Cirrhosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-12-31Clinical Trial Update: Effect of Whey Protein Versus Egg Albumen Protein Challenge on Blood Ammonia Level in Patients of Decompensated Ethanol Related Cirrhosis. [NA]
A clinical trial comparing whey protein versus egg albumen protein to assess effects on blood ammonia in patients with decompensated ethanol…
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CLINICAL_TRIALS research · 2025-12-31Clinical Trial Update: Impact of Liver Transplantation on Sexual Life and Function
A clinical trial evaluating how liver transplantation affects sexual life and function in patients with chronic liver disease and cirrhosis;…
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CLINICAL_TRIALS research · 2025-12-31Clinical Trial Update: Effect of Acute Endurance Exercise on the Production of FGF21 and Follistatin in Patients With Hepatocellular Carcinoma [NA]
A planned clinical study to evaluate whether acute endurance exercise affects the production of FGF21 and follistatin in patients with hepat…
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CLINICAL_TRIALS withdrawal · 2025-12-24Clinical Trial Update: Rifaximin's Effect on Covert Hepatic Encephalopathy With SIBO and Gastrointestinal Dysmotility [Phase 3]
A Phase 3 trial evaluating rifaximin for covert hepatic encephalopathy with SIBO and GI dysmotility was withdrawn.
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CLINICAL_TRIALS trial_result · 2025-12-22Clinical Trial Update: The Cirrhosis Outpatient Optimization, Readmission & Safety Study [EARLY_Phase 1]
A Phase 1 study on cirrhosis titled Cirrhosis Outpatient Optimization, Readmission & Safety Study (EARLY_Phase 1) has been terminated (NCT02…
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CLINICAL_TRIALS trial_result · 2025-12-19Clinical Trial Update: Interest of the Echocardiography in the Management of Cirrhotic Patients With Acute Kidney Injury [NA]
The trial evaluated the role of echocardiography in the management of cirrhotic patients with hepatorenal syndrome and acute kidney injury. …
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CLINICAL_TRIALS research · 2025-12-19Clinical Trial Update: Effectiveness and Safety of TIPS Stent Graft in the Treatment of Cirrhosis and Complications of Portal Hypertension [NA]
Clinical trial update describing a study evaluating the effectiveness and safety of a TIPS stent graft for portal hypertension due to cirrho…
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: TIPS With or Without BCAA [NA]
A clinical trial evaluating transjugular intrahepatic portosystemic shunt (TIPS) with or without branched-chain amino acids (BCAA) in patien…
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CLINICAL_TRIALS research · 2025-12-12Clinical Trial Update: Microplastics, Cirrhosis and Portal Hypertension
The clinical trial related to cirrhosis and portal hypertension is not yet recruiting and involves microplastics. It notes related condition…
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CLINICAL_TRIALS research · 2025-12-10Clinical Trial Update: Mutational Landscape in Hepatocellular Carcinoma
This clinical trial update summarizes the mutational landscape of hepatocellular carcinoma based on genomic profiling from the completed stu…
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CLINICAL_TRIALS trial_result · 2025-12-01Clinical Trial Update: Repeatability and Reproducibility of Multiparametric MRI
A clinical trial update reports on the repeatability and reproducibility of multiparametric MRI for evaluating liver diseases across several…
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CLINICAL_TRIALS research · 2025-12-01Clinical Trial Update: Novel Tracer Methods to Evaluate Muscle Protein Metabolism in Cirrhosis
An update on an ongoing clinical trial evaluating tracer-based methods to assess muscle protein metabolism in patients with cirrhosis, curre…
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CLINICAL_TRIALS trial_result · 2025-11-26Clinical Trial Update: Study of Semaglutide, and Cilofexor/Firsocostat, Alone and in Combination, in Adults With Cirrhosis Due to Nonalcoholic Steatohepatitis (NASH) [Phase 2]
Phase 2 study evaluating semaglutide alone and in combination with cilofexor and firsocostat for cirrhosis due to nonalcoholic steatohepatit…
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CLINICAL_TRIALS research · 2025-11-25Clinical Trial Update: DEFINITION OF THE GENOMIC LANDSCAPE OF MASLD [NA]
Clinical trial update detailing a study on the genomic landscape of MASLD and cirrhosis; status is recruiting.
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CLINICAL_TRIALS research · 2025-11-25Clinical Trial Update: HMB Enriched Amino Acids to Reverse Muscle Loss in Cirrhosis [NA]
Clinical trial at The Cleveland Clinic is evaluating whether HMB-enriched amino acids can reverse muscle loss in patients with liver cirrhos…
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: Timing of Endoscopic Intervention for Acute Variceal Hemorrhage: an RCT [NA]
This clinical trial update describes an ongoing randomized study evaluating the timing of endoscopic intervention for acute variceal hemorrh…
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CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: A Community-based Prospective Cohort Study on Metabolic Dysfunction-Associated Fatty Liver Disease in Older Adults: From Metabolic Trajectories to Extrahepatic Outcomes
A community-based prospective cohort study is investigating metabolic dysfunction-associated fatty liver disease in older adults to understa…
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CLINICAL_TRIALS trial_result · 2025-11-20Clinical Trial Update: Non Invasive Study of the Hepatic Fibrosis in Paediatrics by the Method of Study of Pediatric Hepatic Fibrosis [NA]
A completed clinical trial update describing a non-invasive approach to assess hepatic fibrosis in pediatric patients. The document notes th…
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: Screening Cardiometabolic Opportunities Using Transformative Echocardiography Artificial Intelligence (SCOUT Echo-AI) [NA]
A clinical trial update for SCOUT Echo-AI, a screening study using echocardiography AI to explore cardiometabolic opportunities in MASLD and…
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EMA approval · 2025-11-10EMA Authorised: Rezdiffra (resmetirom) — Madrigal Pharmaceuticals EU Limited
EMA authorised Rezdiffra (resmetirom) for non-alcoholic fatty liver disease and cirrhosis of the liver, granted with conditional approval.
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CLINICAL_TRIALS research · 2025-10-30Clinical Trial Update: Bumetanide vs. Furosemide in Cirrhosis [Phase 3]
A Phase 3 clinical trial comparing bumetanide with furosemide in adults with cirrhosis. The study is currently not yet recruiting.
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CLINICAL_TRIALS trial_result · 2025-10-15Clinical Trial Update: ALTUS: Performance of a Multi- Target Hepatocellular Carcinoma (HCC) Test in Subjects With Increased Risk
Exact Sciences is reporting on the performance of a multi-target hepatocellular carcinoma test in individuals at increased risk. The clinica…
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CLINICAL_TRIALS trial_result · 2025-10-15Clinical Trial Update: EDUCATE-C: Education on Cirrhosis -- Assessing Text vs Video [NA]
The EDUCATE-C trial evaluating text versus video education for cirrhosis has completed.
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CLINICAL_TRIALS research · 2025-10-07Clinical Trial Update: Validation of CAGIB Score for In-hospital Mortality of Cirrhotic Patients With Acute Gastrointestinal Bleeding
This clinical trial aims to validate the CAGIB score for predicting in-hospital mortality in cirrhotic patients with acute gastrointestinal …
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CLINICAL_TRIALS research · 2025-09-30Clinical Trial Update: A Prospective Study of Memantine in Patients With Cirrhosis and Liver Cancer [Phase 2, Phase 3]
A prospective Phase 2/Phase 3 clinical trial evaluating memantine in patients with cirrhosis and hepatocellular carcinoma is currently recru…