Colorectal Cancer

• CLINICAL_TRIALS trial_result · 2023-02-14
  Clinical Trial Update: Efficacy and Safety of Sintilimab Combined With Regorafenib and Cetuximab / Sintilimab Combined With Regorafenib in Posterior Line Therapy of Advanced Colorectal Cancer (Regosinti) [Phase 2]

  Phase 2 trial evaluating sintilimab combined with regorafenib and cetuximab for advanced colorectal cancer (mCRC) with intermediate status.

• CLINICAL_TRIALS trial_result · 2023-02-13
  Clinical Trial Update: Molecular Targeting of 15-Lipoxygenase-1 (15-LOX-1) for Apoptosis Induction in Human Colorectal Cancers [Phase 2]

  Phase 2 trial investigating molecular targeting of 15-LOX-1 to induce apoptosis in colorectal cancers associated with familial adenomatous p…

• CLINICAL_TRIALS trial_result · 2023-02-10
  Clinical Trial Update: Evaluation of the Safety and the Tolerability of Durvalumab Plus Tremelimumab Combined With FOLFOX in mCRC [Phase 1, Phase 2]

  Phase 1/2 clinical trial evaluating safety and tolerability of durvalumab plus tremelimumab with FOLFOX in metastatic colorectal cancer has …

• CLINICAL_TRIALS trial_result · 2023-02-10
  Clinical Trial Update: Efficacy, Tolerability and Safety of Intravenous D-VC With ATO in Patients With Advanced/Metastatic Colorectal Cancer [Phase 1, Phase 2]

  Clinical trial update investigating intravenous D-VC with ATO in advanced/metastatic colorectal cancer across Phase 1 and Phase 2.

• CLINICAL_TRIALS trial_result · 2023-02-01
  Clinical Trial Update: Pd1 Antibody Sintilimab ± Chemoradiotherapy for Locally Advanced Rectal Cancer [Phase 2]

  Phase 2 trial evaluating PD-1 antibody sintilimab with or without chemoradiotherapy for locally advanced colorectal cancer (Stage II/III). A…

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• CLINICAL_TRIALS trial_result · 2023-02-01
  Clinical Trial Update: A Study of Ametumumab in Combination With Anti-PD-1 Monoclonal Antibody and FOLFIRI in Patients With RAS Wild-type Advanced Colorectal Cancer [Phase 2]

  Phase 2 trial evaluating ametumumab with anti-PD-1 antibody and FOLFIRI in RAS wild-type advanced colorectal cancer.

• CLINICAL_TRIALS trial_result · 2023-01-31
  Clinical Trial Update: A Study of Navicixizumab Monotherapy or in Combination in Patients With Select Advanced Solid Tumors [Phase 2]

  Phase 2 study evaluating Navicixizumab as monotherapy or in combination in patients with select advanced solid tumors, including colorectal …

• CLINICAL_TRIALS trial_result · 2023-01-30
  Clinical Trial Update: Chemotherapy w/wo WeiLeShu in Metastatic Colorectal Cancer [Phase 2]

  Phase 2 clinical trial update on chemotherapy with or without WeiLeShu in metastatic colorectal cancer has completed.

• CLINICAL_TRIALS research · 2023-01-30
  Clinical Trial Update: TMZ + Olaparib for MGMT Hypermethylated Colorectal Cancer [Phase 2]

  Phase 2 trial update evaluating TMZ plus Olaparib for MGMT hypermethylated colorectal cancer has completed with posted results.

• CLINICAL_TRIALS trial_result · 2023-01-26
  Clinical Trial Update: CAPEOX vs Observation in Colorectal Cancer Patients With Positive MRD [Phase 3]

  A Phase 3 trial comparing CAPEOX chemotherapy versus observation in colorectal cancer patients with positive minimal residual disease (MRD).…

• CLINICAL_TRIALS trial_result · 2023-01-26
  Clinical Trial Update: FOS Immunohistochemical Staining of Colorectal Cancer and Its Adjacent Tissues [Phase 2, Phase 3]

  This clinical trial update describes immunohistochemical staining of colorectal cancer and adjacent tissues in a Phase 2/Phase 3 study.

• CLINICAL_TRIALS trial_result · 2023-01-26
  Clinical Trial Update: S1417CD Financial Impact Assessment Tool in Patients With Metastatic Colorectal Cancer

  Clinical trial update about the S1417CD Financial Impact Assessment Tool in metastatic colorectal cancer; study completed with results poste…

• CLINICAL_TRIALS trial_result · 2023-01-18
  Clinical Trial Update: Predictive Value of Drug Sensitivity Testing Tumorspheres From Patients With Metastatic Colorectal Cancer [Phase 2]

  Phase 2 trial assessing predictive value of drug sensitivity testing on tumorspheres from patients with metastatic colorectal cancer has com…

• CLINICAL_TRIALS trial_result · 2023-01-12
  Clinical Trial Update: Pilot Study of GVAX in Colorectal Cancer Cells [Phase 1]

  Phase 1 pilot study evaluating GVAX in colorectal cancer; study terminated with results posted.

• CLINICAL_TRIALS trial_result · 2023-01-10
  Clinical Trial Update: Durvalumab Plus CV301 With Maintenance Chemotherapy in Metastatic Colorectal or Pancreatic Adenocarcinoma [Phase 1, Phase 2]

  Clinical trial update for durvalumab plus CV301 with maintenance chemotherapy in metastatic colorectal or pancreatic adenocarcinoma; study s…

• CLINICAL_TRIALS trial_result · 2023-01-09
  Clinical Trial Update: Targeted Delivery of Chemotherapy With Ultrasound and Microbublles [Phase 2]

  Phase 2 trial update on targeted ultrasound and microbubble–mediated chemotherapy delivery for colorectal cancer with hepatic metastases is …

• CLINICAL_TRIALS research · 2023-01-06
  Clinical Trial Update: Alternating Treatment With Fruquintinib and Bevacizumab Plus Capecitabine as Maintenance Therapy After First-Line Treatment in Metastatic Colorectal Cancer [Phase 2]

  Phase 2 trial evaluating alternating maintenance therapy with fruquintinib and bevacizumab plus capecitabine after first-line treatment in m…

• CLINICAL_TRIALS trial_result · 2023-01-05
  Clinical Trial Update: First Line mFOLFOXIRI + PANITUMUMAB vs mFOLFOX + PANITUMUMAB IN RAS AND BRAF WT METASTATIC COLORECTAL CANCER PATIENTS [Phase 3]

  Phase 3 trial comparing first-line mFOLFOXIRI plus panitumumab versus mFOLFOX plus panitumumab in Ras and BRAF wild-type metastatic colorect…

• CLINICAL_TRIALS trial_result · 2023-01-05
  Clinical Trial Update: Assessing the Effect of a Blood-based Colorectal Cancer Screening Test on Screening Adherence and Colonoscopy Completion [NA]

  A completed clinical trial studying the impact of a blood-based colorectal cancer screening test on screening adherence and colonoscopy comp…

• CLINICAL_TRIALS trial_result · 2022-12-30
  Clinical Trial Update: PACE: PD-1 Antibody For dMMR/MSI-H Stage III Colorectal Cancer [Phase 3]

  Phase 3 trial investigating a PD-1 antibody for dMMR/MSI-H stage III colorectal cancer is currently recruiting.

• CLINICAL_TRIALS trial_result · 2022-12-29
  Clinical Trial Update: Binimetinib and Palbociclib or TAS-102 in Treating Patients With KRAS and NRAS Mutant Metastatic or Unresectable Colorectal Cancer [Phase 2]

  Phase 2 trial evaluating a triple combination of binimetinib, palbociclib, and TAS-102 in KRAS- or NRAS-mutant metastatic or unresectable co…

• CLINICAL_TRIALS trial_result · 2022-12-23
  Clinical Trial Update: Study of Pembrolizumab, Binimetinib, and Bevacizumab in Patients With Refractory Colorectal Cancer [Phase 2]

  A Phase 2 study evaluating pembrolizumab, binimetinib, and bevacizumab in patients with refractory colorectal cancer has completed. Results …

• CLINICAL_TRIALS trial_result · 2022-12-22
  Clinical Trial Update: A Study of Avastin (Bevacizumab) in Combination With Chemotherapy in Chinese Patients With Metastatic Colorectal Cancer. [Phase 3]

  Phase 3 trial updating Avastin (bevacizumab) combined with chemotherapy in Chinese patients with metastatic colorectal cancer has completed.

• CLINICAL_TRIALS trial_result · 2022-12-22
  Clinical Trial Update: A Study to Investigate ONCOS-102 in Combination With Durvalumab in Subjects With Advanced Peritoneal Malignancies [Phase 1, Phase 2]

  Phase 1/2 trial evaluating ONCOS-102 in combination with durvalumab in advanced peritoneal malignancies (colorectal, ovarian, and appendicea…

• CLINICAL_TRIALS trial_result · 2022-12-13
  Clinical Trial Update: Intratumoral Influenza Vaccine for Early Colorectal Cancer [Phase 2]

  Phase 2 trial update for an intratumoral influenza vaccine in colorectal cancer has completed.