Cocaine-related Disorders
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: Effectiveness of N-acetylcysteine in Treating Cocaine Dependent Individuals - 1 [Phase 1]
This update reports on a Phase 1 trial evaluating the effectiveness of N-acetylcysteine for cocaine-related disorders, sponsored by the Nati…
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: Assessment of Potential Interactions Between Cocaine and RPR 102681 - 1 [Phase 1]
This clinical trial update reports on a Phase 1 study by NIDA to assess potential interactions between cocaine and the experimental compound…
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: Assessment of Potential Interactions Between Intravenous Cocaine and Atomoxetine - 1 [Phase 1]
Phase 1 clinical trial update evaluating potential interactions between intravenous cocaine and atomoxetine in individuals with cocaine-rela…
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: Cocaine Abuse and Attention Deficit Disorder - 3 [NA]
A National Institute on Drug Abuse–sponsored clinical trial focusing on cocaine-related disorders, including cocaine abuse and attention def…
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: Therapeutic Potential of Kappa-Opioids Against Cocaine - 1
This update reports a completed clinical trial evaluating the therapeutic potential of kappa-opioid compounds for cocaine-related disorders.…
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: Interaction Between Vanoxerine (GBR 12909) and Cocaine in Cocaine Dependent Individuals [Phase 1]
This Phase 1 study assessed the interaction between vanoxerine (GBR 12909) and cocaine in cocaine-dependent individuals and was terminated.
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: Psychostimulant Abuse - Novel Treatment Approaches - 1 [Phase 1]
Phase 1 clinical trial update on novel psychostimulant treatments for cocaine-related disorders; the study has completed.
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: Dextroamphetamine as Adjunct in Cocaine/Opiate Dependent Patients - 3 [Phase 2]
Phase 2 clinical trial evaluating dextroamphetamine as an adjunct for cocaine- and opioid-dependent patients has completed.
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: Predictive Values of Serotonergic Alterations for Outcome - 2 [Phase 1]
Phase 1 study evaluating whether serotonergic alterations predict outcomes in cocaine-related disorders was terminated.
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: Acute Withdrawal From Smoked Cocaine - 9 [Phase 1]
The entry notes the completion of a Phase 1 study on acute withdrawal from smoked cocaine conducted by the National Institute on Drug Abuse …
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: Fluoxetine to Reduce Cocaine Use in Cocaine and Opioid Addicts [NA]
Clinical trial investigated fluoxetine to reduce cocaine use in individuals with cocaine- and opioid-use disorders; the study status is comp…
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CLINICAL_TRIALS withdrawal · 2017-01-12Clinical Trial Update: Pemoline in the Treatment of Stimulant Dependence - 5 [Phase 2]
A Phase 2 clinical trial evaluating pemoline for cocaine-related disorders was withdrawn (sponsor: National Institute on Drug Abuse).
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CLINICAL_TRIALS research · 2017-01-11Clinical Trial Update: Evaluation of Modafinil as a Cocaine Treatment Medication and Interactions With Cocaine - 1 [Phase 1]
This clinical trial update describes a Phase 1 study evaluating modafinil as a treatment for cocaine-related disorders and its interactions …
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CLINICAL_TRIALS trial_result · 2017-01-11Clinical Trial Update: Interactions Between Intravenous (IV) Cocaine and Lofexidine [Phase 1]
Phase 1 study evaluating interactions between intravenous cocaine and lofexidine has been terminated.
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CLINICAL_TRIALS trial_result · 2017-01-11Clinical Trial Update: Infusion Laboratory: Protocol 3 (Risperidone) - 4 [Phase 1]
Phase 1 trial update on Risperidone (Infusion Laboratory Protocol 3) for cocaine-related disorders, sponsored by the National Institute on D…
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CLINICAL_TRIALS research · 2017-01-11Clinical Trial Update: Infusion Laboratory: Protocol 2 (Lisuride) - 3 [Phase 1]
A Phase 1 clinical trial update for Lisuride infusion (Protocol 2, update 3) investigating treatment for Cocaine-Related Disorders, sponsore…
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CLINICAL_TRIALS research · 2017-01-11Clinical Trial Update: Drug Interaction Study With NS2359 and Cocaine in Cocaine Experienced Volunteers - 1 [Phase 1]
A Phase 1 drug interaction trial evaluating NS2359 with cocaine in cocaine-experienced volunteers.
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CLINICAL_TRIALS trial_result · 2017-01-11Clinical Trial Update: Assessment of Potential Interactions Between GBR 12909 and Cocaine - 1 [Phase 1]
Phase 1 clinical trial assessing potential interactions between GBR-12909 and cocaine in individuals with cocaine-related disorders; status …
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CLINICAL_TRIALS research · 2017-01-11Clinical Trial Update: GBR 12909 Study in Cocaine Experienced African American Volunteers - 1 [Phase 1]
Phase 1 clinical trial update of GBR-12909 for cocaine-related disorders in cocaine-experienced African American volunteers. Sponsor: Nation…
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CLINICAL_TRIALS trial_result · 2017-01-11Clinical Trial Update: Cocaine-Metyrapone Interaction Study - 1 [Phase 1]
An update on a Phase 1 trial sponsored by NIDA evaluating the interaction between cocaine and metyrapone in cocaine-related disorders (intra…
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CLINICAL_TRIALS research · 2017-01-11Clinical Trial Update: Assessment of the Potential Interactions Between Cocaine and GBR 12909 - 1 [Phase 1]
Phase 1 clinical trial assessing potential interactions between cocaine and GBR-12909 (vanoxerine). Sponsored by the National Institute on D…
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CLINICAL_TRIALS research · 2017-01-11Clinical Trial Update: Development of Human Laboratory Study Model of Cocaine Relapse Prevention. - 1 [Phase 1]
Phase 1 study developing a human laboratory model to study cocaine relapse prevention, sponsored by the National Institute on Drug Abuse.
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CLINICAL_TRIALS research · 2017-01-11Clinical Trial Update: Assessment of Potential Interactions Between Cocaine and Tolcapone - 1 [Phase 1]
An early-phase study funded by NIDA to assess potential interactions between cocaine and the COMT inhibitor tolcapone.
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CLINICAL_TRIALS research · 2017-01-11Clinical Trial Update: Infusion Laboratory: Protocol 5 (Flupenthixol) - 14 [Phase 1]
Phase 1 clinical trial update for Infusion Laboratory: Protocol 5 using flupenthixol in cocaine-related disorders; status is unknown.
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CLINICAL_TRIALS trial_result · 2016-12-16Clinical Trial Update: The Therapeutic Workplace Initiation Study [NA]
Clinical trial update for The Therapeutic Workplace Initiation Study completed; results posted in 2016. Conditions include cocaine-related d…