Colorectal Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2013-11-25Clinical Trial Update: Neoadjuvant Chemoradiotherapy and Adjuvant Chemotherapy in Treating Patients Who Are Undergoing Surgical Resection for Locally Advanced Rectal Cancer [Phase 2]
Phase 2 trial evaluating neoadjuvant chemoradiotherapy followed by adjuvant chemotherapy for locally advanced rectal cancer undergoing surgi…
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CLINICAL_TRIALS trial_result · 2013-11-25Clinical Trial Update: T Regulatory Lymphocytes (Treg) Depletion for Cancer Treatment Efficacy and Safety Study [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating depletion of regulatory T cells for cancer treatment efficacy and safety in colorectal cancer has comp…
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CLINICAL_TRIALS trial_result · 2013-11-21Clinical Trial Update: A Study of BIBW 2992 (Afatinib) in Patients With Metastatic Colorectal Cancer [Phase 2]
A Phase 2 study of afatinib (BIBW 2992) in metastatic colorectal cancer has completed and results have been posted.
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FDA approval · 2013-11-15FDA Approved: OXALIPLATIN — Supplemental Application (Winthrop U.S, a business of sanofi-aventis U.S. LLC)
FDA approved a supplemental application for Oxaliplatin submitted by Winthrop U.S., a business of Sanofi-Aventis U.S. LLC.
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CLINICAL_TRIALS trial_result · 2013-11-15Clinical Trial Update: Effect of Folate on Colon and Blood Cells [Phase 1]
A Phase 1 clinical trial evaluating the effect of folate on colon tissue and blood cells in individuals with pre-cancerous colorectal polyps…
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CLINICAL_TRIALS trial_result · 2013-11-13Clinical Trial Update: Analysis of Circulating Tumor DNA to Monitor Metastatic Colorectal Cancer Treatment
An update on a clinical trial evaluating whether circulating tumor DNA can monitor treatment response in metastatic colorectal cancer, compa…
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CLINICAL_TRIALS trial_result · 2013-11-07Clinical Trial Update: General Anesthesia Combined With Epidural Anesthesia Mitigates the Surgical Stress-related Immunosuppression in Patients With Colorectal Cancer [NA]
This completed trial suggests that using general anesthesia combined with epidural anesthesia may mitigate surgical stress-related immunosup…
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CLINICAL_TRIALS trial_result · 2013-11-06Clinical Trial Update: Oxaliplatin and Bevacizumab (Avastin™) With Either Fluorouracil and Leucovorin or Capecitabine in Treating Patients With Advanced Colorectal Cancer [Phase 3]
Phase 3 trial evaluated oxaliplatin and bevacizumab with either fluorouracil plus leucovorin or capecitabine in patients with advanced color…
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CLINICAL_TRIALS trial_result · 2013-11-06Clinical Trial Update: High-Dose Fluorouracil With or Without Leucovorin Compared With Standard Fluorouracil Plus Leucovorin Following Surgery in Treating Patients With Stage III Colon Cancer [Phase 3]
This Phase 3 trial evaluated high-dose fluorouracil with or without leucovorin versus standard fluorouracil plus leucovorin as adjuvant ther…
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CLINICAL_TRIALS trial_result · 2013-11-04Clinical Trial Update: First-Line FOLFOX-Bevacizumab for Advanced Colorectal Cancer With Wild-Type Ras [Phase 2]
Phase 2 trial update evaluating first-line FOLFOX-bevacizumab in advanced colorectal cancer with wild-type Ras; study terminated with result…
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CLINICAL_TRIALS trial_result · 2013-11-01Clinical Trial Update: Azacitidine and Entinostat in Treating Patients With Metastatic Colorectal Cancer [Phase 2]
Phase 2 trial evaluating azacitidine plus entinostat in patients with metastatic colorectal cancer has completed and results were posted in …
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CLINICAL_TRIALS trial_result · 2013-10-31Clinical Trial Update: Lapatinib and Cetuximab in Patients With Solid Tumors [Phase 1]
A Phase 1 clinical trial update reports completion of a study evaluating lapatinib and cetuximab in patients with solid tumors, including co…
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CLINICAL_TRIALS trial_result · 2013-10-29Clinical Trial Update: Studying a Quality of Life Questionnaire in Patients With Colorectal Cancer
A completed clinical trial assessing a quality-of-life questionnaire in patients with colorectal cancer.
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FDA approval · 2013-10-25FDA Approved: ZALTRAP — Supplemental Application (sanofi-aventis U.S. LLC)
The FDA approved a supplemental application for Zaltrap (ziv-aflibercept) from Sanofi-Aventis U.S. LLC, adding/expanding its marketed indica…
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CLINICAL_TRIALS trial_result · 2013-10-25Clinical Trial Update: EMD 273066 in Patients With Recurrent EpCAM Positive Ovarian, Prostate, Colorectal or Non-small Cell Lung Cancers When First Given Cyclophosphamide [Phase 1]
Phase 1 trial evaluating EMD 273066 in EpCAM-positive recurrent ovarian, prostate, colorectal, or non-small cell lung cancer when first trea…
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CLINICAL_TRIALS trial_result · 2013-10-25Clinical Trial Update: Fast Track Laparoscopic Surgery: A Better Option for Treating Colorectal Cancer Than Conventional Laparoscopic Surgery [NA]
Completed clinical trial comparing fast-track laparoscopic surgery to conventional laparoscopic surgery for colorectal cancer; results sugge…
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CLINICAL_TRIALS trial_result · 2013-10-23Clinical Trial Update: An Open Dose-finding Study of Oral Applied Hexaminolevulinate (HAL) Imaging in Patients With Suspicion or High Risk of Neoplasia in the Colon [Phase 1, Phase 2]
Terminated Phase 1/2 open-dose study evaluating oral hexaminolevulinate imaging in patients with suspected or high-risk colorectal neoplasia…
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CLINICAL_TRIALS trial_result · 2013-10-23Clinical Trial Update: Faith Moves Mountains: A Community Based Participatory Research (CBPR) Appalachian Wellness & Cancer Prevention Program [NA]
A community-based participatory research cancer prevention program in Appalachia focused on wellness and cancer prevention across multiple c…
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CLINICAL_TRIALS trial_result · 2013-10-22Clinical Trial Update: Study of FOLFIRI Plus Cetuximab Plus IMO-2055 in Patients With Colorectal Cancer [Phase 1]
Phase 1 study of FOLFIRI plus cetuximab and IMO-2055 in colorectal cancer has been terminated.
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CLINICAL_TRIALS trial_result · 2013-10-21Clinical Trial Update: Impact of Positron Emission Tomography Imaging Prior to Liver Resection for Colorectal Adenocarcinoma Metastases [Phase 3]
A Phase 3 trial assessed the impact of PET imaging prior to liver resection in colorectal cancer with liver metastases; the study has comple…
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CLINICAL_TRIALS trial_result · 2013-10-21Clinical Trial Update: OSI-906 and Irinotecan in Patients With Advanced Cancer [Phase 1]
Phase 1 trial of OSI-906 in combination with irinotecan in advanced colorectal cancer has been terminated.
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CLINICAL_TRIALS trial_result · 2013-10-16Clinical Trial Update: GM-CSF and Combination Chemotherapy in Treating Patients Who Are Undergoing Surgery for Stage II or Stage III Colon Cancer [Phase 2]
This is an update on a phase 2 trial evaluating GM-CSF with chemotherapy in patients undergoing surgery for stage II/III colon cancer.
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CLINICAL_TRIALS trial_result · 2013-10-01Clinical Trial Update: A Bioequivalence Study of Capecitabine Tablets [Phase 1]
Phase 1 bioequivalence study of Capecitabine tablets completed by Chia Tai Tianqing Pharmaceutical Group Co., Ltd. The study examined a Cape…
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CLINICAL_TRIALS trial_result · 2013-09-30Clinical Trial Update: A Phase I, Pharmacological, and Biological Study of OSI-774 in Combination With FOLFOX 4 (5-FU, Leucovorin, and Oxaliplatin) and Bevacizumab (Avastin) in Patients With Advanced Colorectal Cancer [Phase 1]
Phase I study evaluating the safety, pharmacology, and biology of erlotinib (OSI-774) in combination with FOLFOX-4 and bevacizumab in advanc…
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CLINICAL_TRIALS trial_result · 2013-09-30Clinical Trial Update: Suberoylanilide Hydroxamic Acid, Fluorouracil, Leucovorin, and Oxaliplatin in Treating Patients With Progressive Metastatic or Unresectable Colorectal Cancer or Other Solid Tumors [Phase 1]
Phase 1 study evaluating a combination of vorinostat (suberoylanilide hydroxamic acid) with fluorouracil, leucovorin, and oxaliplatin in pat…