Colorectal Cancer
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Sign up freeTop drugs studied for this disease
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FDA approval · 2022-09-14FDA Approved: FLUOROURACIL — Supplemental Application (BluePoint Laboratories)
FDA approved a supplemental application for fluorouracil submitted by BluePoint Laboratories, indicating approval of an ANDA supplement. Thi…
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CLINICAL_TRIALS research · 2022-09-09Clinical Trial Update: Study of Tivantinib (ARQ 197) Plus Cetuximab in EGFR Inhibitor-Resistant MET High Subjects [Phase 2]
Phase 2 trial evaluating tivantinib plus cetuximab in EGFR inhibitor-resistant, MET-high metastatic colorectal cancer.
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CLINICAL_TRIALS research · 2022-09-09Clinical Trial Update: Two Low Volume Regimens for Colorectal Cancer Screening Colonoscopy [Phase 4]
A Phase 4 clinical trial update evaluating two low-volume regimens for colorectal cancer screening colonoscopy has been completed.
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CLINICAL_TRIALS trial_result · 2022-09-08Clinical Trial Update: Nivolumab+Ipilimumab+RT in MSS mCRC [Phase 2]
Phase 2 trial update examining nivolumab + ipilimumab + radiotherapy in metastatic microsatellite stable colorectal cancer.
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CLINICAL_TRIALS trial_result · 2022-09-02Clinical Trial Update: Temozolomide and Irinotecan in Patients With MGMT Silenced Colorectal Cancer After Adjuvant Chemotherapy [Phase 2]
Phase 2 trial investigating temozolomide and irinotecan in MGMT-silenced colorectal cancer after adjuvant chemotherapy.
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CLINICAL_TRIALS trial_result · 2022-09-01Clinical Trial Update: Sintilimab Combined With Regorafenib and HAIC in Patients With Colorectal Liver Metastasis [Phase 2]
A Phase 2 trial evaluating sintilimab combined with regorafenib and hepatic arterial infusion chemotherapy (HAIC) in patients with colorecta…
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CLINICAL_TRIALS trial_result · 2022-09-01Clinical Trial Update: Evaluation of EverLift in the Performance of Polypectomy for Polyps 4-9mm [NA]
Clinical trial updating evaluation of EverLift for polypectomy in 4-9 mm polyps; completed with results posted.
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CLINICAL_TRIALS trial_result · 2022-09-01Clinical Trial Update: Effect of Hemp-CBD on Patients With CIPN [Phase 2]
Phase 2 clinical trial investigating the effect of hemp-derived CBD on chemotherapy-induced peripheral neuropathy.
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CLINICAL_TRIALS trial_result · 2022-08-30Clinical Trial Update: Encorafenib, Binimetinib and Cetuximab in Subjects With Previously Untreated BRAF-mutant ColoRectal Cancer [Phase 2]
Phase 2 trial updates the efficacy/safety of encorafenib, binimetinib, and cetuximab in previously untreated BRAF V600E-mutant metastatic co…
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CLINICAL_TRIALS trial_result · 2022-08-25Clinical Trial Update: Rechallenge With Panitumumab Driven by RAS Dynamic of Resistance [Phase 2]
Phase 2 trial evaluating rechallenge with panitumumab guided by RAS dynamic resistance in colorectal cancer has completed.
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CLINICAL_TRIALS trial_result · 2022-08-23Clinical Trial Update: TAS-102 Combined With Bevacizumab and Tislelizumab Third-line or Above in the Treatment of Liver Metastasis in Colorectal Cancer [Phase 2]
Phase 2 clinical trial evaluating TAS-102 with bevacizumab and tislelizumab in third-line or earlier for colorectal cancer with liver metast…
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CLINICAL_TRIALS trial_result · 2022-08-22Clinical Trial Update: A Prospective Multi-centered Randomized Controlled Trial on Fruquintinib in Combination With HAIC in the Treatment of Liver Metastatic Colorectal Cancer After Failure of Second-line Systematic Therapy [Phase 2]
Phase 2 randomized trial evaluating Fruquintinib with hepatic arterial infusion in liver-metastatic colorectal cancer after second-line ther…
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CLINICAL_TRIALS trial_result · 2022-08-22Clinical Trial Update: Virtual Reality for Improving Pain and Distress in Patients With Advanced Stage Colorectal Cancer [NA]
Clinical trial assessing virtual reality to alleviate pain and distress in advanced colorectal cancer patients has completed with results po…
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CLINICAL_TRIALS trial_result · 2022-08-19Clinical Trial Update: Safety Study of DNA Vaccine Delivered by Intradermal Electroporation to Treat Colorectal Cancer [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating an intradermal electroporation-delivered DNA vaccine for colorectal cancer has completed.
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CLINICAL_TRIALS trial_result · 2022-08-18Clinical Trial Update: A Safety and Activity Study of SBT6050 in Combination With Other HER2-directed Therapies for HER2-positive Cancers [Phase 1, Phase 2]
Phase 1/2 safety and activity study of SBT6050 in combination with other HER2-directed therapies for HER2-positive cancers; the trial status…
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CLINICAL_TRIALS trial_result · 2022-08-18Clinical Trial Update: Fruquintinib Plus Capecitabine as Maintenance Treatment of RAS / BRAF Wild-type Metastatic Colorectal Cancer [Phase 1, Phase 2]
A clinical trial exploring fruquintinib plus capecitabine as maintenance therapy for metastatic colorectal cancer with RAS/BRAF wild-type st…
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CLINICAL_TRIALS trial_result · 2022-08-18Clinical Trial Update: Fruquintinib Combined With TAS-102 in the Treatment of Patients With Advanced Metastatic CRC [Phase 2]
Phase 2 trial investigating fruquintinib in combination with TAS-102 for metastatic colorectal cancer.
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CLINICAL_TRIALS trial_result · 2022-08-18Clinical Trial Update: A Phase II Study of Fruquintinib Combined With Capecitabine as First-line Treatment for Advanced Metastatic Colorectal Cancer Unsuitable for Intravenous Chemotherapy [Phase 2]
A Phase II study evaluating fruquintinib in combination with capecitabine as first-line therapy for advanced/metastatic colorectal cancer un…
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CLINICAL_TRIALS trial_result · 2022-08-17Clinical Trial Update: Tislelizumab Combined With Fruquintinib and SBRT as Athird-line and Posterior Line Treatment in Patients With Advanced CRC [Phase 2]
Phase 2 trial investigating tislelizumab combined with fruquintinib and SBRT as third- to posterior-line therapy in advanced metastatic colo…
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CLINICAL_TRIALS trial_result · 2022-08-03Clinical Trial Update: Phase II Study of Regorafenib and Toripalimab Combined With RFA in Patients With CRCLM [Phase 2]
Phase II clinical trial investigating regorafenib plus toripalimab with radiofrequency ablation in colorectal cancer liver metastases.
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CLINICAL_TRIALS trial_result · 2022-07-27Clinical Trial Update: A Research of Berberine Hydrochloride to Prevent Colorectal Adenomas in Patients With Previous Colorectal Cancer [Phase 2, Phase 3]
A Phase 2/3 clinical trial evaluating berberine hydrochloride for prevention of colorectal adenomas in patients with previous colorectal can…
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CLINICAL_TRIALS trial_result · 2022-07-26Clinical Trial Update: ImmunoTEP With 68-Ga in Metastatic Colo Rectal Cancer [Phase 2]
Phase 2 trial update for ImmunoTEP with 68-Ga in metastatic colorectal cancer. Study completed.
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CLINICAL_TRIALS trial_result · 2022-07-26Clinical Trial Update: Fruquintinib Plus Capecitabine Versus Bevacizumab Plus Capecitabine as Maintenance Therapy Following First-line Treatment for Metastatic Colorectal Cancer [Phase 2]
Phase 2 trial comparing Fruquintinib plus capecitabine versus Bevacizumab plus capecitabine as maintenance therapy after first-line treatmen…
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CLINICAL_TRIALS trial_result · 2022-07-25Clinical Trial Update: Fruquitinib Combined With Camrelizumab in Non MSI-H/dMMR Refractory Colorectal Cancer [Phase 2]
Phase 2 trial evaluating fruquitinib combined with camrelizumab in refractory colorectal cancer that is non MSI-H/dMMR.
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CLINICAL_TRIALS trial_result · 2022-07-21Clinical Trial Update: Cetuximab in Combination With Anti-PD-1 and mFOLFOX Treat For RAS/BRAF wt Right-Sided Colon Cancer [Phase 2]
Phase 2 trial update on cetuximab combined with anti-PD-1 and mFOLFOX for RAS/BRAF wild-type right-sided colon cancer.