Clostridioides Difficile Infection
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2016-06-10Clinical Trial Update: Efficacy of Metronidazole Prophylaxis Against Clostridium Difficile-Associated Diarrhea in High Risk Adult Patients [Phase 4]
This Phase 4 trial evaluated metronidazole as prophylaxis to prevent Clostridioides difficile infection in high-risk adults; the study was t…
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CLINICAL_TRIALS trial_result · 2016-05-03Clinical Trial Update: Efficacy of Loperamide for C. Difficile Colitis and Other Diarrheal Diseases Associated With Antibiotic Therapy [Phase 4]
Phase 4 clinical trial evaluating the efficacy of loperamide for Clostridioides difficile infection and antibiotic-associated diarrhea; the …
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CLINICAL_TRIALS trial_result · 2016-04-21Clinical Trial Update: The Risk for Clostridium Difficile Colitis During Hospitalization in Asymptomatic Carriers
A completed clinical trial evaluated the risk of Clostridioides difficile infection–associated colitis during hospitalization in asymptomati…
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CLINICAL_TRIALS trial_result · 2016-02-23Clinical Trial Update: Molecular Epidemiology of Clostridium Difficile Infections in Children
A completed pediatric study examining the molecular epidemiology of Clostridioides difficile infections, with results posted in 2016.
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CLINICAL_TRIALS trial_result · 2016-01-27Clinical Trial Update: Probiotic Intervention With Elderly Subjects [Phase 2]
Phase 2 clinical trial update on a probiotic intervention in elderly subjects with Clostridioides difficile infection; the study has complet…
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CLINICAL_TRIALS trial_result · 2016-01-15Clinical Trial Update: BIO-K+ CL1285 for Prevention of Recurrent Clostridium Difficile Infection [Phase 3]
A Phase 3 trial evaluating BIO-K+ CL1285 for prevention of recurrent Clostridioides difficile infection has been suspended, with no results …
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CLINICAL_TRIALS trial_result · 2015-12-09Clinical Trial Update: Mucosal Versus Fecal Microbiota in FMT
A completed clinical trial comparing mucosal versus fecal microbiota approaches in fecal microbiota transplantation for Clostridioides diffi…
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CLINICAL_TRIALS trial_result · 2015-12-03Clinical Trial Update: Probiotics for Clostridium Difficile Infection in Older Adults [Phase 2]
This update reports the completion of a Phase 2 clinical trial evaluating probiotics for Clostridioides difficile infection in older adults.
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CLINICAL_TRIALS trial_result · 2015-06-03Clinical Trial Update: Vancomycin vs. Nitazoxanide to Treat Recurrent C. Difficile Colitis
A completed clinical trial compared vancomycin with nitazoxanide for recurrent Clostridioides difficile infection (C. difficile colitis).
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CLINICAL_TRIALS trial_result · 2015-05-05Clinical Trial Update: Study of Nitazoxanide in the Treatment of Clostridium Difficile-associated Disease [Phase 3]
Phase 3 study of nitazoxanide for the treatment of Clostridioides difficile infection has been terminated.
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CLINICAL_TRIALS trial_result · 2015-05-01Clinical Trial Update: Optimal Surgical Treatment Of Fulminant Clostridium Difficile Colitis [NA]
This clinical trial update reports the termination of a study evaluating optimal surgical treatment for fulminant Clostridioides difficile i…
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CLINICAL_TRIALS trial_result · 2015-03-19Clinical Trial Update: A Study of the Absorption of GT267-004 in Patients With Clostridium Difficile-Associated Diarrhea [Phase 2]
A Phase 2 study evaluating the absorption of GT267-004 in patients with Clostridioides difficile infection-associated diarrhea has completed…
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CLINICAL_TRIALS trial_result · 2015-03-19Clinical Trial Update: A Study to Assess the Safety, Tolerability, Effectiveness and Absorption of Exodif™ Tablets in Clostridium Difficile-associated Diarrhea [Phase 3]
Phase 3 trial of Exodif for Clostridioides difficile infection-associated diarrhea was terminated.
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CLINICAL_TRIALS trial_result · 2015-03-05Clinical Trial Update: A Study of GT160-246 Versus Vancomycin in Patients With Clostridium Difficile-Associated Diarrhea [Phase 2]
Phase 2 trial comparing GT160-246 to vancomycin in patients with Clostridioides difficile infection has completed.
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CLINICAL_TRIALS trial_result · 2015-03-05Clinical Trial Update: A Study of GT267-004 Versus Vancomycin and GT267-004 Versus Metronidazole in Patients With C.Difficile - Associated Diarrhea [Phase 3]
Phase 3 study comparing GT267-004 to vancomycin and to metronidazole in patients with Clostridioides difficile infection (C. difficile-assoc…
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CLINICAL_TRIALS trial_result · 2015-03-04Clinical Trial Update: To Determine the Feasibility of a Fidaxomicin Study in Neonates and to Assess C. Difficile (Clostridium Difficile) Involvement in the Pathogenesis
Astellas-sponsored trial evaluating fidaxomicin in neonates to assess Clostridioides difficile involvement has been terminated.
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CLINICAL_TRIALS trial_result · 2015-01-08Clinical Trial Update: Reduction of C-Difficile Infection Using Stool Transplant [Phase 1]
Phase 1 trial investigating fecal microbiota transplantation to reduce Clostridioides difficile infection.
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CLINICAL_TRIALS trial_result · 2014-09-25Clinical Trial Update: An Open-label Study Assessing Safety, Immunogenicity and Dose Response of IC84 [Phase 1]
An open-label Phase 1 study assessing the safety, immunogenicity and dose response of IC84 in Clostridioides difficile infection; the trial …
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CLINICAL_TRIALS trial_result · 2014-08-07Clinical Trial Update: Efficacy and Safety of BIO-K + CL1285 in Prevention of Antibiotic-associated Diarrhea in Hospitalized Adult Patients [Phase 3]
A Phase 3 trial evaluating the efficacy and safety of BIO-K plus CL1285 for preventing antibiotic-associated diarrhea in hospitalized adults…
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CLINICAL_TRIALS trial_result · 2014-06-20Clinical Trial Update: Fecal Microbiota Transplant (FMT) for Relapsing C. Difficile Infection in Adults and Children Using a Frozen Inoculum [Phase 1]
Phase 1 trial evaluating safety and tolerability of a frozen-inoculum fecal microbiota transplant for relapsing Clostridioides difficile inf…
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CLINICAL_TRIALS trial_result · 2014-03-19Clinical Trial Update: A Study of GT267-004 Versus Vancomycin and GT267-004 Versus Metronidazole in Patients With C. Difficile-Associated Diarrhea [Phase 3]
Phase 3 study comparing GT267-004 to vancomycin and metronidazole for Clostridioides difficile infection with associated diarrhea has comple…
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CLINICAL_TRIALS trial_result · 2014-03-06Clinical Trial Update: Evaluation of a 3-dose Vaccination Regimen With One of Three Ascending Dose Levels of Clostridium Difficile Vaccine With or Without Adjuvant in Healthy Adults Aged 50 to 85 Years [Phase 1]
Pfizer conducted a Phase 1 study to evaluate a three-dose vaccination regimen using ascending dose levels of a Clostridioides difficile vacc…
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CLINICAL_TRIALS trial_result · 2014-02-03Clinical Trial Update: Study to Investigate the Pharmacokinetics and Safety of Cadazolid in Patients With Clostridium Difficile Infection [Phase 1]
Phase 1 study evaluating the pharmacokinetics and safety of Cadazolid in patients with Clostridioides difficile infection has completed.
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CLINICAL_TRIALS trial_result · 2013-12-19Clinical Trial Update: Efficacy and Safety of Lactobacillus Acidophilus/Rhamnosus Combination for the Prevention of Antibiotic-associated Diarrhea in the Elderly [Phase 2]
A Phase 2 trial investigating a Lactobacillus acidophilus/Lactobacillus rhamnosus probiotic combination to prevent antibiotic-associated dia…
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CLINICAL_TRIALS trial_result · 2013-10-14Clinical Trial Update: Pharmacokinetics and Safety of Tigecycline in the Treatment of Clostridium Difficile Associated Diarrhea (CDAD) [NA]
A completed clinical trial evaluated the pharmacokinetics and safety of tigecycline for treating Clostridioides difficile infection–associat…