Cirrhosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-05-17Clinical Trial Update: The Study of Spectrum of Sleep Disorders in Cirrhotic Patients and the Efficacy of Zolpidem in Cirrhotic Patients With Insomnia [NA]
Completed clinical trial studying sleep disorders in cirrhosis and evaluating zolpidem for insomnia in cirrhotic patients.
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CLINICAL_TRIALS trial_result · 2018-05-11Clinical Trial Update: Rifaximin in Patients With Gastroesophageal Variceal Bleeding [NA]
Clinical trial update notes the completion of a rifaximin study in patients with gastroesophageal variceal bleeding due to cirrhosis.
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CLINICAL_TRIALS trial_result · 2018-04-30Clinical Trial Update: Sofosbuvir, Ledipasvir, Ribavirin for Hepatitis C Cirrhotics, Genotype 1 [Phase 3]
Clinical trial update indicating completion of a Phase 3 study of Sofosbuvir, Ledipasvir, and Ribavirin for genotype 1 hepatitis C in patien…
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CLINICAL_TRIALS research · 2018-04-25Clinical Trial Update: Multicenter Prospective Randomized Trial of the Effect of Rivaroxaban on Survival and Development of Complications of Portal Hypertension in Patients With Cirrhosis [Phase 3]
Phase 3 multicenter randomized trial evaluating rivaroxaban on survival and development of portal hypertension complications in patients wit…
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FDA approval · 2018-04-23FDA Approved: SAMSCA — Supplemental Application (Otsuka America Pharmaceutical, Inc.)
FDA approved a supplemental application for Samsca (tolvaptan) from Otsuka America Pharmaceutical.
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CLINICAL_TRIALS research · 2018-04-11Clinical Trial Update: Efficacity and Safety of Tranexamic Acid in Cirrhotic Patients Presenting With Acute Upper Gastrointestinal Bleeding [Phase 4]
A Phase 4 clinical trial evaluating the efficacy and safety of tranexamic acid in cirrhotic patients with acute upper gastrointestinal bleed…
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CLINICAL_TRIALS trial_result · 2018-04-06Clinical Trial Update: A (M)Ulti-center, Prospective, (O)Pen Label, Uncontrolled Feasibility (S)Tudy to Assess the Safety and Effectiveness of an Automatic Low Flow (A)Scites (Alfa) Pump (I)n Patients With (C)Irrhosis and Refractory or Recurrent Ascites [NA]
This clinical trial update reports the completion of a multicenter, prospective, open-label feasibility study evaluating the safety and effe…
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CLINICAL_TRIALS trial_result · 2018-04-04Clinical Trial Update: Oral Gut Liver Axis in Cirrhosis [NA]
A clinical trial investigating the oral-gut-liver axis in cirrhosis, with concomitant periodontitis and gingivitis, has completed. The updat…
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CLINICAL_TRIALS trial_result · 2018-03-19Clinical Trial Update: Comparison of Terlipressin, Somatostatin, and Octreotide for Control of Variceal Bleeding [Phase 4]
Phase 4 trial comparing terlipressin, somatostatin, and octreotide for control of variceal bleeding in cirrhosis; results have been posted.
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CLINICAL_TRIALS trial_result · 2018-03-19Clinical Trial Update: Proton Pump Inhibitors and Dysbiosis in Cirrhosis [NA]
Completed results from a trial evaluating the effect of proton pump inhibitors on gut dysbiosis in individuals with cirrhosis. The study als…
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CLINICAL_TRIALS withdrawal · 2018-03-13Clinical Trial Update: Effect of Vivomixx® on Neuroinflammation in Patients Withs Cirrhosis [NA]
The clinical trial evaluating Vivomixx for neuroinflammation in patients with cirrhosis has been withdrawn.
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CLINICAL_TRIALS research · 2018-02-28Clinical Trial Update: To Compare Efficacy and Safety of Lactulose Versus Polyethylene Glycol for Treatment of Overt Hepatic Encephalopathy in Cirrhotics. [NA]
A clinical trial update comparing lactulose with polyethylene glycol for overt hepatic encephalopathy in patients with cirrhosis; current st…
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CLINICAL_TRIALS withdrawal · 2018-02-27Clinical Trial Update: Impact on Morbidity and Mortality of Prophylactic Dosing of Low Molecular Heparin in Child-Pugh B Cirrhotic Patients [Phase 3]
Phase 3 trial evaluating prophylactic dosing of low molecular weight heparin in Child-Pugh B cirrhosis patients has been suspended.
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CLINICAL_TRIALS trial_result · 2017-12-28Clinical Trial Update: Albumin Infusion Effects in Mortality in Patients With Cirrhosis and Hepatic Encephalopathy [Phase 4]
Phase 4 trial investigating albumin infusion effects on mortality in patients with cirrhosis and hepatic encephalopathy.
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CLINICAL_TRIALS trial_result · 2017-12-11Clinical Trial Update: Antifibrotic Activity Of GI262570 In Chronic Hepatitis C Subjects [Phase 2]
Phase 2 trial evaluating the antifibrotic agent GI262570 in patients with chronic hepatitis C and liver cirrhosis has completed, with result…
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CLINICAL_TRIALS research · 2017-11-29Clinical Trial Update: On Demand Versus Protocol-guided Renal Replacement Therapy for Management of Stage 3 Acute Kidney Injury in Patients With Cirrhosis [NA]
This clinical trial update discusses comparing on-demand versus protocol-guided renal replacement therapy for stage 3 acute kidney injury in…
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CLINICAL_TRIALS withdrawal · 2017-11-28Clinical Trial Update: To Study and Compare the Clinical Course and Development of Organ Failure in Severe Acute Hepatitis Without Ascites, Non-cirrhotic and Cirrhotic Patients With Ascites [Acute on Chronic Liver Failure] and Acute Deterioration of Previously Decompensated Cirrhosis.
This ClinicalTrials.gov entry indicates that the study evaluating the clinical course and organ failure in severe acute hepatitis with and w…
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CLINICAL_TRIALS trial_result · 2017-11-21Clinical Trial Update: To Determine the Role of Prokinetics in Feed Intolerance in Critically Ill Cirrhosis [NA]
A completed clinical trial update from India evaluating the role of prokinetic agents in feeding intolerance among critically ill patients w…
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CLINICAL_TRIALS trial_result · 2017-11-14Clinical Trial Update: Safety and Efficacy of SOF/VEL/VOX FDC for 8 Weeks and SOF/VEL for 12 Weeks in Adults Chronic Genotype 3 HCV Infection and Cirrhosis [Phase 3]
Phase 3 trial evaluating eight weeks of SOF/VEL/VOX fixed-dose combination or twelve weeks of SOF/VEL in adults with chronic genotype 3 hepa…
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CLINICAL_TRIALS trial_result · 2017-11-08Clinical Trial Update: Correlation of Hepatitis C, Alcoholic Liver Disease, and Renal Failure With Hyperfibrinolysis in Liver Failure
A completed clinical trial examining the relationship between Hepatitis C, alcoholic liver disease, renal failure, and hyperfibrinolysis in …
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CLINICAL_TRIALS research · 2017-11-07Clinical Trial Update: Relationship Between HbA1c and Chronic Glycemia in Patients With Cirrhosis
A completed clinical trial update examining the relationship between HbA1c and chronic glycemia in patients with cirrhosis and Type 2 diabet…
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CLINICAL_TRIALS trial_result · 2017-10-27Clinical Trial Update: FibroScan in Patients With Hepatitis B and C Presenting for Liver Biopsy [NA]
Clinical trial evaluating FibroScan in patients with cirrhosis, hepatitis B, or hepatitis C undergoing liver biopsy has completed and posted…
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CLINICAL_TRIALS trial_result · 2017-10-13Clinical Trial Update: Gabapentin to Treat Itch in Patients With Liver Disease [Phase 3]
This update reports the completion of a Phase 3 trial evaluating gabapentin to treat itch in patients with liver disease.
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CLINICAL_TRIALS trial_result · 2017-09-19Clinical Trial Update: Role of Midodrine and Tolvaptan in Patients With Cirrhosis With Refractory or Recurrent Ascites [Phase 2, Phase 3]
A completed Phase 2/3 clinical trial evaluating the role of midodrine and tolvaptan in patients with cirrhosis and refractory or recurrent a…
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CLINICAL_TRIALS trial_result · 2017-08-30Clinical Trial Update: A Study to Evaluate the Safety and Efficacy of Ombitasvir/Paritaprevir/Ritonavir and Dasabuvir With or Without Ribavirin in US Veterans With Genotype 1 Chronic Hepatitis C Virus Infection [Phase 3]
A Phase 3 trial evaluating the safety and efficacy of the Ombitasvir/Paritaprevir/Ritonavir and Dasabuvir regimen (with or without Ribavirin…