phase 1/2 study of CBX-12 in adults with advanced or metastatic refractory solid tumors. The trial includes multiple cancer types and is cur…
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CLINICAL_TRIALS research · 2025-01-23Clinical Trial Update: Multidimensional Examination of Patients with Colorectal and Anal Cancer
An observational clinical trial update from the University of Pecs outlines a multidimensional examination of patients with colorectal cance…
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CLINICAL_TRIALS trial_result · 2025-01-22Clinical Trial Update: Comparative Effectiveness of Split-Dose Colonoscopy Bowel Preparation Regimens [Phase 4]
Phase 4 trial comparing the effectiveness and tolerability of split-dose bowel preparation regimens prior to colonoscopy; results have been …
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CLINICAL_TRIALS research · 2025-01-22Clinical Trial Update: Fruquintinib Plus S-1 and Raltitrexed (RSF) for MCRC [Phase 2]
This update describes a Phase 2 trial of Fruquintinib plus S-1 and Raltitrexed (RSF) for metastatic colorectal cancer, which is currently re…
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CLINICAL_TRIALS research · 2025-01-22Clinical Trial Update: The Role of 18F-FDG and 68Ga-FAPI PET/CT in the Diagnosis and the Efficacy Evaluation of Advanced Colorectal Cancer (peritoneal Metastasis With/without Other Metastases)
This document describes a recruiting clinical trial evaluating PET/CT imaging with 18F-FDG and 68Ga-FAPI tracers to diagnose and evaluate tr…
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CLINICAL_TRIALS research · 2025-01-22Clinical Trial Update: Ga-68-FAPI-46 PET for CRC Recurrence Detection in Elevated CEA [NA]
Clinical trial evaluating Ga-68-FAPI-46 PET imaging for detecting colorectal cancer recurrence in patients with elevated CEA; currently recr…
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CLINICAL_TRIALS research · 2025-01-22Clinical Trial Update: Safety and Efficacy of PD-1 ± mFOLFOX6 Neoadjuvant Therapy in Local Advanced sMPCC [Phase 2]
Phase 2 clinical trial evaluating PD-1 inhibitor with or without mFOLFOX6 as neoadjuvant therapy for locally advanced colorectal cancer with…
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CLINICAL_TRIALS research · 2025-01-22Clinical Trial Update: Development of Organoids From Primary Colorectal Tumors and Synchronous Liver Metastases
The document reports a clinical trial to develop organoids from primary colorectal tumors and synchronous liver metastases, with recruitment…
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CLINICAL_TRIALS trial_result · 2025-01-22Clinical Trial Update: mFOLFOX6+Bevacizumab+PD-1 Monoclonal Antibody in Local Advanced MSS CRC [Phase 2]
Phase 2 study of mFOLFOX6 plus Bevacizumab and a PD-1 monoclonal antibody in locally advanced microsatellite-stable colorectal cancer has co…
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CLINICAL_TRIALS research · 2025-01-22Clinical Trial Update: Proteomic Analysis of Patients Undergoing Bariatric Surgery [NA]
A clinical trial update describing a proteomic analysis of bariatric surgery patients, sponsored by Universidade Federal de Pernambuco, with…
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CLINICAL_TRIALS trial_result · 2025-01-21Clinical Trial Update: Colorectal Cancer Screening in Xinxiang City
A clinical trial evaluating colorectal cancer screening in Xinxiang City has completed.