Colorectal Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2022-05-06Clinical Trial Update: Morphotek Investigation in Colorectal Cancer: Research of MORAb-004 (MICRO) [Phase 2]
Phase 2 trial of MORAb-004 (MICRO) in colorectal cancer was terminated; results posted in 2022.
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CLINICAL_TRIALS trial_result · 2022-05-05Clinical Trial Update: mFOLXOX6 Versus FOLFIRI for Colorectal Patients Recurrence After Oxaplatin Based Adjuvant Chemotherapy [Phase 3]
A Phase 3 clinical trial comparing mFOLXOX6 to FOLFIRI for metastatic colorectal cancer after oxaliplatin-based adjuvant therapy.
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CLINICAL_TRIALS trial_result · 2022-05-05Clinical Trial Update: Avelumab Plus Cetuximab in Pre-treated RAS Wild Type Metastatic Colorectal Cancer [Phase 2]
Phase 2 trial evaluating avelumab plus cetuximab in pre-treated RAS wild type metastatic colorectal cancer has completed.
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CLINICAL_TRIALS trial_result · 2022-05-02Clinical Trial Update: Clinical Efficacy and Safety of NKT Cell Infusion in Patients With Advanced Solid Tumor [Phase 1, Phase 2]
Phase 1/2 trial update evaluating NKT cell infusion for advanced solid tumors, with indications including non-small cell lung cancer and gas…
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CLINICAL_TRIALS trial_result · 2022-04-29Clinical Trial Update: Preoperative Systemic Therapy for Colorectal Cancer Peritoneal Metastases [Phase 2]
Phase 2 trial update on preoperative systemic therapy for colorectal cancer with peritoneal metastases.
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CLINICAL_TRIALS trial_result · 2022-04-29Clinical Trial Update: Impact of FOLFIRINOX Chemotherapy in IV Stage Colorectal Cancer Patients Previously Exposed to Irinotecan, Fluoropyrimidine and Oxaliplatin [Phase 2]
A Phase 2 trial evaluating the impact of FOLFIRINOX chemotherapy in stage IV colorectal cancer patients previously exposed to irinotecan, fl…
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CLINICAL_TRIALS trial_result · 2022-04-26Clinical Trial Update: A Study of Napabucasin (BBI-608) in Combination With FOLFIRI in Adult Patients With Previously Treated Metastatic Colorectal Cancer [Phase 3]
Phase 3 trial updating napabucasin (BBI-608) with FOLFIRI in previously treated metastatic colorectal cancer has completed; results posted.
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CLINICAL_TRIALS trial_result · 2022-04-22Clinical Trial Update: An Exploratory Study of Sequential Transarterial Chemoembolization With Lipiodol and Neoadjuvant Chemotherapy in the Treatment of Initial Unresectable Colorectal Cancer (CRC) [Phase 2]
Phase 2 exploratory trial evaluating sequential transarterial chemoembolization with Lipiodol followed by neoadjuvant chemotherapy for initi…
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CLINICAL_TRIALS trial_result · 2022-04-20Clinical Trial Update: Bevacizumab and Combination Chemotherapy as First-Line Therapy in Treating Patients With Metastatic Colorectal Cancer That Cannot Be Removed by Surgery [Phase 2]
Phase 2 trial evaluating bevacizumab with combination chemotherapy as first-line therapy for unresectable metastatic colorectal cancer. Comp…
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CLINICAL_TRIALS trial_result · 2022-04-14Clinical Trial Update: PolyPEPI1018 Vaccine and CDx for the Treatment of Metastatic Colorectal Cancer (OBERTO) [Phase 1, Phase 2]
Phase 1/2 clinical trial update for PolyPEPI1018 vaccine with companion diagnostic in metastatic colorectal cancer has completed with result…
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CLINICAL_TRIALS trial_result · 2022-04-14Clinical Trial Update: Possible Protective Effect of Celecoxib Against Capecitabine Induced Hand and Foot Syndrome in Patients With Colorectal Cancer [Phase 3]
Phase 3 trial investigating whether celecoxib can protect against capecitabine-induced hand and foot syndrome in colorectal cancer patients.
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CLINICAL_TRIALS trial_result · 2022-04-14Clinical Trial Update: Study for Evaluation of Murlentamab (GM102) Anti-tumoral Activity in Colorectal Cancers [Phase 2]
Phase 2 trial evaluating murlentamab (GM102) anti-tumoral activity in colorectal cancer has completed.
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FDA approval · 2022-04-13FDA Approved: ALYMSYS — Original Application (Amneal Pharmaceuticals LLC)
FDA approves ALYMSYS as a biosimilar to bevacizumab (bevaczizumab-maly) from Amneal Pharmaceuticals LLC under an original Biologics License …
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CLINICAL_TRIALS trial_result · 2022-04-08Clinical Trial Update: Phase 1 Trial To Evaluate mFOLFOX6 With Selinexor In Patients With Metastatic Colorectal Cancer [Phase 1]
Phase 1 trial evaluating mFOLFOX6 with selinexor in metastatic colorectal cancer has been terminated; results posted in 2022.
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CLINICAL_TRIALS trial_result · 2022-04-07Clinical Trial Update: Intermittent or Continuous Panitumumab Plus FOLFIRI for RAS/B-RAF Wild-type Metastatic Colorectal Cancer [Phase 2]
Phase 2 trial evaluating intermittent or continuous panitumumab plus FOLFIRI in RAS/B-RAF wild-type metastatic colorectal cancer has complet…
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CLINICAL_TRIALS trial_result · 2022-04-07Clinical Trial Update: Triplet (FOLFOXIRI) vs. Doublet (FOLFOX or FOLFIRI) Regimen as a 1st Line Treatment in Metastatic Colorectal Carcinoma [Phase 2]
Phase 2 trial comparing triplet FOLFOXIRI to doublet FOLFOX or FOLFIRI as first-line treatment for metastatic colorectal cancer has been com…
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CLINICAL_TRIALS trial_result · 2022-04-06Clinical Trial Update: Re-challenge Therapy With Chemotherapy & Panitumumab in Metastatic Colorectal Cancer Patients Treated With an Anti-EGFR [Phase 2]
Phase 2 clinical trial evaluating re-challenge therapy with chemotherapy and panitumumab in metastatic colorectal cancer patients previously…
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CLINICAL_TRIALS trial_result · 2022-04-05Clinical Trial Update: Impact of Intraoperative Deep Neuromuscular Blockade on NOL-guided Opioid Requirement in LSC Colorectal Surgeries [Phase 4]
A Phase 4 clinical trial updating how intraoperative deep neuromuscular blockade affects NOL-guided opioid requirements in laparoscopic colo…
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CLINICAL_TRIALS trial_result · 2022-04-04Clinical Trial Update: NIVOLUMAB Plus IPILIMUMAB and TEMOZOLOMIDE in Microsatellite Stable, MGMT Silenced Metastatic Colorectal Cancer [Phase 2]
Phase 2 trial evaluating nivolumab plus ipilimumab with temozolomide in microsatellite-stable, MGMT-silenced metastatic colorectal cancer ha…
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CLINICAL_TRIALS trial_result · 2022-03-31Clinical Trial Update: Radiotherapy in Combination With Sintilimab，GM-CSF and Fruquintinib in Patients With MSS mCRC [Phase 2]
Phase 2 trial evaluating radiotherapy in combination with sintilimab, GM-CSF, and fruquintinib in patients with metastatic microsatellite-st…
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CLINICAL_TRIALS trial_result · 2022-03-31Clinical Trial Update: Chemoprophylaxis With Rivaroxaban for Lower Limb Deep Vein Thrombosis in Colorectal Cancer [Phase 4]
Phase 4 trial update on rivaroxaban as chemoprophylaxis for lower limb deep vein thrombosis in patients with colorectal cancer.
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CLINICAL_TRIALS trial_result · 2022-03-31Clinical Trial Update: Avastin/FOLFIRI in Combination With Curcumin in Colorectal Cancer Patients With Unresectable Metastasis [Phase 2]
A Phase 2 trial evaluating Avastin/FOLFIRI with curcumin in colorectal cancer with unresectable metastases has completed.
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CLINICAL_TRIALS trial_result · 2022-03-31Clinical Trial Update: Study of Neratinib +Trastuzumab or Neratinib + Cetuximab in Patients With KRAS/NRAS/BRAF/PIK3CA Wild-Type Metastatic Colorectal Cancer by HER2 Status [Phase 2]
Phase 2 study evaluating neratinib in combination with trastuzumab or cetuximab for metastatic colorectal cancer with wild-type KRAS/NRAS/BR…
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CLINICAL_TRIALS trial_result · 2022-03-24Clinical Trial Update: Treatment After Irinotecan-based Frontline Therapy: Maintenance With Erbitux (in Patients wtRAS mCRC) [Phase 2]
Phase 2 trial evaluating maintenance Erbitux after irinotecan-based frontline therapy in patients with wild-type RAS metastatic colorectal c…
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CLINICAL_TRIALS trial_result · 2022-03-23Clinical Trial Update: Study of Vitamin D in Untreated Metastatic Colorectal Cancer [Phase 2]
A Phase 2 trial evaluating vitamin D in untreated metastatic colorectal cancer has completed with posted results.