Colorectal Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-08-06Clinical Trial Update: Second-line Standard Treatment Sequential TAS-102 and Bevacizumab Combined With Local Treatment in Advanced Colorectal Cancer [Phase 2]
Phase 2 trial evaluating sequential TAS-102 and bevacizumab, in combination with local treatment, as second-line therapy for advanced/metast…
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CLINICAL_TRIALS research · 2025-08-06Clinical Trial Update: Microbiota: Its Role in Chronic Inflammation, IDB and Risk of Colorectal Cancer. Evaluation of a Predictive Prognostic Model With Therapeutic Implications
This entry notes an ongoing University of Messina clinical trial examining the role of the gut microbiota in chronic inflammation and colore…
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CLINICAL_TRIALS research · 2025-08-06Clinical Trial Update: Patient-reported Outcomes (PRO) and Treatment Outcomes of Chinese Patients With MSS-type Advanced Colorectal Cancer Who Received the Zidovudine Combination Regimen in the Real World
This report describes an ongoing trial evaluating patient-reported outcomes and treatment outcomes for Chinese patients with microsatellite-…
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CLINICAL_TRIALS research · 2025-08-05Clinical Trial Update: Risk Factor Assessment for the Development of Surgical Site Infection in Patients Undergoing Colorectal Cancer Surgery
A completed clinical trial evaluating risk factors for surgical site infection after colorectal cancer surgery.
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CLINICAL_TRIALS trial_result · 2025-08-05Clinical Trial Update: Messaging Intervention to Increase Medicare Annual Wellness Visits -- The NUDGE AWV Clinical Trial [NA]
The trial evaluated a messaging intervention to increase Medicare Annual Wellness Visits and cancer screenings (breast and colorectal) and i…
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CLINICAL_TRIALS research · 2025-08-05Clinical Trial Update: A Study of SYS6010 in Combination With SYH2051 in Patients With Advanced Colorectal Cancer and Other Gastrointestinal Tumors [NA]
Clinical trial update for SYS6010 in combination with SYH2051 in patients with advanced colorectal cancer and other gastrointestinal cancers…
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CLINICAL_TRIALS trial_result · 2025-08-05Clinical Trial Update: Patient Reminders Optimizing Mail-in Prevention Testing for Colorectal Cancer [NA]
Completed clinical trial evaluating patient reminders to optimize mail-in colorectal cancer screening uptake. The study, sponsored by Emily …
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CLINICAL_TRIALS research · 2025-08-03Clinical Trial Update: A Study of TRK-950 in Combinations With Anti-Cancer Treatment Regimens in Patients With Advanced Solid Tumors [Phase 1]
Phase 1 trial update for TRK-950 in combination with anti-cancer regimens in patients with advanced solid tumors; the study is active but no…
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CLINICAL_TRIALS research · 2025-08-03Clinical Trial Update: Cetuximab Plus FOLFOXIRI vs Cetuximab Plus FOLFOX For CRCLM [Phase 2]
Phase 2 clinical trial evaluating cetuximab plus FOLFOXIRI versus cetuximab plus FOLFOX for colorectal cancer with liver metastases; the stu…
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CLINICAL_TRIALS trial_result · 2025-08-03Clinical Trial Update: Phase 2 Study of DKN-01 in Colorectal Cancer [Phase 2]
Leap Therapeutics’ DKN-01 Phase 2 study in colorectal cancer has completed.
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CLINICAL_TRIALS research · 2025-08-01Clinical Trial Update: Low Stable Pressure Pneumoperitoneum in Colorectal Surgery (CROSS STUDY)
A trial update for the CROSS study investigating low stable pressure pneumoperitoneum in colorectal surgery is currently recruiting patients…
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CLINICAL_TRIALS research · 2025-08-01Clinical Trial Update: OligoCare TwiCs (Trials Within Cohorts) Trial Comparing Acute Toxicity in Single-fraction vs Multiple-fraction SBRT for Metastasis-directed Treatment (SPRINT) [NA]
This TWiCs trial compares acute toxicity of single-fraction versus multiple-fraction SBRT for metastasis-directed treatment across several c…
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CLINICAL_TRIALS research · 2025-08-01Clinical Trial Update: A Novel Oral Synbiotic Formula in Reducing Advanced Adenoma Recurrence and Colorectal Neoplasia-related Bacterial Gene Markers [NA]
A novel oral synbiotic formula is being studied in a recruiting clinical trial to reduce recurrence of advanced colorectal adenomas and to m…
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CLINICAL_TRIALS research · 2025-08-01Clinical Trial Update: Efficacy Study of Digoxin Combined With Serplulimab and Chemotherapy in First-Line Treatment of MSS Advanced Colorectal Cancer [Phase 1, Phase 2]
Clinical trial update on the efficacy study of digoxin combined with serplulimab and chemotherapy as first-line treatment for MSS advanced c…
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CLINICAL_TRIALS research · 2025-07-31Clinical Trial Update: CT-95 in Advanced Cancers Associated With Mesothelin Expression [Phase 1]
Phase 1 trial CT-95 for mesothelin-expressing tumors is currently recruiting across multiple indications, including epithelial ovarian cance…
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CLINICAL_TRIALS research · 2025-07-31Clinical Trial Update: Aspirin in Colorectal Cancer Liver Metastases [Phase 2, Phase 3]
An Oslo University Hospital-sponsored trial is evaluating aspirin for colorectal cancer with liver metastases. The study spans Phase 2 and P…
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CLINICAL_TRIALS research · 2025-07-31Clinical Trial Update: Safety and Effectiveness Study of Pre-operative Artesunate in Stage II/ III Colorectal Cancer [Phase 2]
Phase 2 study examining pre-operative artesunate for safety and effectiveness in stage II/III colorectal cancer; current status is NOT_YET_R…
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CLINICAL_TRIALS research · 2025-07-31Clinical Trial Update: Application of Polygenic Methylation Markers in Postoperative Recurrence Monitoring of Colorectal Cancer
A clinical trial by Singlera Genomics is evaluating polygenic methylation markers for monitoring postoperative recurrence in colorectal canc…
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CLINICAL_TRIALS research · 2025-07-31Clinical Trial Update: Simultaneous vs. Staged Resection of Colorectal Cancer With Synchronous Liver Metastases [NA]
A clinical trial evaluating simultaneous versus staged surgical resection of colorectal cancer with synchronous liver metastases, sponsored …
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CLINICAL_TRIALS trial_result · 2025-07-30Clinical Trial Update: Long-Term Follow-up Study of Subjects Treated With Autologous T Cells Using the Sleeping Beauty System to Express TCRs
Alaunos Therapeutics reports long-term follow-up data from subjects treated with autologous T cells engineered with a Sleeping Beauty system…
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CLINICAL_TRIALS withdrawal · 2025-07-30Clinical Trial Update: HLA Typing & Tumor Neoantigen Identification for Phase I/II Study of Autologous TCR-T Cells in Subjects With Solid Tumors
Alaunos Therapeutics reports termination of a Phase I/II autologous TCR-T cell trial across several solid tumors. The study focused on HLA t…
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CLINICAL_TRIALS research · 2025-07-30Clinical Trial Update: Fruquintinib With or Without HAI-FOLFOX for Refractory Colorectal Cancer [Phase 2, Phase 3]
Clinical trial update for a Phase 2/3 study evaluating Fruquintinib with or without hepatic artery infusion FOLFOX in patients with refracto…
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CLINICAL_TRIALS trial_result · 2025-07-30Clinical Trial Update: Prophylactic PIPAC in Patients With High-risk Colorectal Cancer [Phase 3]
Phase 3 trial evaluating prophylactic PIPAC in high-risk colorectal cancer patients; the study status is NOT_YET_RECRUITING.
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CLINICAL_TRIALS research · 2025-07-30Clinical Trial Update: Phase I Study of Autologous CD8+ and CD4+ Engineered T Cell Receptor T Cells in Subjects With Advanced or Metastatic Solid Tumor [Phase 1, Phase 2]
Update on a Phase I/II autologous engineered TCR T-cell therapy trial for advanced pancreatic ductal adenocarcinoma, non-small cell lung can…
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CLINICAL_TRIALS research · 2025-07-29Clinical Trial Update: Proposal of a Novel Model for Identifying Complete Response in dMMR Colon Cancer Following Neoadjuvant Immunotherapy
An update from a completed trial proposes a novel model to identify complete pathological response in dMMR colon cancer after neoadjuvant im…