Colorectal Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2015-05-22Clinical Trial Update: CROSSROAD II: Activating Rural Clinics and Women With Disabilities to Improve Cancer Screening
The CROSSROAD II trial, which aimed to activate rural clinics and support women with disabilities to improve breast, cervical, and colorecta…
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CLINICAL_TRIALS withdrawal · 2015-05-22Clinical Trial Update: FOLFOX6 Plus Sir-Spheres Microspheres Plus Avastin in Patients With Nonresectable Liver Metastases From Colorectal Carcinoma [Phase 2, Phase 3]
A Phase 2/3 trial evaluating FOLFOX6 plus Sir-Spheres microspheres and Avastin for nonresectable liver metastases from colorectal cancer has…
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CLINICAL_TRIALS trial_result · 2015-05-19Clinical Trial Update: Feasibility Study of SOL (S-1,Oral Leucovorin,and Oxaliplatin) for Colorectal Cancer in China [Phase 1, Phase 2]
Phase 1/2 feasibility study of SOL (S-1, oral leucovorin, and oxaliplatin) for colorectal cancer in China has completed.
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CLINICAL_TRIALS research · 2015-05-19Clinical Trial Update: An Observational Study of Bevacizumab in Chinese Patients With Metastatic Colorectal Cancer
This document reports an observational study evaluating the use of bevacizumab in Chinese patients with metastatic colorectal cancer.
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CLINICAL_TRIALS trial_result · 2015-05-18Clinical Trial Update: Phase I Study of Cetuximab With RO4929097 in Metastatic Colorectal Cancer [Phase 1]
Phase I study evaluating cetuximab in combination with RO4929097 for metastatic colorectal cancer was terminated.
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CLINICAL_TRIALS trial_result · 2015-05-15Clinical Trial Update: Phase I/Randomized Phase II Study of Second Line Therapy With Irinotecan + Cetuximab +/- RAD001 for Colorectal Cancer [Phase 1, Phase 2]
This completed Phase I/Phase II randomized trial evaluated second-line therapy for colorectal cancer using irinotecan and cetuximab with or …
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CLINICAL_TRIALS trial_result · 2015-05-14Clinical Trial Update: Study Evaluating the Safety and Efficacy of FOLFIRI Plus Cetuximab or FOLFOX Plus Cetuximab as First-line Therapy in Subjects With KRAS Wild-type Metastatic Colorectal Cancer (APEC-Study) [Phase 1, Phase 2]
A phase 1/2 trial evaluating first-line cetuximab-containing regimens (FOLFIRI or FOLFOX) in KRAS wild-type metastatic colorectal cancer; th…
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CLINICAL_TRIALS trial_result · 2015-05-14Clinical Trial Update: Effect of Annona Muricata Leaves on Colorectal Cancer Patients and Colorectal Cancer Cells [EARLY_Phase 1]
Early Phase 1 clinical trial investigated the effects of Annona muricata leaf extract on colorectal cancer patients and colorectal cancer ce…
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CLINICAL_TRIALS trial_result · 2015-05-13Clinical Trial Update: A Phase II Trial of MB-6 Plus FOLFOX4 for Metastatic Colorectal Cancer (FDA IND 103675) [Phase 2]
This document reports the completion of a Phase II trial evaluating MB-6 in combination with FOLFOX4 for metastatic colorectal cancer and no…
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CLINICAL_TRIALS trial_result · 2015-05-13Clinical Trial Update: Multi-marker Stool Test for Detection of Colorectal Neoplasia: Marker Panel Selection and Technical Development Studies
A completed clinical trial update reports the selection and development of a multi-marker stool test panel for detecting colorectal neoplasi…
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CLINICAL_TRIALS trial_result · 2015-05-13Clinical Trial Update: Observational Study on Second Line Treatment of Liver Metastases With DEBIRI and Cetuximab
Observational trial update examining second-line treatment of colorectal cancer liver metastases with DEBIRI and cetuximab; the study status…
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CLINICAL_TRIALS trial_result · 2015-05-13Clinical Trial Update: Real-Time Characterizations of Diminutive Colorectal Polyps Using Narrow Band Imaging
This completed clinical trial evaluated real-time characterization of diminutive colorectal polyps using narrow band imaging to improve diag…
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CLINICAL_TRIALS trial_result · 2015-05-13Clinical Trial Update: Exact CRC Screening Test: Stool Sample Collection Study to Support Assay Validation Testing
Exact Sciences reports completion of a stool-based colorectal cancer screening study intended to validate the Exact CRC assay.
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CLINICAL_TRIALS trial_result · 2015-05-12Clinical Trial Update: Peptide Vaccine and S-1/CPT-11 Therapy for Patients With Unresectable Advanced Colorectal Cancer [Phase 1]
Phase 1 trial evaluating a peptide vaccine in combination with S-1 and irinotecan (CPT-11) for unresectable advanced colorectal cancer has c…
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CLINICAL_TRIALS trial_result · 2015-05-08Clinical Trial Update: An Observational Pilot Study Evaluating the Feasibility of Conducting Genome-Wide Association Studies Utilizing Subject Provided Information in Subjects With Locally Recurrent or MBC, MCRC, MNSCLC, RGBM or MRCC Treated With Avastin (Bevacizumab) (InVite)
This completed observational pilot trial evaluated the feasibility of conducting genome-wide association studies using subject-provided info…
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CLINICAL_TRIALS trial_result · 2015-05-07Clinical Trial Update: Surgery Plus Sulindac or Surgery Alone for Advanced Colorectal Cancer [Phase 2]
Phase 2 trial evaluating surgery with or without sulindac in advanced colorectal cancer with liver metastases. The study was terminated and …
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CLINICAL_TRIALS research · 2015-05-07Clinical Trial Update: Study to Evaluate the Efficacy and Safety of FOLFIRI-AD in Patients With Metastatic Colorectal Cancer UGT1A Genotype 1 [Phase 2]
Phase 2 clinical trial evaluating FOLFIRI-AD in metastatic colorectal cancer with UGT1A genotype 1; current status is unknown.
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CLINICAL_TRIALS withdrawal · 2015-05-06Clinical Trial Update: Ziv-Aflibercept Followed by Ziv-Aflibercept, Fluorouracil, and Leucovorin Calcium in Treating Patients With Stage IV Colorectal Cancer [Phase 2]
A Phase 2 clinical trial evaluating Ziv-Aflibercept with fluorouracil and leucovorin for Stage IV colorectal cancer has been withdrawn.
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CLINICAL_TRIALS research · 2015-05-06Clinical Trial Update: Peripheral Blood DNA Methylation Markers for the Early Detection of Colorectal Carcinoma in the Egyptian Population
A completed Cairo University study evaluated peripheral blood DNA methylation markers for early detection of colorectal cancer in the Egypti…
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CLINICAL_TRIALS trial_result · 2015-05-05Clinical Trial Update: Endo-Laparoscopic Approach Versus Conventional Open Surgery in Obstructing Left-sided Colon Cancer: RCT [Phase 4]
A Phase 4 randomized trial evaluating endo-laparoscopic versus conventional open surgery for obstructing left-sided colon cancer has been co…
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FDA approval · 2015-05-04FDA Approved: OXALIPLATIN — Supplemental Application (Fresenius Kabi USA, LLC)
FDA approved a supplemental application for a generic Oxaliplatin product from Fresenius Kabi USA, LLC. This approval permits marketing of t…
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CLINICAL_TRIALS trial_result · 2015-04-29Clinical Trial Update: LMB-9 Immunotoxin in Treating Patients With Advanced Solid Tumors [Phase 1]
Phase 1 trial update on LMB-9 immunotoxin in patients with advanced solid tumors. The study has completed and includes bladder cancer, breas…
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CLINICAL_TRIALS trial_result · 2015-04-29Clinical Trial Update: Oxaliplatin Plus Capecitabine in Treating Patients With Colorectal, Appendix, or Small Bowel Cancer [Phase 1]
Phase 1 trial evaluating the combination of oxaliplatin and capecitabine in patients with colorectal cancer, appendiceal cancer, or small in…
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CLINICAL_TRIALS research · 2015-04-29Clinical Trial Update: Trial of FOLF(HA)Iri Versus FOLFIRI in mCRC [Phase 3]
This document provides a clinical trial update on a Phase 3 study comparing FOLF(HA)Iri to FOLFIRI in metastatic colorectal cancer.
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CLINICAL_TRIALS trial_result · 2015-04-29Clinical Trial Update: Profile of Soluble and Cellular Biomarkers and of Functional Imaging During Antiangiogenic Therapies in Cancer Patients
A terminated clinical trial update studying soluble and cellular biomarkers and functional imaging during antiangiogenic therapies in cancer…