Colorectal Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-12-03Clinical Trial Update: An Investigational Immuno-therapy Study Of Nivolumab In Combination With Trametinib With Or Without Ipilimumab In Participants With Previously Treated Cancer of the Colon or Rectum That Has Spread [Phase 1, Phase 2]
A Phase 1/2 trial of combination therapy with nivolumab and trametinib, with or without ipilimumab, in previously treated colorectal cancer;…
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: Trifluridine/Tipiracil Plus Fruquintinib vs. Trifluridine/Tipiracil Plus Bevacizumab in Refractory Metastatic Colorectal Cancer: A Randomized, Controlled, Open-Label, Non-Inferiority Trial [Phase 2]
A Phase 2 randomized, open-label, non-inferiority trial comparing trifluridine/tipiracil plus fruquintinib versus trifluridine/tipiracil plu…
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: Study of GV20-0251 in Participants With Solid Tumor Malignancies [Phase 1, Phase 2]
GV20 Therapeutics is evaluating GV20-0251 in a Phase 1/2 trial for adults with various solid tumors, and the study is currently recruiting. …
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CLINICAL_TRIALS trial_result · 2025-12-03Clinical Trial Update: A Phase I Clinical Study of Recombinant Humanized Anti-BTLA Monoclonal Antibody (JS004) Injection Combined With Toripalimab Injection in Patients With Advanced Solid Tumors [Phase 1]
A Phase I trial of JS004, a recombinant humanized anti-BTLA monoclonal antibody, in combination with toripalimab for advanced solid tumors h…
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: Colorectal Cancer Awareness, Research and Education and Screening - Rural Expansion, Access and Capacity for Health
A clinical trial update for a study on colorectal cancer awareness, education, and screening with rural expansion and access initiatives; th…
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: Pooled Mutant KRAS-Targeted Long Peptide Vaccine Combined With Nivolumab and Ipilimumab for Patients With Resected Mismatch Repair Protein (MMR-p) Colorectal and Pancreatic Cancer [Phase 1]
Phase 1 trial update of a pooled mutant KRAS-targeted long peptide vaccine combined with nivolumab and ipilimumab in patients with resected …
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CLINICAL_TRIALS trial_result · 2025-12-03Clinical Trial Update: A Study of Enhancing Response to MK-3475 in Advanced Colorectal Cancer [Phase 1]
A Phase 1 study of pembrolizumab (MK-3475) for advanced colorectal cancer has completed.
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: Plasma 5hmC Signatures as a Marker of Colorectal / Appendiceal Peritoneal Metastasis
This clinical trial update reports on a study evaluating plasma 5hmC DNA signatures as biomarkers for metastasis in colorectal and appendice…
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: Holistic Acupuncture for Patients With Chemotherapy Induced Nausea [NA]
A clinical trial update for a holistic acupuncture intervention to treat chemotherapy-induced nausea, sponsored by Vejle Hospital, currently…
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: DETERMINE Trial Treatment Arm 04: Trastuzumab in Combination With Pertuzumab in Adult, Paediatric and Teenage/Young Adult Patients With Cancers With HER2 Amplification or Activating Mutations [Phase 2, Phase 3]
The DETERMINE trial update investigates the combination of Trastuzumab and Pertuzumab for HER2-amplified or activating-mutant cancers in adu…
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: A Study of GFH375 Combined With Cetuximab or Chemotherapy in Participants With Solid Tumors Harboring KRAS G12D Mutation [Phase 1, Phase 2]
This is a Phase 1/2 clinical trial update evaluating GFH375 in combination with cetuximab or chemotherapy for KRAS G12D-mutant solid tumors,…
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: Exploration of the Relationship Between Mismatch Repair Status of Colorectal Cancer and Lymph Node Metastasis Patterns and Pathological High-risk Factors
This completed clinical trial investigates how mismatch repair status in colorectal cancer relates to lymph node metastasis patterns and pat…
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: The Safety and Efficacy of Cetuximab Beta Plus Fruquintinib With or Without Immune Checkpoint Inhibitorrs in First-line Treatment of RAS/BRAF Wild Type Unresectable Metastatic Colorectal Cancer [Phase 2]
Phase 2 trial evaluating cetuximab beta plus fruquintinib with or without immune checkpoint inhibitors as first-line therapy for RAS/BRAF wi…
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: REVOLUTION Surgery (REVOLUTION Surgery)
The REVOLUTION Surgery trial, led by the University of Edinburgh, is currently recruiting and studying cachexia alongside multiple cancers i…
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: Proactive Outreach With FIT [NA]
A clinical trial update for NYU Langone Health examining proactive outreach using fecal immunochemical testing (FIT) for colorectal cancer s…
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: Social Health, Activity Behaviors, and Quality of Life Among Young Adult Cancer Survivors
This ClinicalTrials.gov entry describes a recruiting USC-led study evaluating social health, activity behaviors, and quality of life among y…
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: Immune Cell Therapy for Advanced Solid Tumors [Phase 1, Phase 2]
This is a Phase 1/2 clinical trial update for an immune cell therapy targeting advanced solid tumors, including locally advanced or metastat…
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CLINICAL_TRIALS trial_result · 2025-12-01Clinical Trial Update: Interest of the Nefopam and PCA Morphine Combination for Postoperative Analgesia in Patients Undergoing Colon Surgery [NA]
This clinical trial update notes a completed study evaluating the combination of nefopam and PCA morphine for postoperative analgesia in pat…
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CLINICAL_TRIALS trial_result · 2025-11-28Clinical Trial Update: A Community-Based Educational Intervention to Improve Colorectal Cancer Screening
The community-based educational intervention trial aimed at improving colorectal cancer screening has been suspended.
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CLINICAL_TRIALS research · 2025-11-28Clinical Trial Update: Using 4D Urinary Proteomics to Predict and Evaluate Treatment Response in Colorectal Cancer
This ClinicalTrials.gov update describes a study using 4D urinary proteomics to predict and evaluate treatment response in colorectal cancer…
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CLINICAL_TRIALS research · 2025-11-28Clinical Trial Update: A Study of Tumor-Agnostic MRD Detection in Stage III Colorectal Cancer
This clinical trial update describes a tumor-agnostic MRD (minimal residual disease) detection study in stage III colorectal cancer, using c…
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CLINICAL_TRIALS research · 2025-11-26Clinical Trial Update: A Noninvasive and Screening miRNA Signature for Gastrointestinal Cancer
This clinical trial update describes a noninvasive miRNA-based test being explored for screening gastrointestinal cancers. It is currently r…
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CLINICAL_TRIALS trial_result · 2025-11-25Clinical Trial Update: QUILT-3.038: Active Immunotherapy CEA Vaccine in Patients With Malignancies Expressing CEA [Phase 1, Phase 2]
The document provides a clinical trial update on QUILT-3.038, a Phase 1/2 active immunotherapy vaccine targeting carcinoembryonic antigen (C…
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CLINICAL_TRIALS research · 2025-11-25Clinical Trial Update: Clinical Trial of TB511 in Advanced Solid Tumors [Phase 1, Phase 2]
This update covers an early-phase trial of TB511 in advanced solid tumors, including non-small cell lung cancer and prostate cancer, with co…
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CLINICAL_TRIALS research · 2025-11-25Clinical Trial Update: Perioperative Complications After Neoadjuvant Radiotherapy for Colorectal Cancer
This clinical trial update discusses perioperative complications after neoadjuvant radiotherapy for colorectal cancer. The study is currentl…