Colorectal Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-03-20Clinical Trial Update: Diagnostic Value of Diffusion-weighted Magnetic Resonance in High-risk Colorectal and Appendiceal Neoplasms [NA]
Clinical trial update evaluating the diagnostic value of diffusion-weighted MRI for high-risk colorectal and appendiceal neoplasms; the stud…
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CLINICAL_TRIALS trial_result · 2025-03-19Clinical Trial Update: Hepatic Arterial Infusion With Floxuridine and Dexamethasone Combination With Chemotherapy With/Without Bevacizumab for Hepatic Metastases From Colorectal Cancer [Phase 2]
Phase 2 trial evaluating hepatic arterial infusion with floxuridine and dexamethasone, with or without bevacizumab, for hepatic metastases f…
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CLINICAL_TRIALS trial_result · 2025-03-19Clinical Trial Update: Study of the Safety, Tolerability and Efficacy of KPT-8602 in Participants With Relapsed/Refractory Cancer Indications [Phase 1, Phase 2]
A Phase 1/2 clinical trial of KPT-8602 (eltanexor) in participants with relapsed/refractory cancer indications completed, evaluating safety,…
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CLINICAL_TRIALS trial_result · 2025-03-19Clinical Trial Update: Safety/Efficacy Study of Imprime PGG With Cetuximab in Patients With Recurrent/Progressive Colorectal Carcinoma [Phase 1, Phase 2]
A phase 1/2 trial evaluating safety and preliminary efficacy of Imprime PGG in combination with cetuximab in patients with recurrent or prog…
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CLINICAL_TRIALS trial_result · 2025-03-19Clinical Trial Update: Relative Bioavailability/Bioequivalence of Different Formulations of Selinexor, the Impact of Hepatic Impairment on Selinexor Pharmacokinetics, Tolerability and Antitumor Activity of Selinexor Combination Treatment [Phase 1, Phase 2]
The update reports on the relative bioavailability/bioequivalence of different selinexor formulations, the impact of hepatic impairment on s…
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CLINICAL_TRIALS research · 2025-03-19Clinical Trial Update: Cadonilimab for PD-1/PD-L1 Blockade-refractory, MSI-H/dMMR, Advanced Colorectal Cancer [Phase 1, Phase 2]
Recruiting a Phase 1/2 study of Cadonilimab, a PD-1/PD-L1 bispecific antibody, for PD-1/PD-L1 blockade-refractory, MSI-H/dMMR advanced color…
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CLINICAL_TRIALS research · 2025-03-19Clinical Trial Update: Tumor Deposits in Colorectal Cancer and Its Prognostic Value in Survival and Metastasis
A clinical trial conducted by Minia University is currently recruiting to evaluate whether tumor deposits in colorectal cancer have prognost…
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CLINICAL_TRIALS research · 2025-03-19Clinical Trial Update: Efficacy and Safety of Trifluridine/tipiracil (TAS-102) Combined with Bevacizumab and Putalimab in the Treatment of Patients with MCRC After Cytoreductive Surgery: a Single-arm, Single-center Clinical Study [Phase 1]
Phase 1, single-arm study evaluating trifluridine/tipiracil (TAS-102) in combination with bevacizumab and putalimab for metastatic colorecta…
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CLINICAL_TRIALS withdrawal · 2025-03-19Clinical Trial Update: A Post-marketing Surveillance to Assess the Safety and Effectiveness of Zirabev in Domestic Patients With Various Cancer
Pfizer's post-marketing surveillance study of Zirabev to assess safety and effectiveness in domestic cancer patients has been withdrawn.
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CLINICAL_TRIALS research · 2025-03-19Clinical Trial Update: Modulated Mid-frequency Whole-body Electromyostimulation and Nutritional Therapy in Gastrointestinal Cancer Patients [NA]
Clinical trial update from the University of Cologne describing a study of modulated mid-frequency whole-body electromyostimulation with nut…
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CLINICAL_TRIALS trial_result · 2025-03-18Clinical Trial Update: Safety and Activity of PolyPEPI1018 Plus Atezolizumab in Colorectal Cancer. [Phase 2]
Phase 2 trial evaluating safety and anti-tumor activity of PolyPEPI1018 plus atezolizumab in metastatic colorectal cancer.
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CLINICAL_TRIALS trial_result · 2025-03-18Clinical Trial Update: Safety and Efficacy of the Olympus CADe System in Real-time Colonoscopy
Completed clinical trial assessing safety and efficacy of the Olympus CADe System used during real-time colonoscopy for colorectal cancer de…
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CLINICAL_TRIALS trial_result · 2025-03-18Clinical Trial Update: Intestinal Flora Differences Between Colorectal Cancer Patients and Healthy Individuals
A completed clinical trial evaluating differences in intestinal flora between colorectal cancer patients and healthy controls.
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CLINICAL_TRIALS trial_result · 2025-03-18Clinical Trial Update: Hybrid-APC Margin Ablation to Prevent Post EMR Adenoma Recurrence [NA]
This clinical trial update reports results for Hybrid-APC Margin Ablation aimed at preventing recurrence of colon adenomas after endoscopic …
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CLINICAL_TRIALS research · 2025-03-18Clinical Trial Update: CapeOX Combined With Bevacizumab Plus Anti-PD1 Antibody as Neoadjuvant Therapy for Locally Recurrent Colorectal Cancer [Phase 2]
Phase 2 neoadjuvant trial evaluating CapeOX plus Bevacizumab and an anti-PD-1 antibody for locally recurrent colorectal cancer is currently …
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CLINICAL_TRIALS trial_result · 2025-03-18Clinical Trial Update: Colorectal Cancer Screening in Average-risk Population: Immunochemical Fecal Occult Blood Testing Versus Colonoscopy [NA]
This trial compared immunochemical fecal occult blood testing (FIT) to colonoscopy for colorectal cancer screening in average-risk adults. T…
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CLINICAL_TRIALS research · 2025-03-18Clinical Trial Update: Intrathecal Morphine Versus Epidural Analgesia for Laparoscopic Colon Surgery [Phase 4]
A Phase 4 trial is comparing intrathecal morphine with epidural analgesia for postoperative pain management after laparoscopic colon surgery…
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CLINICAL_TRIALS withdrawal · 2025-03-18Clinical Trial Update: TT-4 As a Single Agent in Subjects with Advanced Selected Solid Tumors [Phase 1, Phase 2]
Tarus Therapeutics has withdrawn its TT-4 single-agent trial in advanced solid tumors across Phase 1 and Phase 2. The listed conditions incl…
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CLINICAL_TRIALS research · 2025-03-18Clinical Trial Update: Study to Evaluate D-1553 in Subjects With Solid Tumors [Phase 1, Phase 2]
This clinical trial update shows an ongoing Phase 1/2 study of D-1553 in adults with solid tumors, including non-small cell lung cancer and …
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CLINICAL_TRIALS research · 2025-03-17Clinical Trial Update: MRD-Guided Surveillance in Resectable Stage IV Metastatic Colorectal Cancer (SURVEILLANCE-II)
A ClinicalTrials.gov entry describing SURVEILLANCE-II, a study using MRD-guided surveillance for patients with resectable stage IV metastati…
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CLINICAL_TRIALS research · 2025-03-17Clinical Trial Update: Prospective Data Collection Initiative on Colorectal Cancer
A prospective data collection initiative on colorectal cancer is being conducted by the Dutch Colorectal Cancer Group and is currently recru…
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CLINICAL_TRIALS research · 2025-03-17Clinical Trial Update: MRD-Guided Surveillance in Locally Advanced Mid-Low Rectal Cancer (SURVEILLANCE-III)
This clinical trial update discusses MRD-guided surveillance for locally advanced mid-low rectal cancer under the SURVEILLANCE-III study. Th…
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CLINICAL_TRIALS research · 2025-03-17Clinical Trial Update: MRD-Guided Surveillance in Operable Colon Adenocarcinoma (I-III)(SURVEILLANCE-I)
A clinical trial update on MRD-guided surveillance for operable colon adenocarcinoma (stages I–III), sponsored by Fudan University, with sta…
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CLINICAL_TRIALS research · 2025-03-17Clinical Trial Update: Adding Family History of Colorectal Cancer to the Dutch FIT-based Screening Program [NA]
The trial evaluating adding family history of colorectal cancer to the Dutch FIT-based screening program has completed.
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CLINICAL_TRIALS research · 2025-03-14Clinical Trial Update: CapeOX Combined With Bevacizumab Plus Anti-PD1 Antibody as Neoadjuvant Therapy for Microsatellite Stable Locally Advanced Rectal Cancer [Phase 2]
Phase 2 neoadjuvant trial evaluating CapeOX plus bevacizumab and an anti-PD1 antibody for microsatellite-stable locally advanced rectal/colo…