Cirrhosis
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CLINICAL_TRIALS trial_result · 2025-09-24Clinical Trial Update: A Study to Detect Advanced Liver Disease Via AI-enabled Electrocardiogram [NA]
A Mayo Clinic-sponsored trial evaluating an AI-enabled electrocardiogram to detect advanced liver disease has completed. The study targeted …
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CLINICAL_TRIALS trial_result · 2025-09-17Clinical Trial Update: Health IT Generated PROs to Improve Outcomes in Cirrhosis [NA]
A completed clinical trial evaluated health IT-generated patient-reported outcomes to improve outcomes in cirrhosis. Results were posted in …
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CLINICAL_TRIALS trial_result · 2025-09-12Clinical Trial Update: Angiotensin 2 for AKI After OLT [Phase 4]
Phase 4 clinical trial update evaluating Angiotensin II for acute kidney injury following orthotopic liver transplantation; enrollment is by…
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CLINICAL_TRIALS trial_result · 2025-09-02Clinical Trial Update: Volume Resuscitation in Cirrhosis With Sepsis Induced Hypotension
This entry notes the completion of a clinical trial evaluating volume resuscitation in patients with cirrhosis and sepsis-induced hypotensio…
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CLINICAL_TRIALS trial_result · 2025-08-24Clinical Trial Update: Role of Exercise in Chronic Liver Disease Patients Undergoing Liver Transplantation [NA]
A completed clinical trial evaluating the role of exercise in patients with chronic liver disease undergoing liver transplantation.
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CLINICAL_TRIALS trial_result · 2025-08-01Clinical Trial Update: Evaluation of a Nutrition Education Guide for Patients With Cirrhosis [NA]
A completed clinical trial evaluating a nutrition education guide for patients with cirrhosis.
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CLINICAL_TRIALS trial_result · 2025-07-22Clinical Trial Update: A Pilot Trial to Test the Feasibility of Utilizing Home Blood Pressure Monitoring to Optimize the Administration of Midodrine Among Decompensated Cirrhosis Patients [NA]
A pilot trial evaluating the feasibility of using home blood pressure monitoring to optimize midodrine dosing in patients with decompensated…
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CLINICAL_TRIALS trial_result · 2025-07-18Clinical Trial Update: Lung Point of Care Ultrasound to Guide Albumin Administration in Cirrhosis [Phase 3]
A Phase 3 trial evaluating whether point-of-care lung ultrasound can guide albumin administration in cirrhosis has completed.
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CLINICAL_TRIALS trial_result · 2025-07-17Clinical Trial Update: Patient Buddy App for the Prevention of Avoidable Readmission in Cirrhosis
This clinical trial update reports the completion and posting of results for a study evaluating the Patient Buddy App to prevent avoidable r…
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CLINICAL_TRIALS trial_result · 2025-06-24Clinical Trial Update: Allopurinol and Pathogenesis of Cirrhosis [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial evaluating allopurinol for the pathogenesis of cirrhosis has completed. The study was sponsored by Tanta Un…
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CLINICAL_TRIALS trial_result · 2025-06-04Clinical Trial Update: Droxidopa to Increase Mean Arterial Pressure in Decompensated Cirrhosis Patients With Acute Kidney Injury [Phase 2]
A Phase 2 clinical trial is investigating droxidopa to increase mean arterial pressure in patients with decompensated cirrhosis and acute ki…
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CLINICAL_TRIALS trial_result · 2025-05-25Clinical Trial Update: FMT in Cirrhosis and Hepatic Encephalopathy [Phase 1, Phase 2]
This update reports the completed Phase 1 and Phase 2 trials of fecal microbiota transplantation for cirrhosis and hepatic encephalopathy, w…
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CLINICAL_TRIALS trial_result · 2025-05-23Clinical Trial Update: A Study to Evaluate the Pharmacokinetics and Safety of K-808 (Pemafibrate) in Subjects With Primary Biliary Cholangitis With Compensated Cirrhosis and Without Cirrhosis. [Phase 1]
Phase 1 study evaluating the pharmacokinetics and safety of pemafibrate (K-808) in subjects with primary biliary cholangitis with compensate…
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CLINICAL_TRIALS trial_result · 2025-05-16Clinical Trial Update: Composition for Treating Cirrhosis and Liver Cancer (SB-1121) [Phase 4]
Phase 4 clinical trial update indicating completion of SB-1121 for cirrhosis of the liver.
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CLINICAL_TRIALS trial_result · 2025-05-16Clinical Trial Update: Mild Hypothermia and Acute Kidney Injury in Liver Transplantation [NA]
A terminated UCSF-led clinical trial evaluated mild hypothermia for reducing acute kidney injury after liver transplantation, with results p…
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CLINICAL_TRIALS trial_result · 2025-05-15Clinical Trial Update: NEPH-ROSIS (NEPHrology in CirRhOSIS) Pilot Trial: A Trial to Treat Acute Kidney Injury Among Hospitalized Cirrhosis Patients [Phase 2, Phase 3]
NEPH-ROSIS, a Phase 2/3 pilot trial for treating acute kidney injury in hospitalized cirrhosis patients, has been terminated.
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CLINICAL_TRIALS trial_result · 2025-05-09Clinical Trial Update: Compare the Diuretic Effect With Furosemide vs Furosemide and Albumin Combined in Cirrhotic Patients [Phase 4]
Phase 4 trial in cirrhosis comparing the diuretic effect of furosemide alone versus furosemide with albumin; the study was terminated and re…
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CLINICAL_TRIALS trial_result · 2025-04-20Clinical Trial Update: Microbiota Study in Liver Transplanted Patients
A microbiota-focused clinical trial in patients with cirrhosis and hepatocellular carcinoma undergoing liver transplantation has completed.
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CLINICAL_TRIALS trial_result · 2025-04-10Clinical Trial Update: Two Strategies of Primary Prophylaxis of Spontaneous Bacterial Peritonitis in Severe Cirrhotic Patients With Ascites [Phase 3]
A Phase 3 trial comparing two strategies for primary prophylaxis of spontaneous bacterial peritonitis in patients with cirrhosis and ascites…
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CLINICAL_TRIALS trial_result · 2025-04-03Clinical Trial Update: Metobolomics in the Characterisation of HE
The document reports completion of a metabolomics study aimed at characterizing hepatic encephalopathy in patients with cirrhosis.
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CLINICAL_TRIALS trial_result · 2025-03-21Clinical Trial Update: Apixaban, Warfarin and Aspirin Prevents Portal Vein Thrombosis in Patients After Laparoscopic Splenectomy（ESAWAAPT） [Phase 4]
A Phase 4 trial assessed whether apixaban, warfarin, and aspirin can prevent portal vein thrombosis after laparoscopic splenectomy in patien…
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CLINICAL_TRIALS trial_result · 2025-03-17Clinical Trial Update: An Open-Label Study Following Oral Dosing of Seladelpar to Subjects With Primary Biliary Cholangitis (PBC) and Hepatic Impairment (HI) [Phase 1]
An open-label Phase 1 study evaluating oral dosing of seladelpar in adults with primary biliary cholangitis and hepatic impairment (compensa…
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CLINICAL_TRIALS trial_result · 2025-03-13Clinical Trial Update: Bacterial Infections in Patients with Cirrhosis in Argentina: Clinical and Microbiological Characteristics
A completed clinical trial update from Hospital Italiano de Buenos Aires describes the clinical and microbiological characteristics of bacte…
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CLINICAL_TRIALS trial_result · 2025-02-28Clinical Trial Update: Albumin for Management of Hypervolemic Hyponatremia (AlbuCAT) [Phase 2]
Phase 2 trial (AlbuCAT) evaluating albumin for management of hypervolemic hyponatremia in patients with cirrhosis has completed.
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CLINICAL_TRIALS trial_result · 2025-02-25Clinical Trial Update: Endoscopic Ultrasound-Guided Portosystemic Pressure Gradient Measurements [NA]
This is a completed clinical trial evaluating endoscopic ultrasound-guided portosystemic pressure gradient measurements. The study targets c…