Cleft Palate
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CLINICAL_TRIALS research · 2024-06-27Clinical Trial Update: Velopharyngeal Insufficiency Evaluation Post Cleft Palate Repair. Furlow With Buccinator Myomucosal Flap Versus Two Flap Palatoplasty [NA]
Clinical trial comparing Furlow with Buccinator Myomucosal Flap versus Two Flap Palatoplasty for velopharyngeal insufficiency after cleft pa…
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CLINICAL_TRIALS research · 2024-05-08Clinical Trial Update: Prospective Evaluation of Speech Function Through Patient- and Parent-response Outcome Measurements in Velopharyngeal Insufficiency
This update describes an ongoing prospective study evaluating speech outcomes in children with velopharyngeal insufficiency related to cleft…
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CLINICAL_TRIALS trial_result · 2024-04-30Clinical Trial Update: Furlow With Buccinator and Velopharyngeal Function [NA]
A completed clinical trial from Fayoum University investigating the Furlow double-op technique using the buccinator muscle to improve veloph…
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CLINICAL_TRIALS trial_result · 2024-02-28Clinical Trial Update: Suprazygomatic Maxillary Nerve Block Effect on Systemic Inflammatory Response in Cleft Palate Surgeries [Phase 4]
Phase 4 clinical trial assessing suprazygomatic maxillary nerve block on perioperative inflammatory response and postoperative pain in cleft…
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CLINICAL_TRIALS trial_result · 2023-06-23Clinical Trial Update: Exercises for Improving Soft Palate and Eustachian Tube Function in Children With Ear Tubes With or Without Cleft Palate [NA]
A terminated clinical trial investigating exercises to improve soft palate and Eustachian tube function in children with ear tubes, with or …
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CLINICAL_TRIALS withdrawal · 2022-05-20Clinical Trial Update: The Use of Fibrin Sealant to Reduce Post Operative Pain in Cleft Palate Surgery [Phase 4]
A Phase 4 trial evaluating fibrin sealant to reduce postoperative pain in cleft palate surgery has been withdrawn.
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CLINICAL_TRIALS research · 2019-02-18Clinical Trial Update: Middle Ear Pressure Disregulation in Cleft Palate Patients
The University of Pittsburgh-led clinical trial evaluating middle ear pressure disregulation in cleft palate patients has completed.
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CLINICAL_TRIALS research · 2019-02-12Clinical Trial Update: Bone-borne Palatal Expander With Corticotomy for Cleft Palate Patients [NA]
This entry notes an ongoing clinical trial evaluating a bone-borne palatal expander with corticotomy for cleft palate patients; the study st…
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CLINICAL_TRIALS withdrawal · 2019-02-05Clinical Trial Update: Dexmedetomidine vs Placebo for Pediatric Cleft Palate Repair [Phase 4]
A Phase 4 trial comparing dexmedetomidine to placebo for pediatric cleft palate repair has been withdrawn.
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CLINICAL_TRIALS trial_result · 2018-09-24Clinical Trial Update: Suprazygomatic Block in Cleft Palate Surgery in Children [Phase 2]
Phase 2 clinical trial update for Suprazygomatic Block in cleft palate surgery in children has completed recruitment.
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CLINICAL_TRIALS research · 2018-05-04Clinical Trial Update: FaceBase Biorepository
The FaceBase Biorepository study (NCT01252264), sponsored by Jeff Murray, focusing on craniofacial abnormalities including cleft lip and cle…
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CLINICAL_TRIALS research · 2018-03-20Clinical Trial Update: Partial Adenoidectomy in Cases of Velopharyngeal Dysfunction
A clinical trial from Assiut University is evaluating partial adenoidectomy as a treatment for velopharyngeal dysfunction, including velopha…
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CLINICAL_TRIALS trial_result · 2018-02-01Clinical Trial Update: Preventing Complications in Cleft Palate Repair With Antibiotics [Phase 2]
Phase 2 trial evaluating the use of antibiotics to prevent complications after cleft palate repair; completed with results posted in 2018.
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CLINICAL_TRIALS trial_result · 2017-10-18Clinical Trial Update: Pilot Study Evaluating Characteristic Closure Patterns of the Normal Velopharyngeal Portal [NA]
This completed pilot clinical trial evaluated the characteristic closure patterns of the velopharyngeal portal in individuals with cleft pal…
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CLINICAL_TRIALS research · 2017-09-07Clinical Trial Update: Comparative Study Between Levobupivacaine and Bupivacaine for Nerve Block During Pediatric Primary Cleft Palate Surgery [Phase 2, Phase 3]
A comparative clinical trial evaluating levobupivacaine versus bupivacaine for nerve block in pediatric primary cleft palate surgery; phases…
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CLINICAL_TRIALS trial_result · 2017-06-20Clinical Trial Update: Retrospective Study on the Outcome of Cleft Palate Repair: Comparing US Surgical and Ethicon Suture Materials
A retrospective study evaluating outcomes of cleft palate repair when using US Surgical sutures compared with Ethicon sutures.
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CLINICAL_TRIALS trial_result · 2017-06-16Clinical Trial Update: Acellular Dermal Matrix in Primary Palatoplasty
This clinical trial update reports the completion and results posting of a study evaluating acellular dermal matrix in primary palatoplasty …
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CLINICAL_TRIALS trial_result · 2017-05-31Clinical Trial Update: Using of Acellular Dermal Matrix in Cleft Palatal Fistula and Compare With Use of Conchal Cartolage
A completed clinical trial comparing acellular dermal matrix versus conchal cartilage for the treatment of a cleft palatal fistula.
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CLINICAL_TRIALS trial_result · 2017-05-04Clinical Trial Update: Cell Therapy for Craniofacial Bone Defects [Phase 1, Phase 2]
Phase 1/2 clinical trial update reports results for a cell therapy addressing craniofacial bone defects, including cleft palate, with the st…
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CLINICAL_TRIALS trial_result · 2017-03-31Clinical Trial Update: Oral Cleft Prevention Program [Phase 3]
Phase 3 clinical trial update for the Oral Cleft Prevention Program conducted by the University of Iowa shows the study has completed enroll…
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CLINICAL_TRIALS research · 2017-03-08Clinical Trial Update: Improving Informed Consent for Cleft Palate Repair [NA]
Clinical trial update focusing on improving informed consent for cleft palate repair, with no results or regulatory actions reported.
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CLINICAL_TRIALS research · 2017-02-16Clinical Trial Update: Evaluation of the Incidence of Palatal Fistula in Furlow Double-opposing Z-plasty vs. Two-flap Palatoplasty for Cleft Palate Repair [NA]
A clinical trial evaluating the incidence of palatal fistula after two surgical techniques for cleft palate repair, with current status list…
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CLINICAL_TRIALS trial_result · 2016-12-02Clinical Trial Update: Evaluation of Facial Growth in Two Primary Protocols Used in the Surgical Treatment of Unilateral Cleft Lip and Palate Patients [NA]
An update noting the completion of a clinical trial evaluating two primary surgical protocols for facial growth in patients with unilateral …
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CLINICAL_TRIALS withdrawal · 2016-03-08Clinical Trial Update: IV Acetaminophen in Children Undergoing Palatoplasty [Phase 2]
A Phase 2 clinical trial of intravenous acetaminophen in children undergoing palatoplasty has been withdrawn.
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CLINICAL_TRIALS trial_result · 2016-01-18Clinical Trial Update: Postoperative Complications After Cleft Palate Closure in Patients With Pierre Robin Sequence: Operative Considerations
This clinical trial update reviews potential postoperative complications after cleft palate closure in Pierre Robin sequence and outlines op…