Coagulopathy
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CLINICAL_TRIALS trial_result · 2026-04-22Clinical Trial Update: Freeze-dried Plasma in the Initial Management of Coagulopathy in Trauma Patients [Phase 3]
A Phase 3 trial evaluating freeze-dried plasma for initial management of coagulopathy in trauma patients has completed.
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: ROTEM Interpretation AI vs Experts
A clinical trial update examining AI-assisted ROTEM interpretation versus expert interpretation for coagulopathy in thromboelastography; the…
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CLINICAL_TRIALS trial_result · 2026-02-11Clinical Trial Update: Microcirculation and Coagulopathy in Sepsis
This entry notes the completion of a clinical trial conducted by Università Politecnica delle Marche. It investigated microcirculation and c…
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CLINICAL_TRIALS research · 2025-10-31Clinical Trial Update: Validation of Point-of-care Thromboelastography (TEG 6s) in Pediatric Patients [NA]
Clinical trial update on a validation study of point-of-care thromboelastography using TEG 6s in pediatric patients with coagulopathy; the s…
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CLINICAL_TRIALS research · 2025-10-09Clinical Trial Update: Phase IIb Multicenter Randomized Controlled Trial Evaluating the Efficacy of Sivelestat in Patients With Septic Coagulopathy [Phase 2]
This Phase IIb multicenter randomized controlled trial is evaluating the efficacy of Sivelestat in patients with septic coagulopathy and is …
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CLINICAL_TRIALS trial_result · 2025-09-18Clinical Trial Update: Ascending Dose Study of FrontlineODP™ Spray Dried Plasma [Phase 1]
This document reports the completion of a Phase 1 ascending-dose trial of FrontlineODP Spray Dried Plasma by Velico Medical. The trial studi…
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CLINICAL_TRIALS research · 2025-09-10Clinical Trial Update: Comparative Study of Tranexamic Acid Dosing in Cardiac Surgery [NA]
ClinicalTrials.gov entry for a comparative dosing study of tranexamic acid in cardiac surgery, currently recruiting to evaluate effects on p…
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CLINICAL_TRIALS research · 2025-07-18Clinical Trial Update: Assessment of Artificial Intelligence Algorithms for ROTEM
A recruiting clinical study at Ondokuz Mayıs University evaluating artificial intelligence algorithms to interpret ROTEM coagulation tests i…
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CLINICAL_TRIALS research · 2025-07-02Clinical Trial Update: Predictive Accuracy of PLR and PNR in Detecting ETIC
This clinical trial update describes a study evaluating how accurately PLR and PNR predict ETIC in trauma-related coagulopathy. The study is…
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CLINICAL_TRIALS trial_result · 2025-05-18Clinical Trial Update: Effects of Gender-Affirming Hormone Therapy Among Transgender Women
A completed clinical trial from Massachusetts General Hospital evaluates gender-affirming hormone therapy in transgender women, examining ef…
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CLINICAL_TRIALS trial_result · 2025-05-13Clinical Trial Update: Quantra vs TEG for Congenital Cardiac Surgery - a Pilot Validation Study
A completed pilot validation study comparing Quantra and TEG for coagulation assessment in congenital cardiac surgery. The study evaluates t…
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CLINICAL_TRIALS trial_result · 2025-04-27Clinical Trial Update: Evaluation of Novel Point of Care Coagulation System in Pregnant Women
A completed clinical trial evaluated a novel point-of-care coagulation system in pregnant women, and results have been posted.
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CLINICAL_TRIALS trial_result · 2025-03-27Clinical Trial Update: Transfusion Using Stored Whole Blood
The UCLA-led clinical trial evaluating transfusion with stored whole blood has completed. It targeted trauma, hemorrhage and coagulopathy.
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CLINICAL_TRIALS trial_result · 2025-03-24Clinical Trial Update: Impact of Renal Replacement Therapy on Coagulation Profile of Patients with Acute Renal Failure
A completed clinical trial evaluated the impact of renal replacement therapy on the coagulation profile of patients with acute renal failure…
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CLINICAL_TRIALS research · 2025-03-17Clinical Trial Update: Thromboelastography to Study Burn Coagulopathy [NA]
This clinical trial registry entry describes a study using thromboelastography to investigate burn-related coagulopathy. The study status is…
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CLINICAL_TRIALS research · 2025-03-14Clinical Trial Update: Patient Blood Management Implementation in CEE Study
This clinical trial update indicates that Semmelweis University is recruiting for the Patient Blood Management Implementation in Central and…
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CLINICAL_TRIALS research · 2025-03-13Clinical Trial Update: Quantra Point-of-Care Hemostasis Monitoring [NA]
A Quantra point-of-care hemostasis monitoring trial at the Cleveland Clinic is currently recruiting for conditions related to bleeding and h…
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CLINICAL_TRIALS trial_result · 2025-03-12Clinical Trial Update: Evaluation of TEG 6S PM® During Cardiopulmonary Bypass to Detect Postoperative Biological Coagulopathy
A completed clinical trial evaluated the TEG 6S PM device during cardiopulmonary bypass to detect postoperative coagulopathy.
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CLINICAL_TRIALS trial_result · 2025-03-06Clinical Trial Update: Clinical Decision Support for Blood Transfusions to Improve Guideline Adherence [NA]
Completed trial evaluating a clinical decision support tool to guide blood transfusions and improve adherence to transfusion guidelines. The…
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CLINICAL_TRIALS research · 2025-02-25Clinical Trial Update: ROTEM Assessment of Modern Crystalloid, Hydroxyethyl Starch and Gelatin Effect on Coagulation
A completed clinical trial assessed how crystalloids, hydroxyethyl starch, and gelatin influence coagulation using ROTEM testing.
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CLINICAL_TRIALS research · 2024-12-18Clinical Trial Update: Goal-directed vs. Empirical Tranexamic Acid Administrationin Cardiovascular Surgery [NA]
A clinical trial update reports ongoing recruitment for comparing goal-directed versus empirical tranexamic acid use in cardiovascular surge…
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CLINICAL_TRIALS trial_result · 2024-11-12Clinical Trial Update: Comparison Between Colloids and Crystalloids on Coagulation and Blood Loss
This clinical trial update reports on a completed study comparing colloids and crystalloids and their effects on coagulation and blood loss …
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: FFP Usage in Pediatric CV Surgery
A completed clinical trial evaluating the use of fresh frozen plasma in pediatric patients undergoing cardiovascular surgery for congenital …
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CLINICAL_TRIALS trial_result · 2024-05-22Clinical Trial Update: Comparison of Viscoelastic Measurement by ROTEM® Delta and ClotPro® in Trauma Patients.
This completed clinical trial evaluated the agreement between viscoelastic measurements using ROTEM Delta and ClotPro in trauma patients to …
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FDA approval · 2023-07-28FDA Approved: PHYTONADIONE — Original Application (Cipla USA., Inc.)
The FDA approved Cipla USA, Inc.'s phytonadione (vitamin K1) under an original application, establishing a generic option for vitamin K supp…