Colorectal Cancer

• CLINICAL_TRIALS research · 2026-04-21
  Clinical Trial Update: Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer [Phase 3]

  Pfizer is sponsoring a Phase 3 clinical trial to evaluate PF-08634404 in combination with chemotherapy for adults with metastatic colorectal…

• CLINICAL_TRIALS research · 2026-04-21
  Clinical Trial Update: A Study to Learn More About How Safe BAY 3771249 is and How Well it Works in People With Advanced or Metastatic Colorectal Cancer That Has a KRAS G12D Mutation [Phase 1]

  Phase 1 research studying the safety and initial effectiveness of BAY 3771249 in people with advanced or metastatic colorectal cancer harbor…

• CLINICAL_TRIALS research · 2026-04-21
  Clinical Trial Update: Testing the Addition of Nivolumab to Standard Treatment for Patients With Metastatic or Unresectable Colorectal Cancer That Have a BRAF Mutation [Phase 2]

  A Phase 2 trial evaluating adding nivolumab to standard therapy for patients with metastatic or unresectable colorectal cancer with a BRAF m…

• CLINICAL_TRIALS research · 2026-04-21
  Clinical Trial Update: Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies [Phase 1, Phase 2]

  Phase 1/2 clinical trial of S241656 in RAS/MAPK mutation-positive malignancies is currently recruiting. The study targets non-small cell lun…

• CLINICAL_TRIALS research · 2026-04-21
  Clinical Trial Update: A Study to Investigate the Safety and Efficacy of KQB368 as Monotherapy in Participants With Advanced Solid Malignancies [Phase 1]

  Phase 1 study to assess safety and preliminary efficacy of KQB368 as monotherapy in participants with advanced solid malignancies; the trial…

• Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
• CLINICAL_TRIALS research · 2026-04-21
  Clinical Trial Update: The Impact of Image-Assisted Colonoscope on Patient Experience, Physician Workload, and Examination Quality [NA]

  This clinical trial investigates image-assisted colonoscopy and its effects on patient experience, physician workload, and examination quali…

• CLINICAL_TRIALS research · 2026-04-21
  Clinical Trial Update: Collection of Blood From Patients With Cancer

  Clinical trial update indicating ongoing recruitment to collect blood samples from patients with cancer for research purposes. The listed co…

• CLINICAL_TRIALS research · 2026-04-21
  Clinical Trial Update: Clinical Outcomes After Non-curative Endoscopic Resection in Early Colorectal Cancer: A Multicenter Study

  This entry describes a multicenter clinical trial evaluating outcomes after non-curative endoscopic resection in patients with early colorec…

• CLINICAL_TRIALS research · 2026-04-21
  Clinical Trial Update: Phase I Study of [177Lu]Lu-DFC413 in Patients With Solid Tumors [Phase 1]

  Phase I study update for the radiopharmaceutical [177Lu]Lu-DFC413 in patients with various solid tumors, currently recruiting.

• CLINICAL_TRIALS trial_result · 2026-04-20
  Clinical Trial Update: Efficacy and Safety Study of Tisotumab Vedotin for Patients With Solid Tumors [Phase 2]

  This Phase 2 trial update evaluates the efficacy and safety of tisotumab vedotin in solid tumors. It includes colorectal cancer, non-small c…

• CLINICAL_TRIALS research · 2026-04-20
  Clinical Trial Update: Neoadjuvant Serplulimab & Bevacizumab With FOLFOX vs. FOLFOX Alone in RAS/BRAF WT, pMMR/MSS CRC Patients [Phase 2, Phase 3]

  A neoadjuvant trial comparing serplulimab plus bevacizumab with FOLFOX versus FOLFOX alone in RAS/BRAF wild-type, pMMR/MSS colorectal cancer…

• CLINICAL_TRIALS research · 2026-04-20
  Clinical Trial Update: Regular Diet After Colorectal Surgery [NA]

  This clinical trial investigates whether a regular diet after colorectal surgery is safe and feasible. The study is not yet recruiting.

• CLINICAL_TRIALS research · 2026-04-20
  Clinical Trial Update: Testing the Effectiveness of the Anti-cancer Drug Pidnarulex (CX-5461), in Combination With Another Anti-cancer Drug Cemiplimab (REGN2810), in Treating Refractory Microsatellite Stable Colorectal Cancer [Phase 1, Phase 2]

  A Phase 1/2 clinical trial evaluating pidnarulex (CX-5461) in combination with cemiplimab (REGN2810) for refractory microsatellite-stable co…

• CLINICAL_TRIALS research · 2026-04-20
  Clinical Trial Update: A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People With Colorectal Cancer (MK-1084-012/KANDLELIT-012) [Phase 3]

  Phase 3 clinical trial evaluating Calderasib (MK-1084) in combination with targeted therapy and chemotherapy for colorectal cancer is curren…

• CLINICAL_TRIALS research · 2026-04-20
  Clinical Trial Update: A Study to Learn About the Study Medicine Called PF-08032562 in People With Advanced or Metastatic Solid Tumors [Phase 1]

  Phase 1 trial update evaluating PF-08032562 in people with advanced or metastatic solid tumors, including breast cancer and colorectal cance…

• CLINICAL_TRIALS research · 2026-04-20
  Clinical Trial Update: A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors [Phase 1]

  Phase 1 study evaluating SGN-CEACAM5C in adults with advanced solid tumors is currently recruiting.

• CLINICAL_TRIALS research · 2026-04-20
  Clinical Trial Update: A Study to Learn About the Study Medicine PF-07934040 When Given Alone or With Other Anti-cancer Therapies in People With Advanced Solid Tumors That Have a Genetic Mutation. [Phase 1]

  Pfizer is conducting a Phase 1 study of PF-07934040 in adults with advanced solid tumors carrying a genetic mutation, evaluating the drug al…

• CLINICAL_TRIALS research · 2026-04-20
  Clinical Trial Update: Evaluating the Effects of an Exercise Intervention on the Gut Microbiota in Stage II-III Colorectal Cancer Survivors [NA]

  A clinical trial from Fred Hutchinson Cancer Center is evaluating the effects of an exercise intervention on gut microbiota in survivors of …

• CLINICAL_TRIALS research · 2026-04-20
  Clinical Trial Update: A Study of Novel Study Interventions and Combinations in Participants With Colorectal Cancer [Phase 2]

  AstraZeneca is conducting a Phase 2 trial evaluating novel interventions and combinations for metastatic colorectal cancer, currently recrui…

• CLINICAL_TRIALS research · 2026-04-20
  Clinical Trial Update: MOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors [Phase 1]

  Phase 1 trial MOONRAY-01 evaluating LY3962673 in KRAS G12D-mutant solid tumors is currently recruiting. The study appears to include pancrea…

• CLINICAL_TRIALS research · 2026-04-20
  Clinical Trial Update: A Study to Investigate the Safety, Pharmacokinetics, and Preliminary Efficacy of IDE574 Therapy in Adult Participants With Advanced Solid Tumors [Phase 1, Phase 2]

  IDEAYA Biosciences is conducting a Phase 1/2 study to evaluate the safety, pharmacokinetics, and preliminary efficacy of IDE574 in adults wi…

• CLINICAL_TRIALS trial_result · 2026-04-17
  Clinical Trial Update: A Phase 1 Clinical Trial of AUR106 in Patients With Relapsed Advanced Malignancies [Phase 1]

  Phase 1 trial of AUR106 in relapsed advanced malignancies has been terminated; the document provides a status update on this study.

• CLINICAL_TRIALS research · 2026-04-17
  Clinical Trial Update: SBRT Followed by PD-1 Inhibitor, Bevacizumab and TAS-102 as Third-Line Therapy for Recurrent/Metastatic Colorectal Cancer [Phase 2]

  This Phase 2 clinical trial evaluates a third-line treatment for recurrent/metastatic colorectal cancer using SBRT followed by a PD-1 inhibi…

• CLINICAL_TRIALS trial_result · 2026-04-17
  Clinical Trial Update: A Study of CTX-009 in Adult Patients With Metastatic Colorectal Cancer [Phase 2]

  A Phase 2 study evaluating CTX-009 in adults with metastatic colorectal cancer has completed, according to the trial record.

• CLINICAL_TRIALS trial_result · 2026-04-17
  Clinical Trial Update: Zanidatamab Before Surgery for the Treatment of HER2 Positive Colon and Rectal Cancer in Patients Planned for Curative Intent Treatment [Phase 2]

  Phase 2 clinical trial evaluating zanidatamab given before surgery for HER2-positive colon and rectal cancer planned for curative-intent tre…