Cirrhosis
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CLINICAL_TRIALS trial_result · 2009-02-05Clinical Trial Update: Brain Energy Metabolism in Patients With Chronic Liver Disease and Impaired Central Nervous System
The document reports the completed results of a clinical trial evaluating brain energy metabolism in patients with chronic liver disease and…
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CLINICAL_TRIALS research · 2009-01-12Clinical Trial Update: Endoscopic Sclerotherapy and/or Ligation Versus Portacaval Shunt for Bleeding Gastric Varices [NA]
This clinical trial update reports completion of a study comparing endoscopic sclerotherapy and/or ligation with portacaval shunt for bleedi…
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CLINICAL_TRIALS trial_result · 2009-01-09Clinical Trial Update: Transjugular Intrahepatic Portosystemic Shunt With 8- or 10-mm Covered Stents [Phase 2]
Phase 2 trial evaluating transjugular intrahepatic portosystemic shunt with 8- or 10-mm covered stents in cirrhosis has been terminated.
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CLINICAL_TRIALS trial_result · 2008-11-25Clinical Trial Update: Effect of Pioglitazone on Portal and Systemic Hemodynamics in Patients With Advanced Cirrhosis [Phase 4]
A Phase 4 trial evaluated the effects of pioglitazone on portal and systemic hemodynamics in patients with advanced cirrhosis; the study has…
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CLINICAL_TRIALS other · 2008-10-15Clinical Trial Update: Acute Hemodynamics of Albumin Versus Normal Saline in Cirrhosis [NA]
A clinical trial comparing albumin to normal saline in patients with cirrhosis and ascites has been suspended.
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CLINICAL_TRIALS trial_result · 2008-09-25Clinical Trial Update: Spironolactone Versus Spironolactone Plus Furosemide (SVSSF) [Phase 4]
This ClinicalTrials.gov update reports a Phase 4 trial comparing spironolactone alone versus spironolactone plus furosemide in patients with…
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FDA approval · 2008-08-15FDA Approved: HYDROCHLOROTHIAZIDE — Original Application (Exelan Pharmaceuticals Inc.)
The FDA approved Exelan Pharmaceuticals Inc.'s original application for hydrochlorothiazide, a generic diuretic indicated for hypertension a…
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CLINICAL_TRIALS trial_result · 2008-08-07Clinical Trial Update: Effect of Meal on Portal and Esophagus Variceal Pressure [NA]
A clinical trial evaluating the effect of meal on portal and esophageal variceal pressure in patients with cirrhosis and esophageal varices …
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CLINICAL_TRIALS trial_result · 2008-03-06Clinical Trial Update: Prediction of Hepatic Fibrosis in Patients With Chronic Hepatitis C by Biochemical and Duplex Doppler Indices
A completed clinical trial evaluating the ability to predict hepatic fibrosis in chronic hepatitis C patients using biochemical measurements…
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CLINICAL_TRIALS trial_result · 2008-01-17Clinical Trial Update: Sedation and Analgesia for Transjugular Liver Biopsy: A Randomized Double Blind Placebo Controlled Trial [Phase 4]
Phase 4 randomized double-blind placebo-controlled trial evaluating sedation and analgesia during transjugular liver biopsy in patients with…
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CLINICAL_TRIALS trial_result · 2008-01-17Clinical Trial Update: Clinical Trial of Pentoxifylline in Patient With Cirrhosis [Phase 3]
This entry reports that a Phase 3 clinical trial of pentoxifylline in patients with cirrhosis and liver failure has completed.
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CLINICAL_TRIALS trial_result · 2008-01-15Clinical Trial Update: Efficacy and Safety of Simvastatin in the Treatment of Portal Hypertension [Phase 2]
A Phase 2 trial evaluated the efficacy and safety of simvastatin for portal hypertension in cirrhosis and has completed.
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CLINICAL_TRIALS trial_result · 2007-12-05Clinical Trial Update: The Safety & Efficacy of Terlipressin vs Octreotide for the Control of Variceal Bleed [Phase 4]
Phase 4 trial comparing terlipressin to octreotide for control of variceal bleeding in patients with portal hypertension due to cirrhosis; s…
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CLINICAL_TRIALS trial_result · 2007-11-01Clinical Trial Update: Safety and Efficacy Study of Interferon Gamma-1b in Hepatitis C Patients With Liver Fibrosis or Cirrhosis [Phase 2]
A Phase 2 trial assessed the safety and efficacy of Interferon Gamma-1b in hepatitis C patients with liver fibrosis or cirrhosis. The study …
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CLINICAL_TRIALS trial_result · 2007-11-01Clinical Trial Update: Effect of Yogurt on Minimal Hepatic Encephalopathy [NA]
Clinical trial update announcing completion of a study assessing whether yogurt affects minimal hepatic encephalopathy in cirrhosis patients…
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CLINICAL_TRIALS trial_result · 2007-11-01Clinical Trial Update: DOCICAR: Cardiac Dysfunction in Cirrhosis
The DOCICAR trial investigating cardiac dysfunction in cirrhosis has completed. It studied cirrhotic cardiomyopathy associated with cirrhosi…
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CLINICAL_TRIALS trial_result · 2007-08-08Clinical Trial Update: Lyspro Insulin vs Regular Insulin in Cirrhotic Patients [Phase 4]
A Phase 4 clinical trial comparing lyspro insulin with regular insulin in patients with diabetes mellitus and cirrhosis has completed.
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FDA approval · 2007-06-29FDA Approved: FUROSEMIDE — Supplemental Application (Leading Pharma, LLC)
FDA approves a supplemental application for furosemide submitted by Leading Pharma, LLC.
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CLINICAL_TRIALS trial_result · 2007-04-11Clinical Trial Update: Treatment of Hepatorenal Syndrome With Terlipressin Plus Albumin vs Albumin [Phase 4]
A Phase 4 trial evaluating terlipressin plus albumin versus albumin for hepatorenal syndrome has been suspended.
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CLINICAL_TRIALS trial_result · 2007-03-21Clinical Trial Update: Secondary Prophylaxis After Variceal Bleeding in Non-Responders [Phase 4]
Phase 4 trial update on secondary prophylaxis after variceal bleeding in non-responders has completed.
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CLINICAL_TRIALS trial_result · 2006-12-04Clinical Trial Update: The Effects of Clonidine on the Diuretic Response in Cirrhotic Patients [NA]
A completed clinical trial evaluated the effect of clonidine on the diuretic response in patients with ascitic cirrhosis and sympathetic ner…
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CLINICAL_TRIALS trial_result · 2006-08-03Clinical Trial Update: Norfloxacin In The Primary Prophylaxis Of Spontaneous Bacterial Peritonitis [Phase 4]
Phase 4 trial evaluating Norfloxacin for primary prophylaxis of spontaneous bacterial peritonitis has completed. The study includes patients…