Colorectal Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2017-11-06Clinical Trial Update: Laparoscopic Right Hemicoloectomy for Right Colon Cancer With a Medial-to-lateral Approach Orientated by SMA or SMV [Phase 2, Phase 3]
Clinical trial update describing a Phase 2/Phase 3 study evaluating laparoscopic right hemicolectomy for right colon cancer using a medial-t…
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CLINICAL_TRIALS trial_result · 2017-10-31Clinical Trial Update: S1406 Phase II Study of Irinotecan and Cetuximab With or Without Vemurafenib in BRAF Mutant Metastatic Colorectal Cancer [Phase 2]
Phase II trial evaluating irinotecan and cetuximab with or without vemurafenib in BRAF-mutant metastatic colorectal cancer has completed wit…
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CLINICAL_TRIALS trial_result · 2017-10-31Clinical Trial Update: Changes in Stem Cells of the Colon in Response to Increased Risk of Colorectal Cancer
This completed clinical trial studied changes in colon stem cells in individuals at increased risk of colorectal cancer.
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CLINICAL_TRIALS trial_result · 2017-10-27Clinical Trial Update: Phase I:Decitabine by Hepatic Arterial Infusion(HAI) in Unresectable Liver Metastases Colorectal Cancer (CRC) [Phase 1, Phase 2]
Phase I/II clinical trial of decitabine delivered by hepatic arterial infusion for unresectable liver metastases from colorectal cancer has …
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CLINICAL_TRIALS trial_result · 2017-10-27Clinical Trial Update: Quantitative Versus Qualitative Fecal Immunochemical Tests (FIT) to Prioritize Urgency of Colonoscopy Referral [NA]
This completed trial compared quantitative and qualitative fecal immunochemical tests to prioritize urgency of colonoscopy referrals for col…
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CLINICAL_TRIALS research · 2017-10-27Clinical Trial Update: Resection of Colorectal Liver Metastases With or Without Routine Hilar Lymphadenectomy [NA]
An entry describing an ongoing clinical trial comparing resection of colorectal liver metastases with versus without routine hilar lymphaden…
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CLINICAL_TRIALS research · 2017-10-26Clinical Trial Update: Evaluation of the Resection of Adenoma and Colic Adenocarcinoma by EMR Piecemeal or EMR/ESD Hybrid Technique
A clinical trial evaluating EMR piecemeal and EMR/ESD hybrid resection techniques for colorectal adenoma and intramucinous adenocarcinoma. T…
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CLINICAL_TRIALS withdrawal · 2017-10-26Clinical Trial Update: Cetuximab and Savolitinib Treatment of Ras Wild-Type Colorectal Cancer [Phase 1]
Phase 1 trial evaluating cetuximab with savolitinib in Ras wild-type colorectal cancer has been withdrawn.
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CLINICAL_TRIALS trial_result · 2017-10-24Clinical Trial Update: Clinical Trial of Combination Chemotherapy With Aflibercept in Patients With Advanced Colorectal Cancer [Phase 2]
Phase 2 clinical trial update for combination chemotherapy with aflibercept in advanced/metastatic colorectal cancer has completed.
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CLINICAL_TRIALS research · 2017-10-23Clinical Trial Update: A Single Arm, Open-label Clinical Trial to Evaluate the Efficacy and Safety of Maintenance Treatment With Capecitabine Plus Cetuximab in Metastatic Colorectal Cancer [Phase 2]
This entry covers a Phase 2, single-arm, open-label trial evaluating maintenance therapy with capecitabine plus cetuximab in metastatic colo…
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CLINICAL_TRIALS trial_result · 2017-10-20Clinical Trial Update: Colorectal Cancer Treated With Adjuvant Regorafenib Versus Placebo After Curative Treatment of Liver Metastases in a Randomized, Double-blind, Placebo-Controlled Phase-III STudy [Phase 3]
A phase 3 randomized, double-blind trial evaluating adjuvant regorafenib versus placebo after curative treatment of liver metastases in colo…
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CLINICAL_TRIALS research · 2017-10-20Clinical Trial Update: Intraoperative Testing of Colorectal Anastomosis - Air or Water (Methylene Blue)? [NA]
Meir Medical Center is conducting a clinical trial to evaluate intraoperative testing of colorectal anastomosis using air or water with meth…
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CLINICAL_TRIALS trial_result · 2017-10-19Clinical Trial Update: A Phase 4 Study of Regorafenib in Metastatic Colorectal Cancer - Does Educating Physicians Change Patient Outcomes? [Phase 4]
Phase 4 study assessing whether educating physicians changes patient outcomes in metastatic colorectal cancer patients treated with regorafe…
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CLINICAL_TRIALS trial_result · 2017-10-13Clinical Trial Update: Systems of Support (SOS) to Increase Colon Cancer Screening and Follow-up Supplement [NA]
Completed clinical trial evaluating systems-based interventions to increase colorectal cancer screening and follow-up in a Kaiser Permanente…
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CLINICAL_TRIALS research · 2017-10-13Clinical Trial Update: Feasibility of Quality of Life Assessment in Routine Clinical Oncology Practice at the University Hospital of Besancon [NA]
A clinical trial update assessing the feasibility of incorporating quality-of-life assessments into routine oncology practice at the Univers…
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CLINICAL_TRIALS research · 2017-10-13Clinical Trial Update: Molecular Pathology of Colorectal Cancer: Investigating the Role of Novel Molecular Profiles, microRNA's, and Their Targets in Colorectal Cancer Progression
An update describing a colorectal cancer clinical trial focused on novel molecular profiles and microRNA targets in cancer progression.
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CLINICAL_TRIALS trial_result · 2017-10-09Clinical Trial Update: Study of WNT974 in Combination With LGX818 and Cetuximab in Patients With BRAF-mutant Metastatic Colorectal Cancer (mCRC) and Wnt Pathway Mutations [Phase 1, Phase 2]
This is a completed Phase 1/2 clinical trial investigating WNT974 in combination with LGX818 and cetuximab in patients with BRAF-mutant meta…
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CLINICAL_TRIALS trial_result · 2017-09-28Clinical Trial Update: Polyphenon E in Treating Patients With High-Risk of Colorectal Cancer [Phase 2]
A Phase 2 trial of Polyphenon E for patients at high risk of colorectal cancer, including advanced colorectal adenomas and colon cancer, was…
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CLINICAL_TRIALS trial_result · 2017-09-28Clinical Trial Update: NEOadjuvant Chemotherapy Only Compared With Standard Treatment for Locally Advanced Rectal Cancer [Phase 2]
Phase 2 trial comparing neoadjuvant chemotherapy-only regimen to standard treatment for locally advanced rectal cancer; status currently unk…
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CLINICAL_TRIALS trial_result · 2017-09-18Clinical Trial Update: Exercise and Metformin in Colorectal and Breast Cancer Survivors [Phase 2]
Phase 2 clinical trial update evaluating exercise plus metformin in colorectal and breast cancer survivors. The study is completed and resul…
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CLINICAL_TRIALS trial_result · 2017-09-18Clinical Trial Update: Sequential and Concurrent FOLFOXIRI/Bevacizumab Regimens Versus FOLFOX/Bevacizumab in First-Line Metastatic Colorectal Cancer [Phase 2]
Phase 2 trial comparing sequential and concurrent FOLFOXIRI/Bevacizumab regimens versus FOLFOX/Bevacizumab as first-line therapy in metastat…
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CLINICAL_TRIALS research · 2017-09-15Clinical Trial Update: Decision Aid to Technologically Enhance Shared Decision Making [NA]
A completed clinical trial evaluating a decision aid to enhance shared decision making for colorectal cancer patients; results posted in 201…
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FDA approval · 2017-09-14FDA Approved: MVASI — Original Application (Amgen, Inc)
The FDA approved MVASI (bevacizumab-awwb) from Amgen as a biosimilar to Avastin, marking the original application granting U.S. approval for…
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CLINICAL_TRIALS trial_result · 2017-09-14Clinical Trial Update: A Phase II Study of the Safety and Efficacy of E7820 Plus Cetuximab in Colorectal Cancer, Preceded by a Run-in Study in Advanced Solid Tumors [Phase 2]
Phase II study exploring safety and efficacy of E7820 plus cetuximab in advanced colorectal cancer; run-in study in advanced solid tumors co…
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CLINICAL_TRIALS withdrawal · 2017-08-31Clinical Trial Update: Trial of Aflibercept Monotherapy With DCE-US in Chemorefractory Metastatic Colorectal Cancer [Phase 2]
A Phase 2 trial of aflibercept monotherapy with DCE-US for chemorefractory metastatic colorectal cancer has been withdrawn.