Colorectal Cancer

• CLINICAL_TRIALS research · 2025-12-30
  Clinical Trial Update: Collection of Samples From the United States Population for Optimization and Evaluation of Colorectal Cancer (CRC) Plasma Circulating Free-DNA (cfDNA) Marker Panel Performance

  This clinical trial is recruiting in the United States to collect samples to optimize and evaluate a plasma circulating free DNA (cfDNA) mar…

• CLINICAL_TRIALS trial_result · 2025-12-29
  Clinical Trial Update: A First-in-Human, Phase 1 Study of JAB-3312 in Adult Patients With Advanced Solid Tumors [Phase 1]

  First-in-human Phase 1 study of JAB-3312 in adults with advanced solid tumors has been completed, evaluating multiple tumor indications.

• CLINICAL_TRIALS research · 2025-12-29
  Clinical Trial Update: PET-imaging of Two Vartumabs in Patients With Solid Tumors [EARLY_Phase 1]

  This early-phase PET-imaging trial evaluates two vartumabs in patients with solid tumors and is currently recruiting.

• CLINICAL_TRIALS trial_result · 2025-12-29
  Clinical Trial Update: Postbiotics for Mitigation of Postoperative Dysbiosis in Gastrointestinal Cancer Surgery [NA]

  A clinical trial update describing a study of postbiotics to mitigate postoperative dysbiosis in gastrointestinal cancer surgery, with enrol…

• CLINICAL_TRIALS research · 2025-12-26
  Clinical Trial Update: Observational Basket Trial to Collect Tissue to Develop and Train a Live Tumor Diagnostic Platform

  An observational basket trial sponsored by Elephas aims to collect tissue to develop and train a live tumor diagnostic platform across multi…

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• CLINICAL_TRIALS trial_result · 2025-12-26
  Clinical Trial Update: Prognostic Value of Tissue Factor (TF) in Blood t in Colorectal Cancer in Adults [EARLY_Phase 1]

  A completed EARLY Phase 1 trial evaluating the prognostic value of Tissue Factor in the blood of adults with colorectal cancer.

• CLINICAL_TRIALS trial_result · 2025-12-26
  Clinical Trial Update: Community Collaboration to Advance Racial/Ethnic Equity in CRC Screening [NA]

  This clinical trial update reports the completion of a community-collaboration study to advance racial/ethnic equity in colorectal cancer sc…

• CLINICAL_TRIALS research · 2025-12-26
  Clinical Trial Update: Blood Screening for Adult Colorectal Cancer

  A clinical trial sponsored by University Hospital, Lille is currently recruiting to evaluate a blood-based screening method for colorectal c…

• CLINICAL_TRIALS research · 2025-12-24
  Clinical Trial Update: mFOLFOX6 + Bevacizumab + PD-1 Monoclonal Antibody Vs. mFOLFOX6 in Locally Advanced pMMR/MSS CRC [Phase 3]

  A Phase 3 randomized trial compares mFOLFOX6 plus bevacizumab with a PD-1 monoclonal antibody versus standard mFOLFOX6 in locally advanced p…

• CLINICAL_TRIALS trial_result · 2025-12-24
  Clinical Trial Update: Risk of Metachronous Advanced Colorectal Neoplastic Among Individuals With Varying Numbers of Non-Advanced Adenomas Detected During Screening Colonoscopy

  This completed clinical trial investigated the risk of metachronous advanced colorectal neoplasia among individuals with varying numbers of …

• CLINICAL_TRIALS withdrawal · 2025-12-24
  Clinical Trial Update: A Study of Select Drug Combinations in Adult Patients With Advanced/Metastatic BRAF V600 Colorectal Cancer [Phase 1]

  A Phase 1 study evaluating select drug combinations in adult patients with advanced/metastatic BRAF V600 colorectal cancer has been terminat…

• CLINICAL_TRIALS research · 2025-12-24
  Clinical Trial Update: The Ohio State University (OSU) SCREEN Community Program [NA]

  A recruiting clinical trial at Ohio State University's Comprehensive Cancer Center under the SCREEN Community Program, enrolling participant…

• CLINICAL_TRIALS research · 2025-12-24
  Clinical Trial Update: Comparing 68Ga-FAPI PET-Guided Abdominal Radiotherapy Combined With Second-Line Standard Therapy and Cadonilimab Versus Second-Line Standard Therapy in Colorectal Cancer With Peritoneal Metastasis [Phase 2]

  This Phase 2 trial is evaluating cadonilimab plus 68Ga-FAPI PET-guided abdominal radiotherapy versus second-line standard therapy in colorec…

• CLINICAL_TRIALS research · 2025-12-24
  Clinical Trial Update: Futibatinib in Combination With (Chemo)Immunotherapy in Colorectal Cancer and Other Solid Tumor Entities [Phase 2]

  Phase 2 clinical trial evaluating futibatinib in combination with chemotherapy and immunotherapy for colorectal cancer; trial is currently r…

• CLINICAL_TRIALS withdrawal · 2025-12-24
  Clinical Trial Update: STIL101 for Injection for the Treatment of Locally Advanced, Metastatic or Unresectable Pancreatic Cancer, Colorectal Cancer, Renal Cell Cancer, Cervical Cancer and Melanoma [Phase 1]

  A Phase 1 study of STIL101 for injection across pancreatic ductal adenocarcinoma, colorectal cancer, renal cell carcinoma, cervical cancer, …

• CLINICAL_TRIALS trial_result · 2025-12-23
  Clinical Trial Update: Evaluation of RBS2418 in Patients With Advanced, Metastatic, and Progressive Colorectal Cancer [Phase 2]

  Phase 2 clinical trial evaluating RBS2418 in patients with advanced, metastatic colorectal cancer; the study is currently recruiting.

• CLINICAL_TRIALS research · 2025-12-23
  Clinical Trial Update: Acupuncture for the Management of Postoperative Pain in Patients With Pancreatic or Colorectal Cancer Undergoing Surgery [NA]

  An update on a clinical trial evaluating acupuncture to manage postoperative pain in patients with pancreatic or colorectal cancer undergoin…

• CLINICAL_TRIALS research · 2025-12-23
  Clinical Trial Update: A Study of PT0511 in Participants With KRAS Mutated or Amplified Advanced Solid Tumors [Phase 1]

  A Phase 1 study evaluating PT0511 in adults with KRAS-mutated or amplified advanced solid tumors, including colorectal cancer, pancreatic ca…

• CLINICAL_TRIALS research · 2025-12-23
  Clinical Trial Update: Fecal Microbiota Transplant and Re-introduction of Anti-PD-1 Therapy (Pembrolizumab or Nivolumab) for the Treatment of Metastatic Colorectal Cancer in Anti-PD-1 Non-responders [Phase 2]

  Phase 2 trial investigating fecal microbiota transplant followed by re-introduction of anti-PD-1 therapy (pembrolizumab or nivolumab) for an…

• CLINICAL_TRIALS research · 2025-12-23
  Clinical Trial Update: LY3214996 and Cetuximab Alone or in Combination With Abemaciclib for the Treatment of Unresectable or Metastatic Colorectal Cancer [Phase 1, Phase 2]

  This clinical trial update covers a Phase 1/2 study evaluating LY3214996 with cetuximab, alone or in combination with abemaciclib, for unres…

• CLINICAL_TRIALS research · 2025-12-23
  Clinical Trial Update: Effect of Video Training on Patients' Self-Efficacy After Colorectal Surgery [NA]

  Clinical trial investigating the effect of video training on patients' self-efficacy after colorectal surgery; status is not yet recruiting.

• CLINICAL_TRIALS research · 2025-12-22
  Clinical Trial Update: The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas [Phase 2]

  A Phase 2 clinical trial update describes a program for in-home cancer treatment with remote expert support, currently recruiting for patien…

• CLINICAL_TRIALS research · 2025-12-22
  Clinical Trial Update: First-in-human Trial of STC-1010, an Immunotherapy, in Patients With Unresectable Locally Advanced or Metastatic Colorectal Cancer [Phase 1, Phase 2]

  First-in-human Phase 1/2 trial update of STC-1010 immunotherapy for unresectable locally advanced or metastatic colorectal cancer, sponsored…

• CLINICAL_TRIALS research · 2025-12-22
  Clinical Trial Update: Medical and Psychosocial Issues in Adolescents and Young Adults With Colorectal Cancer [NA]

  Clinical trial update on medical and psychosocial issues in adolescents and young adults with colorectal cancer; the study is active but not…

• CLINICAL_TRIALS research · 2025-12-22
  Clinical Trial Update: ColoReg: A Register for Gastrointestinal Endoscopy Reports and Examination Videos

  This entry describes the ColoReg trial, a register for gastrointestinal endoscopy reports and examination videos. The study is currently rec…