Colorectal Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial [Phase 3]
Phase 3 clinical trial evaluating whether pump chemotherapy added to standard chemotherapy improves outcomes for patients with unresectable …
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: A Phase II Trial of Neoadjuvant PD-1 Vaccine PD1-Vaxx in Operable MSI High Colorectal Cancer [Phase 2]
A Phase II neoadjuvant trial evaluating the PD-1 vaccine PD1-Vaxx in operable MSI-high colorectal cancer is currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-03-20Clinical Trial Update: Capecitabine/Oxaliplatin Chemotherapy and Cemiplimab With or Without Fianlimab or REGN7075 in Locally Advanced Rectal Cancer [Phase 2]
A Phase 2 trial is evaluating capecitabine/oxaliplatin chemotherapy with cemiplimab, with or without fianlimab or REGN7075, in locally advan…
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: Using Healthy Gut Bacteria to Boost Immune Treatment for Advanced Bowel Cancer [EARLY_Phase 1]
A Phase 1 clinical trial is exploring whether healthy gut bacteria via fecal microbiota transplantation can boost immune therapy for metasta…
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CLINICAL_TRIALS trial_result · 2026-03-20Clinical Trial Update: Social Media and Cancer Screening Information [NA]
This update reports the completion of a clinical trial evaluating the impact of social media information on colorectal cancer screening upta…
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CLINICAL_TRIALS trial_result · 2026-03-20Clinical Trial Update: Randomized Controlled Trial Comparing Adult to Pediatric Colonoscope in Obese Patients. [NA]
This completed randomized trial compared adult versus pediatric colonoscopes in obese adults undergoing screening colonoscopy; results have …
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CLINICAL_TRIALS other · 2026-03-20Clinical Trial Update: Phase 2, Single-arm Trial of BMS-986340 in Association With Nivolumab, Trifluridine/Tipiracil and Bevacizumab for Patients Refractory to Standard of Care Treatment and With Microsatellite-stable Colorectal Cancer [Phase 2]
Phase 2 single-arm trial of BMS-986340 in combination with nivolumab, trifluridine/tipiracil, and bevacizumab for microsatellite-stable colo…
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CLINICAL_TRIALS trial_result · 2026-03-19Clinical Trial Update: Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12D Variant of Mutated RAS in HLA-A*11:01 Patients [Phase 1, Phase 2]
This update reports on a Phase 1/2 trial of peripheral blood lymphocytes transduced with a murine T-cell receptor recognizing the G12D varia…
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CLINICAL_TRIALS trial_result · 2026-03-19Clinical Trial Update: Role of Indexed Oxygen Delivery in Anastomotic Insufficiencies in Elective Laparoscopic Colorectal Resections for Cancer
A completed clinical trial evaluating indexed oxygen delivery to reduce anastomotic insufficiencies after elective laparoscopic colorectal c…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Shield Post-Approval Study Protocol
This document outlines the SHIELD post-approval study protocol for colorectal cancer and notes that recruitment is ongoing.
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: A Study of Tucidinostat in Combination With Sintilimab and Bevacizumab in MSS/pMMR Colorectal Cancer Patients [Phase 3]
Phase 3 clinical trial evaluating tucidinostat in combination with sintilimab and bevacizumab for MSS/pMMR colorectal cancer; currently recr…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Microbiome Testing for the Screening of Colorectal Cancer
A clinical trial is currently recruiting to evaluate microbiome-based testing as a screening tool for colorectal cancer.
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: A Study to Investigate ALE.P03 as Monotherapy in Adult Patients With Selected Advanced or Metastatic CLDN1+ Solid Tumors [Phase 1, Phase 2]
A Phase 1/2 clinical trial update shows ALE.P03 as monotherapy being studied in adults with selected advanced or metastatic CLDN1+ solid tum…
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CLINICAL_TRIALS trial_result · 2026-03-19Clinical Trial Update: Ultrasound for the Detection of Oxaliplatin-Induced Peripheral Neuropathy [NA]
A completed study evaluating ultrasound as a method to detect oxaliplatin-induced peripheral neuropathy in patients with gastrointestinal or…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Camera Capsule Endoscopy in the Routine Diagnostic Pathway for Colorectal Diseases [NA]
A clinical trial evaluating camera capsule endoscopy in the routine diagnostic pathway for colorectal diseases, including colorectal cancer,…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Stereotactic Brain-directed Radiation With or Without Aguix Gadolinium-Based Nanoparticles in Brain Metastases [Phase 2]
Phase 2 trial evaluating stereotactic brain-directed radiation with or without Aguix gadolinium-based nanoparticles for brain metastases; th…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Study of Dato-DXd as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Tumours (TROPION-PanTumor03) [Phase 2]
AstraZeneca's Dato-DXd is being studied as a single agent and in combination with other anti-cancer drugs in an ongoing Phase 2 trial for ad…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: A Clinical Study to Evaluate Injection TQB2102 for the Treatment of Patients With HER2 IHC3+ Advanced Colorectal Cancer Who Progressed After Treatment With Oxaliplatin, Irinotecan and Fluoropyrimidine-Based Drugs [Phase 3]
This document details a Phase 3 clinical trial evaluating injection TQB2102 for HER2 IHC3+ advanced colorectal cancer that progressed after …
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Histotripsy Plus Chemotherapy vs Chemotherapy Alone for Advanced Colorectal Liver Metastasis [NA]
A clinical trial is evaluating histotripsy in combination with chemotherapy versus chemotherapy alone for advanced colorectal cancer with li…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: INFINITIVE: ImmuNotherapy For PatIeNts wIth colorecTal LIVer MEtastases [EARLY_Phase 1]
An early-phase trial evaluating INFINITIVE immunotherapy for metastatic colorectal cancer with liver metastases, currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-03-19Clinical Trial Update: Pressure-enabled Delivery in Radioembolization (TriNav Study) [NA]
The TriNav study, led by Massachusetts General Hospital, is evaluating pressure-enabled delivery in radioembolization for liver cancers; the…
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EMA approval · 2026-03-18EMA Authorised: Opdivo (nivolumab) — Bristol-Myers Squibb Pharma EEIG
EMA authorised Opdivo (nivolumab) for multiple cancer indications, including melanoma, Hodgkin lymphoma, renal cell carcinoma, non-small cel…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: A Trial of RSC-1255 for Treatment of Patients With Advanced Malignancies [Phase 1]
Phase 1 clinical trial evaluating RSC-1255 in patients with advanced malignancies carrying RAS mutations, sponsored by RasCal Therapeutics, …
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: A First-in-human Study of BGB-53038, a Pan-KRAS Inhibitor, Alone or in Combinations in Participants With Advanced or Metastatic Solid Tumors With KRAS Mutations or Amplification [Phase 1]
BeiGene is conducting a first-in-human Phase 1 study of BGB-53038, a pan-KRAS inhibitor, as a monotherapy or in combination, in participants…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Prospective Clinical Validation of Next Generation Sequencing (NGS) and Patient-Derived Tumor Organoids (PDO) Guided Therapy in Patients With Advanced/ Inoperable Solid Tumors [NA]
This document outlines a prospective clinical validation trial using next-generation sequencing and patient-derived tumor organoids to guide…