Colorectal Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-03-06Clinical Trial Update: Trial of Gum Chewing to Enhance the Restoration of Intestinal Motility in Colorectal Cancer Surgery [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial is investigating whether chewing gum can enhance restoration of intestinal motility after colorectal cancer…
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CLINICAL_TRIALS research · 2025-03-05Clinical Trial Update: Advanced Endo-therapeutic Procedure : Registry-based Observational Study
Registry-based observational study evaluating advanced endo-therapeutic procedures for Zenker's diverticulum and colorectal conditions; recr…
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CLINICAL_TRIALS research · 2025-03-05Clinical Trial Update: Chidamide in Combination With PD-1 Inhibitor, Bevacizumab, and XELOX for Metastatic Colorectal Cancer [Phase 2]
A Phase 2 trial evaluating chidamide in combination with a PD-1 inhibitor, bevacizumab, and XELOX for metastatic colorectal cancer. The stud…
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CLINICAL_TRIALS research · 2025-03-05Clinical Trial Update: Clinical Performance of the Mainz Biomed Colorectal Cancer Screening Test for Colorectal Cancer and Advanced Adenoma
A clinical trial update notes the Mainz Biomed colorectal cancer screening test being evaluated for detecting colorectal cancer and advanced…
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CLINICAL_TRIALS research · 2025-03-05Clinical Trial Update: Real-World Study of Chidamide Combined With PD-(L)1 Inhibitors and Anti-Angiogenic Therapy for Advanced MSS-Type Colorectal Cancer
This clinical trial update describes a real-world study evaluating chidamide in combination with PD-1/PD-L1 inhibitors and anti-angiogenic t…
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CLINICAL_TRIALS trial_result · 2025-03-04Clinical Trial Update: Onvansertib in Combination With FOLFIRI and Bevacizumab for Second Line Treatment of Metastatic Colorectal Cancer Patients With a KRAS Mutation [Phase 1, Phase 2]
Phase 1/2 trial evaluating Onvansertib plus FOLFIRI and Bevacizumab for second-line metastatic colorectal cancer with KRAS mutation has comp…
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CLINICAL_TRIALS trial_result · 2025-03-04Clinical Trial Update: Aspirin in Preventing Colorectal Cancer in Patients With Colorectal Adenoma [Phase 2]
A Phase 2 clinical trial is evaluating aspirin for prevention of colorectal cancer in people with colorectal adenoma. Results have been post…
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CLINICAL_TRIALS research · 2025-03-04Clinical Trial Update: Induction Treatment for Initially Unresectable Colorectal Liver Metastases: Combined Hepatic Arterial Infusion Pump Therapy With Systemic Therapy [Phase 3]
Phase 3 clinical trial evaluating induction treatment for initially unresectable colorectal liver metastases using combined hepatic arterial…
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CLINICAL_TRIALS research · 2025-03-04Clinical Trial Update: The Role of Coenzyme Q10 in the Prophylaxis of Oxaliplatin Induced Peripheral Neuropathy in Patients With Colorectal Cancer [Phase 1]
A Phase 1 trial is evaluating whether Coenzyme Q10 can prevent oxaliplatin-induced peripheral neuropathy in colorectal cancer patients and i…
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CLINICAL_TRIALS research · 2025-03-04Clinical Trial Update: An Open-label, Single-arm, Multicenter Phase II Study to Evaluate the Efficacy of Amivantamab in Combination With FOLFIRI as a Second-line Treatment in Patients With RAS/BRAF Wild-type Advanced Colorectal Cancer Progressing on Prior Anti-EGFR Based Treatment. [Phase 2]
Phase II open-label, single-arm multicenter study evaluating amivantamab in combination with FOLFIRI as second-line treatment for RAS/BRAF w…
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CLINICAL_TRIALS research · 2025-03-03Clinical Trial Update: Neoadjuvant Therapy for Locally Advanced Rectal Cancer [EARLY_Phase 1]
This document provides a clinical trial update for neoadjuvant therapy in locally advanced rectal cancer. The trial is at EARLY Phase 1, spo…
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CLINICAL_TRIALS trial_result · 2025-02-28Clinical Trial Update: Pembrolizumab, Capecitabine, and Bevacizumab for Treating Colorectal Cancer [Phase 2]
A Phase II trial evaluating the combination of pembrolizumab, capecitabine, and bevacizumab for microsatellite-stable, mismatch repair profi…
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CLINICAL_TRIALS research · 2025-02-28Clinical Trial Update: Personalized DC Vaccine for Postoperative Cancer [Phase 1]
A Phase 1 clinical trial evaluating a personalized dendritic cell vaccine for postoperative gastric cancer and hepatocellular carcinoma is c…
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CLINICAL_TRIALS research · 2025-02-27Clinical Trial Update: Assessment of Direct Biomarkers of Aspirin Action to Develop a Precision Chemoprevention Therapy of Colorectal Cancer [Phase 2]
Phase 2 clinical trial investigating direct biomarkers of aspirin action to develop a precision chemoprevention therapy for colorectal cance…
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CLINICAL_TRIALS research · 2025-02-27Clinical Trial Update: Irinotecan Liposomes Combined with Cetuximab + Vermofenib in First-line Failure of Advanced Colorectal Cancer [Phase 2]
This Phase 2 trial investigates irinotecan liposomes with cetuximab and vermofenib in advanced metastatic colorectal cancer; the study is cu…
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CLINICAL_TRIALS research · 2025-02-27Clinical Trial Update: Multicenter Retrospective Study on Optimizing Combination Immunotherapy Strategies in MSS/MSI-L/pMMR Advanced Colorectal Cancer
A multicenter retrospective study is investigating optimized combination immunotherapy strategies for MSS/MSI-L/pMMR advanced colorectal can…
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CLINICAL_TRIALS research · 2025-02-27Clinical Trial Update: Evaluation of PreveCol's Efficiency As a Second Line Method for the Early Colorectal Cancer Detection [NA]
An ongoing clinical trial is evaluating PreveCol as a second-line method for early detection of colorectal cancer and is currently recruitin…
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CLINICAL_TRIALS research · 2025-02-27Clinical Trial Update: Effects of UNICLA-A2 Dairy Products on Patients At High-risk of Colorectal Cancer Development [NA]
A clinical trial is evaluating UNICLA-A2 dairy products in people at high risk of developing colorectal cancer, including those with colorec…
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CLINICAL_TRIALS trial_result · 2025-02-26Clinical Trial Update: The BurnAlong Pilot Study for Adolescent and Young Adult Cancer Survivors [NA]
Completed update for the BurnAlong Pilot Study evaluating a program for adolescent and young adult cancer survivors. The study spans multipl…
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CLINICAL_TRIALS trial_result · 2025-02-26Clinical Trial Update: An Observational Study to Learn More About the Long-Term Responses to Treatment With Regorafenib in Patients With Metastatic Colorectal Cancer in the United States
This clinical trial update describes an observational study assessing long-term responses to regorafenib in adults with metastatic colorecta…
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CLINICAL_TRIALS trial_result · 2025-02-25Clinical Trial Update: Impact of Vascular Endothelial Growth Factor Gene Polymorphisms on Bevacizumab Efficacy in a Sample of Iraqi Patients With Metastatic Colorectal Cancer [Phase 4]
A Phase 4 study in metastatic colorectal cancer examines how VEGF gene polymorphisms influence bevacizumab efficacy in Iraqi patients.
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CLINICAL_TRIALS withdrawal · 2025-02-25Clinical Trial Update: Study of rSIFN-co for Patients With Advanced Solid Tumors [Phase 1]
A Phase 1 clinical trial of rSIFN-co for advanced solid tumors has been terminated, involving malignancies including melanoma, kidney cancer…
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CLINICAL_TRIALS research · 2025-02-25Clinical Trial Update: The Use of Indocyanine Green Near-infrared Fluorescence for Bowel Perfusion Quantitative Assessment in Order to Prevent Anastomotic Leakage in Colorectal Surgery [Phase 3]
This update describes a Phase 3 clinical trial evaluating indocyanine green near-infrared fluorescence to quantify bowel perfusion during co…
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CLINICAL_TRIALS trial_result · 2025-02-24Clinical Trial Update: Clinical Validation of PolyDeep: an Artificial Intelligence-based Computer-aided Polyp Detection (CADe) and Characterization (CADx) System. Polydeep Advance 3 [NA]
This document reports completion of a clinical validation trial for PolyDeep, an AI-based polyp detection and characterization system for co…
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CLINICAL_TRIALS trial_result · 2025-02-24Clinical Trial Update: Clinical Validation of Polydeep: an Artificial Intelligence-based Computer-aided Polyp Detection (CADe) and Characterization (CADx) System [NA]
Clinical validation of Polydeep, an AI-based CADe/CADx system for detecting and characterizing colorectal polyps, has completed. The study p…