Colorectal Cancer
📧 Sign up to get email alerts when something new happens for Colorectal Cancer.
Sign up freeTop drugs studied for this disease
-
FDA approval · 2008-06-23FDA Approved: VECTIBIX — Supplemental Application (Amgen, Inc)
The FDA approved Amgen's supplemental application for VECTIBIX (panitumumab), indicating regulatory approval for an updated indication or la…
-
CLINICAL_TRIALS trial_result · 2008-06-17Clinical Trial Update: Detection of Colorectal Cancer in Peripheral Blood by Septin 9 DNA Methylation Assay
A completed clinical trial evaluating the detection of colorectal cancer in peripheral blood using the Septin 9 DNA methylation assay.
-
CLINICAL_TRIALS research · 2008-06-09Clinical Trial Update: Improving Outcomes for Patients Requiring Oral Bowel Preparation for Colonoscopy [NA]
A clinical trial update exploring ways to improve bowel preparation outcomes for colonoscopy; no results or current status are provided.
-
CLINICAL_TRIALS trial_result · 2008-05-29Clinical Trial Update: Phase I Study of MEDI522 in Patients With Irinotecan-Refractory Advanced Colorectal Cancer [Phase 1, Phase 2]
This Clinical Trial Update reports completion of a Phase I/II study of MEDI522 in irinotecan-refractory advanced colorectal cancer.
-
CLINICAL_TRIALS trial_result · 2008-05-12Clinical Trial Update: A Follow-up Colonoscopy Examination in Patients Who Had Previously Undergone Screening Colonoscopy
This clinical trial update reports a follow-up colonoscopy examination in patients who had previously undergone screening colonoscopy. The s…
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS research · 2008-04-23Clinical Trial Update: Implementation of a New Strategy to Identify HNPCC Patients [NA]
The update describes implementing a new strategy to identify patients with hereditary nonpolyposis colorectal cancer (Lynch syndrome) for a …
-
CLINICAL_TRIALS trial_result · 2008-04-16Clinical Trial Update: Comparison of 2L NRL994 With NaP Preparation in Colon Cleansing Prior to Colonoscopies for Colon Tumor Screening [Phase 3]
Phase 3 trial comparing 2L NRL994 with sodium phosphate (NaP) bowel cleansing preparation for colonoscopy has completed.
-
CLINICAL_TRIALS trial_result · 2008-04-09Clinical Trial Update: An Open Label Study of a Peptide Vaccine in Patients With Stage III Colon Cancer [Phase 1]
An open-label Phase 1 trial evaluated a peptide vaccine in patients with stage III colorectal cancer (colon cancer); the study status is com…
-
CLINICAL_TRIALS research · 2008-03-19Clinical Trial Update: Circulating Tumor Cells in Patients With Metastatic Colorectal Cancer
An update on a clinical trial studying circulating tumor cells in patients with metastatic colorectal cancer.
-
CLINICAL_TRIALS research · 2008-03-06Clinical Trial Update: Phase 3 Study of Surgery Combined With Neoadjuvant Chemotherapy(XELOX) in Colorectal Cancer With Resectable Liver Metastasis [Phase 3]
Phase 3 trial evaluating surgery with neoadjuvant XELOX chemotherapy for colorectal cancer with resectable liver metastases; current study s…
-
CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: A Phase II Clinical Trial of Suppression of Human Antimouse Antibody and Human Antitoxin Response to Immunotoxin LMB-1 by Rituximab [Phase 2]
Phase II clinical trial evaluating Rituximab to suppress anti-mouse antibody and anti-toxin responses to the immunotoxin LMB-1 in several ca…
-
CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: A Phase II Study of 5-Fluorouracil Administered as a One Hour Infusion in Combination With Calcium Leucovorin and Interferon Alpha-2A in Advanced Colorectal Cancer [Phase 2]
A Phase II study evaluating 5-fluorouracil given as a one-hour infusion in combination with calcium leucovorin and interferon alfa-2a in adv…
-
CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: Phase II Study of the Role of Anti-CEA Antibody Immunoscintigraphy & Positron Emission Tomography in the Localization of Recurrent Colorectal Carcinoma in Patients With Rising Serum CEA Levels in the Absence of Imageable Disease by Conventional Modalities [Phase 2]
Phase II clinical trial evaluating anti-CEA antibody immunoscintigraphy combined with PET to localize recurrent colorectal cancer in patient…
-
CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: Phase I-II Multiple-Dose Safety and Efficacy Study of a Selective Inhibitor of Cyclooxygenase - 2 (SC-58635) in Hereditary Non-Polyposis Colorectal Cancer (HNPCC) Patients and Carriers [Phase 1]
This report covers Phase I-II multi-dose safety and efficacy data for a selective COX-2 inhibitor, SC-58635, in patients with hereditary non…
-
FDA approval · 2008-02-27FDA Approved: IRINOTECAN HYDROCHLORIDE — Original Application (Hospira, Inc.)
FDA approved Hospira, Inc.'s irinotecan hydrochloride under an original generic application, authorizing its use as a generic anticancer age…
-
FDA approval · 2008-02-27FDA Approved: IRINOTECAN HYDROCHLORIDE — Original Application (Fresenius Kabi USA, LLC)
FDA approved a generic irinotecan hydrochloride product under ANDA 077776 from Fresenius Kabi USA, LLC.
-
CLINICAL_TRIALS trial_result · 2008-02-21Clinical Trial Update: Is Barium Enema an Adequate Diagnostic Test for Patients With Positive FOBT? [NA]
This document provides an update on a completed clinical trial investigating whether a barium enema is an adequate diagnostic test for patie…
-
CLINICAL_TRIALS trial_result · 2008-01-08Clinical Trial Update: Alternative to Two-Stage Hepatectomy
A completed clinical trial from the University of Milan evaluating an alternative to the two-stage hepatectomy for patients with colorectal …
-
CLINICAL_TRIALS trial_result · 2007-12-28Clinical Trial Update: High Dose Simplified Folfiri in Advanced Colorectal Cancer: a Multicentre Phase II Study [Phase 2]
Phase II multicenter study evaluating a high-dose simplified FOLFIRI regimen in patients with advanced colorectal cancer; the update reports…
-
CLINICAL_TRIALS trial_result · 2007-12-21Clinical Trial Update: Capecitabine and Thalidomide in Previously Treated Metastatic Colorectal Carcinoma [Phase 2]
Completed Phase 2 trial evaluating the combination of capecitabine and thalidomide in previously treated metastatic colorectal cancer.
-
CLINICAL_TRIALS trial_result · 2007-12-21Clinical Trial Update: Study of Bevacizumab, Erlotinib, FOLFOX for Patients With Untreated Metastatic Colorectal Cancer [Phase 2]
Phase 2 study evaluating bevacizumab, erlotinib, and FOLFOX in patients with untreated metastatic colorectal cancer has completed.
-
CLINICAL_TRIALS trial_result · 2007-12-18Clinical Trial Update: A Phase 2 Study of Tomudex & Iressa as Second Line Chemotherapy in Subjects With Colorectal Carcinoma [Phase 2, Phase 3]
A phase 2/3 clinical trial evaluating Tomudex (raltitrexed) in combination with Iressa (gefitinib) as second-line chemotherapy for colorecta…
-
CLINICAL_TRIALS trial_result · 2007-11-29Clinical Trial Update: A Study of ABT-751 in Patients With Colorectal Cancer [Phase 2]
This document reports the completion of a Phase 2 clinical trial of ABT-751 in patients with colorectal cancer.
-
CLINICAL_TRIALS trial_result · 2007-11-27Clinical Trial Update: Clinical Trial in Patients With Metastatic Colorectal Cancer [Phase 2]
A Phase 2 clinical trial in patients with metastatic colorectal cancer has completed.
-
CLINICAL_TRIALS research · 2007-11-19Clinical Trial Update: Phase III Randomized Study of 5-FU, CoFactor, and Avastin vs. 5-FU, LV and Avastin for First-Line Colorectal Cancer. [Phase 3]
A Phase III randomized trial is evaluating 5-FU with CoFactor plus Avastin versus 5-FU with leucovorin plus Avastin as first-line therapy fo…