Cluster Headache
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CLINICAL_TRIALS research · 2025-01-27Clinical Trial Update: SPG Pulsed Radiofrequency for Chronic Cluster Headache [NA]
This entry reports that a clinical trial evaluating SPG pulsed radiofrequency for chronic cluster headache is currently recruiting. The stud…
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CLINICAL_TRIALS trial_result · 2024-12-05Clinical Trial Update: Treatment of Chronic Cluster Headache with TENS and ONS [NA]
This clinical trial update reports the completed study evaluating treatment of chronic cluster headache using transcutaneous electrical nerv…
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CLINICAL_TRIALS research · 2024-11-19Clinical Trial Update: Botulinum Toxin Type A Blockade of the Sphenopalatine Ganglion in Treatment-refractory Chronic Cluster Headache [Phase 3]
Phase 3 clinical trial evaluating botulinum toxin type A blockade of the sphenopalatine ganglion for treatment-refractory chronic cluster he…
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CLINICAL_TRIALS trial_result · 2024-08-09Clinical Trial Update: Eptinezumab in Participants With Episodic Cluster Headache [Phase 3]
Phase 3 trial results for eptinezumab in episodic cluster headache have been completed and results posted.
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CLINICAL_TRIALS trial_result · 2024-08-06Clinical Trial Update: A 1-year Trial to Inform About Long-term Exposure to Eptinezumab in Participants With Chronic Cluster Headache (cCH) [Phase 3]
This clinical trial update reports results from a 1-year study assessing long-term exposure to eptinezumab in adults with chronic cluster he…
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CLINICAL_TRIALS research · 2024-07-16Clinical Trial Update: Role of Specific microRNAs in Cluster Headache
A clinical trial is investigating the role of specific microRNAs in cluster headaches and is currently recruiting at the IRCCS National Neur…
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CLINICAL_TRIALS research · 2024-06-26Clinical Trial Update: Bilateral Occipital Nerve Field Stimulation for the Treatment of dtCCH [NA]
This clinical trial update reports that the bilateral occipital nerve field stimulation trial for chronic cluster headache is suspended.
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CLINICAL_TRIALS research · 2024-05-16Clinical Trial Update: An Open Internet-based Survey and Natural Language Processing Project Analysing Written Monologues by Headache Patients
A completed clinical trial update describing an internet-based survey and NLP analysis project that collects and analyzes written monologues…
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CLINICAL_TRIALS trial_result · 2024-05-13Clinical Trial Update: Risk Taking and Decision-making in Cluster Headache Patients
A completed clinical trial evaluating risk-taking and decision-making in patients with cluster headache.
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CLINICAL_TRIALS trial_result · 2024-01-23Clinical Trial Update: Efficacy of Erenumab in Chronic Cluster Headache [Phase 2]
Phase 2 trial update evaluating efficacy of erenumab in chronic cluster headache has completed.
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CLINICAL_TRIALS trial_result · 2022-05-02Clinical Trial Update: Double-Blind Comparison of the Efficacy and Safety of C213 to Placebo for the Acute Treatment of Cluster Headaches [Phase 2, Phase 3]
Clinical trial update reporting a double-blind comparison of C213 to placebo for acute treatment of cluster headaches across Phase 2 and Pha…
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CLINICAL_TRIALS trial_result · 2022-02-10Clinical Trial Update: A Study of LY2951742 (Galcanezumab) in Participants With Cluster Headache [Phase 3]
Phase 3 trial of galcanezumab (LY2951742) in episodic and chronic cluster headache completed; results posted in 2022.
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CLINICAL_TRIALS research · 2021-06-23Clinical Trial Update: Botulinum Toxin Type A Block of the Otic Ganglion in Chronic Cluster Headache: Safety Issues [Phase 1, Phase 2]
A Phase 1/2 trial evaluating safety of botulinum toxin type A injection blocking the otic ganglion for chronic cluster headache; study compl…
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CLINICAL_TRIALS trial_result · 2021-02-24Clinical Trial Update: Effect of Ketamine Intranasal Spray in Treatment of Chronic Cluster Headache [Phase 1, Phase 2]
A completed Phase 1/Phase 2 clinical trial evaluating intranasal ketamine for chronic cluster headache.
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CLINICAL_TRIALS trial_result · 2020-05-06Clinical Trial Update: A Study to Explore the Long-Term Safety and Efficacy of Fremanezumab (TEV-48125) for the Prevention of Cluster Headache [Phase 3]
Phase 3 trial update for fremanezumab in preventing cluster headache; study terminated with posted results in 2020.
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CLINICAL_TRIALS trial_result · 2020-02-28Clinical Trial Update: Occipital Nerve Stimulation in Medically Intractable Chronic Cluster Headache [Phase 3]
Phase 3 clinical trial update for occipital nerve stimulation in medically intractable chronic cluster headache; study completed.
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CLINICAL_TRIALS trial_result · 2020-01-13Clinical Trial Update: Safety and Efficacy Study of SOM230 s.c. in Cluster Headache [Phase 2]
Phase 2 safety and efficacy study of SOM230 s.c. in cluster headache was terminated with results posted.
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CLINICAL_TRIALS trial_result · 2019-09-18Clinical Trial Update: A Study Comparing the Efficacy and Safety of Fremanezumab (TEV-48125) for the Prevention of Chronic Cluster Headache (CCH) [Phase 3]
Phase 3 trial investigating fremanezumab for prevention of chronic cluster headache was terminated; results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-06-11Clinical Trial Update: A Study of Galcanezumab in Participants With Chronic Cluster Headache [Phase 3]
Phase 3 clinical trial update for galcanezumab in chronic cluster headache completed with results posted in 2019.
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FDA approval · 2019-06-04FDA Approved: EMGALITY — Supplemental Application (Eli Lilly and Company)
FDA approved a supplemental application for EMGALITY (galcanezumab) by Eli Lilly and Company. The approval covers a change to the product's …
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CLINICAL_TRIALS trial_result · 2019-04-12Clinical Trial Update: A Pilot Study of Demand Valve Oxygen Inhalation Therapy for Cluster Headache [Phase 1]
Pilot Phase 1 trial of demand valve oxygen inhalation therapy for cluster headache was terminated; results posted.
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CLINICAL_TRIALS trial_result · 2019-02-26Clinical Trial Update: A Randomized Multicentre Study for the Acute Relief of Episodic and Chronic Cluster Headache. [NA]
A randomized multicenter study evaluating acute relief in episodic and chronic cluster headache has completed, with results posted in 2019.
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CLINICAL_TRIALS research · 2019-01-23Clinical Trial Update: PACAP-38 Infusion in Patients With Cluster Headache [NA]
A clinical trial update for PACAP-38 infusion in cluster headache patients; the trial status is currently unknown.
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CLINICAL_TRIALS trial_result · 2018-06-26Clinical Trial Update: Data Collection on the ATI Neurostimulation System: SPG Stimulation for Cluster Headache
This completed clinical trial update describes data collection on the ATI Neurostimulation System using SPG stimulation for cluster headache…
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CLINICAL_TRIALS trial_result · 2018-06-26Clinical Trial Update: Sphenopalatine Ganglion Stimulation for the Treatment of Chronic Cluster Headache [NA]
This is a clinical trial update for Sphenopalatine Ganglion Stimulation as a treatment for Chronic Cluster Headache; the current status and …