Cirrhosis
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CLINICAL_TRIALS trial_result · 2018-04-30Clinical Trial Update: Sofosbuvir, Ledipasvir, Ribavirin for Hepatitis C Cirrhotics, Genotype 1 [Phase 3]
Clinical trial update indicating completion of a Phase 3 study of Sofosbuvir, Ledipasvir, and Ribavirin for genotype 1 hepatitis C in patien…
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CLINICAL_TRIALS trial_result · 2018-04-06Clinical Trial Update: A (M)Ulti-center, Prospective, (O)Pen Label, Uncontrolled Feasibility (S)Tudy to Assess the Safety and Effectiveness of an Automatic Low Flow (A)Scites (Alfa) Pump (I)n Patients With (C)Irrhosis and Refractory or Recurrent Ascites [NA]
This clinical trial update reports the completion of a multicenter, prospective, open-label feasibility study evaluating the safety and effe…
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CLINICAL_TRIALS trial_result · 2018-04-04Clinical Trial Update: Oral Gut Liver Axis in Cirrhosis [NA]
A clinical trial investigating the oral-gut-liver axis in cirrhosis, with concomitant periodontitis and gingivitis, has completed. The updat…
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CLINICAL_TRIALS trial_result · 2018-03-19Clinical Trial Update: Comparison of Terlipressin, Somatostatin, and Octreotide for Control of Variceal Bleeding [Phase 4]
Phase 4 trial comparing terlipressin, somatostatin, and octreotide for control of variceal bleeding in cirrhosis; results have been posted.
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CLINICAL_TRIALS trial_result · 2018-03-19Clinical Trial Update: Proton Pump Inhibitors and Dysbiosis in Cirrhosis [NA]
Completed results from a trial evaluating the effect of proton pump inhibitors on gut dysbiosis in individuals with cirrhosis. The study als…
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CLINICAL_TRIALS trial_result · 2017-12-28Clinical Trial Update: Albumin Infusion Effects in Mortality in Patients With Cirrhosis and Hepatic Encephalopathy [Phase 4]
Phase 4 trial investigating albumin infusion effects on mortality in patients with cirrhosis and hepatic encephalopathy.
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CLINICAL_TRIALS trial_result · 2017-12-11Clinical Trial Update: Antifibrotic Activity Of GI262570 In Chronic Hepatitis C Subjects [Phase 2]
Phase 2 trial evaluating the antifibrotic agent GI262570 in patients with chronic hepatitis C and liver cirrhosis has completed, with result…
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CLINICAL_TRIALS trial_result · 2017-11-21Clinical Trial Update: To Determine the Role of Prokinetics in Feed Intolerance in Critically Ill Cirrhosis [NA]
A completed clinical trial update from India evaluating the role of prokinetic agents in feeding intolerance among critically ill patients w…
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CLINICAL_TRIALS trial_result · 2017-11-14Clinical Trial Update: Safety and Efficacy of SOF/VEL/VOX FDC for 8 Weeks and SOF/VEL for 12 Weeks in Adults Chronic Genotype 3 HCV Infection and Cirrhosis [Phase 3]
Phase 3 trial evaluating eight weeks of SOF/VEL/VOX fixed-dose combination or twelve weeks of SOF/VEL in adults with chronic genotype 3 hepa…
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CLINICAL_TRIALS trial_result · 2017-11-08Clinical Trial Update: Correlation of Hepatitis C, Alcoholic Liver Disease, and Renal Failure With Hyperfibrinolysis in Liver Failure
A completed clinical trial examining the relationship between Hepatitis C, alcoholic liver disease, renal failure, and hyperfibrinolysis in …
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CLINICAL_TRIALS trial_result · 2017-10-27Clinical Trial Update: FibroScan in Patients With Hepatitis B and C Presenting for Liver Biopsy [NA]
Clinical trial evaluating FibroScan in patients with cirrhosis, hepatitis B, or hepatitis C undergoing liver biopsy has completed and posted…
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CLINICAL_TRIALS trial_result · 2017-10-13Clinical Trial Update: Gabapentin to Treat Itch in Patients With Liver Disease [Phase 3]
This update reports the completion of a Phase 3 trial evaluating gabapentin to treat itch in patients with liver disease.
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CLINICAL_TRIALS trial_result · 2017-09-19Clinical Trial Update: Role of Midodrine and Tolvaptan in Patients With Cirrhosis With Refractory or Recurrent Ascites [Phase 2, Phase 3]
A completed Phase 2/3 clinical trial evaluating the role of midodrine and tolvaptan in patients with cirrhosis and refractory or recurrent a…
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CLINICAL_TRIALS trial_result · 2017-08-30Clinical Trial Update: A Study to Evaluate the Safety and Efficacy of Ombitasvir/Paritaprevir/Ritonavir and Dasabuvir With or Without Ribavirin in US Veterans With Genotype 1 Chronic Hepatitis C Virus Infection [Phase 3]
A Phase 3 trial evaluating the safety and efficacy of the Ombitasvir/Paritaprevir/Ritonavir and Dasabuvir regimen (with or without Ribavirin…
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CLINICAL_TRIALS trial_result · 2017-08-29Clinical Trial Update: Adult-to-Adult Living Donor Liver Transplantation Study
This clinical trial update reports the completion of the Adult-to-Adult Living Donor Liver Transplantation study (NCT00096733), sponsored by…
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CLINICAL_TRIALS trial_result · 2017-08-23Clinical Trial Update: Endoscopic Band Ligation (EBL) Versus Propranolol for Primary Prophylaxis of Variceal Bleeding [Phase 4]
Phase 4 clinical trial evaluating Endoscopic Band Ligation versus Propranolol for primary prevention of variceal bleeding in patients with c…
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CLINICAL_TRIALS trial_result · 2017-08-22Clinical Trial Update: Study on B-blockers to Prevent Decompensation of Cirrhosis With HTPortal [Phase 4]
Phase 4 clinical trial evaluating non-selective beta-blockers to prevent decompensation in cirrhosis with portal hypertension has completed.
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CLINICAL_TRIALS trial_result · 2017-08-22Clinical Trial Update: EBL Versus EBL and Propranolol for the Prevention of Variceal Rebleeding in Pts With Previous Variceal Treatment [Phase 4]
Phase 4 clinical trial comparing endoscopic band ligation (EBL) alone to EBL with propranolol for preventing variceal rebleeding in patients…
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CLINICAL_TRIALS trial_result · 2017-08-22Clinical Trial Update: Early Screening of Hepatocellular Carcinoma in Cirrhotic Patients: a Prospective Study
This document provides an update on a prospective trial evaluating early screening for hepatocellular carcinoma in patients with cirrhosis.
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CLINICAL_TRIALS trial_result · 2017-08-10Clinical Trial Update: Thrombin Generation Test in Patient With Liver Cirrhosis
Clinical trial update on thrombin generation testing in a patient with liver cirrhosis. The study status is completed.
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CLINICAL_TRIALS trial_result · 2017-08-07Clinical Trial Update: Intravenous Interferon During Liver Transplant [NA]
A completed clinical trial investigating intravenous interferon during liver transplant with Hepatitis C and cirrhosis as conditions; result…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Transplant-Related Accelerated Progression of Hepatitis C
A completed clinical trial examining transplant-related accelerated progression of hepatitis C in patients with cirrhosis.
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CLINICAL_TRIALS trial_result · 2017-05-11Clinical Trial Update: Feasibility of Critical Flicker Frequency Procedure for the Diagnosis of Minimal Encephalopathy [NA]
This clinical trial update reports on the feasibility of using the critical flicker frequency procedure to diagnose minimal hepatic encephal…
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CLINICAL_TRIALS trial_result · 2017-05-11Clinical Trial Update: Minimal HePatic Encephalopathy Among CiRrhotics. A Cross SEctional, Clinico-EpidEmiological, Multi-Centre, Study in Patients of PakisTan
A completed cross-sectional, multicenter study in Pakistan evaluating minimal hepatic encephalopathy in patients with cirrhosis.
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CLINICAL_TRIALS trial_result · 2017-05-11Clinical Trial Update: Transient Elastography to Assess Liver Fibrosis and Portal Hypertension in HCV Cirrhotic Patients Treated With New Antiviral Drugs (SPLEEN-C) [NA]
A completed clinical trial (SPLEEN-C) evaluating transient elastography to measure liver fibrosis and portal hypertension in patients with c…