Colorectal Cancer

• CLINICAL_TRIALS trial_result · 2025-02-14
  Clinical Trial Update: Live Biotherapeutic Product GB104 Phase 1 Study in Colorectal Cancer [Phase 1]

  A Phase 1 study of the live biotherapeutic GB104 in colorectal cancer has completed.

• CLINICAL_TRIALS other · 2025-02-14
  Clinical Trial Update: Lifestyle Intervention Among Participants of the French Colorectal Cancer Screening Program (LIFE-SCREEN) [NA]

  This clinical trial update describes the LIFE-SCREEN study, which examines lifestyle intervention among participants in the French colorecta…

• CLINICAL_TRIALS research · 2025-02-13
  Clinical Trial Update: Metformin for the Treatment of mCRC Patients Undergoing FOLFIRI Plus Target Therapy [Phase 2]

  A Phase 2 clinical trial is evaluating metformin in combination with FOLFIRI plus targeted therapy for metastatic colorectal cancer. Recruit…

• CLINICAL_TRIALS research · 2025-02-13
  Clinical Trial Update: ARTEMIS-102: HS-20093 Combinations in Patients with Advanced Metastatic Colorectal Cancer [Phase 1]

  Ongoing Phase 1 clinical trial ARTEMIS-102 evaluating HS-20093 combinations in patients with advanced metastatic colorectal cancer; the stud…

• CLINICAL_TRIALS trial_result · 2025-02-13
  Clinical Trial Update: Feasibility of 2 Interventions to Reduce Fatigue in Patients With Chemotherapy for Metastatic Colorectal Cancer [NA]

  This clinical trial evaluated two interventions to reduce fatigue in patients undergoing chemotherapy for metastatic colorectal cancer; the …

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• CLINICAL_TRIALS research · 2025-02-13
  Clinical Trial Update: Effects of Endocrine Disruptors on the Gut Microbiota and Assessment of Their Impact on Colorectal Cancer Development (PERMICA) [NA]

  A recruiting clinical trial examining how endocrine disruptors affect gut microbiota and their potential role in colorectal cancer developme…

• CLINICAL_TRIALS trial_result · 2025-02-13
  Clinical Trial Update: Education Intervention in Patients with Rash Due to Epidermal Growth Factor Receptor (EGFR) Treatment. [NA]

  This clinical trial update describes an education intervention aimed at helping patients manage rash associated with epidermal growth factor…

• CLINICAL_TRIALS research · 2025-02-13
  Clinical Trial Update: Effectiveness of a Mobile Health Management Program for Colorectal Cancer Survivors With Chronic Conditions [NA]

  This clinical trial update describes the effectiveness of a mobile health management program for colorectal cancer survivors with chronic co…

• CLINICAL_TRIALS research · 2025-02-12
  Clinical Trial Update: A Study of IBI363 in Combination With Bevacizumab or Furuitinib in Subjects With Advanced Colorectal Cancer [Phase 1]

  Phase 1 clinical trial of IBI363 in combination with Bevacizumab or Furuitinib for advanced colorectal cancer, currently recruiting.

• CLINICAL_TRIALS research · 2025-02-12
  Clinical Trial Update: Development of Clinical and Biological Database in Colorectal Cancer [NA]

  A completed clinical and biological database development project focused on colorectal cancer (metastatic colon cancer).

• CLINICAL_TRIALS trial_result · 2025-02-12
  Clinical Trial Update: LYT-200 Alone and in Combination With Chemotherapy or Tislelizumab in Patients With Locally Advanced or Metastatic Solid Tumors [Phase 1, Phase 2]

  Phase 1/2 clinical trial update of LYT-200 as a single agent and in combination with chemotherapy or tislelizumab in locally advanced or met…

• CLINICAL_TRIALS research · 2025-02-12
  Clinical Trial Update: The Study on the Efficacy and Safety of Lactobacillus Johnsonii in Combination with CapeOX and Pembrolizumab for the Treatment of MSS/pMMR Metastatic Colorectal Cancer. [NA]

  A clinical trial update describing a study of Lactobacillus Johnsonii with CapeOX and Pembrolizumab for MSS/pMMR metastatic colorectal cance…

• CLINICAL_TRIALS research · 2025-02-12
  Clinical Trial Update: Advances in Imaging to Assess Response in Rectal Cancer

  This clinical trial update describes advances in imaging techniques to assess treatment response in rectal cancer and notes that the study i…

• CLINICAL_TRIALS research · 2025-02-12
  Clinical Trial Update: Clinical Database of Colorectal Robotic Surgery

  This clinical trial database entry for colorectal robotic surgery, sponsored by Institut du Cancer de Montpellier – Val d'Aurelle, lists col…

• CLINICAL_TRIALS trial_result · 2025-02-12
  Clinical Trial Update: Encorafenib + Cetuximab Beyond Progression in Combination With FOLFIRI in Patients With BRAF V600E Mutated Metastatic Colorectal Cancer Progressing on Encorafenib + Cetuximab. [Phase 2]

  Phase 2 clinical trial evaluating the addition of FOLFIRI after progression on encorafenib plus cetuximab in patients with BRAF V600E-mutate…

• CLINICAL_TRIALS research · 2025-02-11
  Clinical Trial Update: Recurrence Rate After Endoscopic Resection of , Laterally Spreading Tumor Granular Type (LST-G) of the Colon and Rectum: Endoscopic Mucosal Resection Vs. Endoscopic Submucosal Dissection [NA]

  This clinical trial compares endoscopic mucosal resection (EMR) with endoscopic submucosal dissection (ESD) to evaluate recurrence after res…

• CLINICAL_TRIALS research · 2025-02-11
  Clinical Trial Update: Phase 3 Study of MRTX849 With Cetuximab vs Chemotherapy in Patients With Advanced Colorectal Cancer With KRAS G12C Mutation (KRYSTAL-10) [Phase 3]

  Phase 3 KRYSTAL-10 trial evaluating MRTX849 (adagrasib) with cetuximab versus chemotherapy in advanced/metastatic KRAS G12C-mutant colorecta…

• CLINICAL_TRIALS trial_result · 2025-02-11
  Clinical Trial Update: Selumetinib and Cyclosporine in Treating Patients With Advanced Solid Tumors or Advanced or Metastatic Colorectal Cancer [Phase 1]

  The document reports completion of a Phase 1 trial evaluating selumetinib in combination with cyclosporine for advanced solid tumors or adva…

• CLINICAL_TRIALS research · 2025-02-11
  Clinical Trial Update: Phase I/II Clinical Study to Evaluate VB15010 Tablets in Patients With Advanced Solid Tumors [Phase 1, Phase 2]

  Phase I/II trial update for VB15010 tablets in advanced solid tumors; the study is currently recruiting across multiple cancer types.

• CLINICAL_TRIALS trial_result · 2025-02-11
  Clinical Trial Update: Risk of Metachronous Findings After Detection of Serrated Lesions and High-grade Dysplasia With Surveillance Delay [NA]

  This clinical trial update notes a recruiting study from CHUM examining the risk of metachronous findings after detection of serrated lesion…

• CLINICAL_TRIALS research · 2025-02-11
  Clinical Trial Update: Complete Closure After Endoscopic Mucosal Resection of Large Non-Pedunculated Colorectal Polyps [NA]

  The trial update indicates ongoing recruitment for a study evaluating complete closure after endoscopic mucosal resection of large non-pedun…

• CLINICAL_TRIALS trial_result · 2025-02-10
  Clinical Trial Update: Colorectal Cancer Survivor Symptom Management [NA]

  This entry reports the completion of a clinical trial investigating symptom management for colorectal cancer survivors. The provided snippet…

• CLINICAL_TRIALS trial_result · 2025-02-07
  Clinical Trial Update: A Study of SGN-STNV in Advanced Solid Tumors [Phase 1]

  Seagen's Phase 1 study of SGN-STNV in advanced solid tumors has been terminated.

• CLINICAL_TRIALS trial_result · 2025-02-07
  Clinical Trial Update: Study of Covalent Menin Inhibitor BMF-219 in Adult Patients With KRAS Driven Non-Small Cell Lung Cancer, Pancreatic Cancer, and Colorectal Cancer [Phase 1]

  A Phase 1 trial of Biomea Fusion's covalent menin inhibitor BMF-219 in KRAS-driven non-small cell lung cancer, pancreatic cancer, and colore…

• CLINICAL_TRIALS trial_result · 2025-02-07
  Clinical Trial Update: Phase IIa Study of Nimotuzumab to Treat Colorectal Cancer [Phase 1, Phase 2]

  The document reports completion of a Phase 1/Phase 2a study evaluating Nimotuzumab for colorectal cancer.