Cirrhosis
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CLINICAL_TRIALS research · 2024-06-04Clinical Trial Update: Liver Cancer Disparities in American Indian and Alaska Native Persons [Phase 2]
This clinical trial update discusses a Phase 2 study investigating liver cancer disparities affecting American Indian and Alaska Native peop…
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CLINICAL_TRIALS research · 2024-06-04Clinical Trial Update: Evaluation of Cardiac Function in Acutely Decompensated Cirrhosis
A clinical trial update describing evaluation of cardiac function in patients with acutely decompensated cirrhosis; the study is currently a…
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CLINICAL_TRIALS research · 2024-05-20Clinical Trial Update: The Dual Impact of Cirrhosis on Transplantation for Hepatocellular Carcinoma：a Two-center Retrospective Cohort Study in China
A two-center retrospective cohort study from China examining how cirrhosis affects liver transplantation outcomes for hepatocellular carcino…
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CLINICAL_TRIALS research · 2024-05-07Clinical Trial Update: Clinical Value of the Developed Scoring Systems for Predicting Spontaneous Bacterial Peritonitis in Cirrhotic Ascites
A ClinicalTrials.gov entry describing a prospective study to evaluate scoring systems for predicting spontaneous bacterial peritonitis in pa…
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CLINICAL_TRIALS research · 2019-09-25Clinical Trial Update: Description of the Evolution of Plasma and Urinary Concentrations of Iohexol in a Cirrhotic Patient Population [Phase 4]
Phase 4 clinical trial observing plasma and urinary iohexol concentrations in patients with cirrhosis and renal impairment.
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CLINICAL_TRIALS research · 2019-05-14Clinical Trial Update: Propranolol, Carvedilol and Rosuvastatin in the Prevention of Variceal Bleeding in Cirrhotic Portal Hypertension [Phase 2, Phase 3]
A clinical trial update evaluating propranolol, carvedilol, and rosuvastatin for prevention of variceal bleeding in cirrhotic portal hyperte…
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CLINICAL_TRIALS research · 2019-02-01Clinical Trial Update: Vector Analysis of Body Composition in Hospitalized Cirrhotic Patients
An update on a clinical trial evaluating vector analysis of body composition in hospitalized patients with cirrhosis, with infection listed …
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CLINICAL_TRIALS research · 2018-06-06Clinical Trial Update: Bacterial Infections in Cirrhotic Patients With Acute Severe Liver Injury
This clinical trial update covers research on bacterial infections in cirrhotic patients with acute severe liver injury (NCT03204591). The c…
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CLINICAL_TRIALS research · 2018-04-25Clinical Trial Update: Multicenter Prospective Randomized Trial of the Effect of Rivaroxaban on Survival and Development of Complications of Portal Hypertension in Patients With Cirrhosis [Phase 3]
Phase 3 multicenter randomized trial evaluating rivaroxaban on survival and development of portal hypertension complications in patients wit…
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CLINICAL_TRIALS research · 2018-04-11Clinical Trial Update: Efficacity and Safety of Tranexamic Acid in Cirrhotic Patients Presenting With Acute Upper Gastrointestinal Bleeding [Phase 4]
A Phase 4 clinical trial evaluating the efficacy and safety of tranexamic acid in cirrhotic patients with acute upper gastrointestinal bleed…
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CLINICAL_TRIALS research · 2018-02-28Clinical Trial Update: To Compare Efficacy and Safety of Lactulose Versus Polyethylene Glycol for Treatment of Overt Hepatic Encephalopathy in Cirrhotics. [NA]
A clinical trial update comparing lactulose with polyethylene glycol for overt hepatic encephalopathy in patients with cirrhosis; current st…
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CLINICAL_TRIALS research · 2017-11-29Clinical Trial Update: On Demand Versus Protocol-guided Renal Replacement Therapy for Management of Stage 3 Acute Kidney Injury in Patients With Cirrhosis [NA]
This clinical trial update discusses comparing on-demand versus protocol-guided renal replacement therapy for stage 3 acute kidney injury in…
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CLINICAL_TRIALS research · 2017-11-07Clinical Trial Update: Relationship Between HbA1c and Chronic Glycemia in Patients With Cirrhosis
A completed clinical trial update examining the relationship between HbA1c and chronic glycemia in patients with cirrhosis and Type 2 diabet…
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CLINICAL_TRIALS research · 2017-08-23Clinical Trial Update: Endoscopic Band Ligation (EBL) Versus Endoscopic Band Ligation and Propranolol for the Prevention of Variceal Rebleeding [Phase 4]
This entry reports on a Phase 4 clinical trial comparing endoscopic band ligation alone versus endoscopic band ligation plus propranolol to …
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CLINICAL_TRIALS research · 2017-08-09Clinical Trial Update: HEMOCC Study. Hemostasis in Cirrhotic Children. [NA]
Clinical trial status update for the HEMOCC study (Hemostasis in Cirrhotic Children) indicates the trial has completed. It involves pediatri…
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CLINICAL_TRIALS research · 2017-06-15Clinical Trial Update: Refractory Ascitis Diagnosis by the Study of Labelled Albumin Pharmacokinetics [Phase 3]
Phase 3 clinical trial update on diagnosing refractory ascites in cirrhosis patients using labelled albumin pharmacokinetics; status is unkn…
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CLINICAL_TRIALS research · 2017-04-28Clinical Trial Update: Validation of Child-Turcotte-Pugh-Kumar (CTPK) Score in Predicting Short Term Mortality in Patients With Liver Cirrhosis
A clinical trial update evaluating the Child-Turcotte-Pugh-Kumar (CTPK) scoring system for predicting short-term mortality in patients with …
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CLINICAL_TRIALS research · 2017-04-17Clinical Trial Update: Glutamine Challenge as Predictor of Hepatic Encephalopathy After Transjugular Intrahepatic Portosystemic Shunt (TIPS)
This clinical trial update describes a terminated study investigating whether a glutamine challenge can predict hepatic encephalopathy after…
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CLINICAL_TRIALS research · 2017-01-23Clinical Trial Update: Validation in a Non-targeted Population of Single Ultrasound Doppler Signs of Liver Fibrosis [NA]
Clinical trial update on validating single ultrasound Doppler signs of liver fibrosis in a non-targeted population for cirrhosis; the curren…
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CLINICAL_TRIALS research · 2017-01-06Clinical Trial Update: Efficiency and Safety of Prophylactic Use of Antibiotics in Endoscopic Injection of Tissue Adhesive in Gastric Varices [NA]
This clinical trial update evaluates the efficiency and safety of prophylactic antibiotics during endoscopic injection of tissue adhesive fo…
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CLINICAL_TRIALS research · 2016-10-27Clinical Trial Update: Study of Accuracy of NGAL, a Renal Injury Biomarker, in Patients With Cirrhosis
This clinical trial update evaluates the accuracy of NGAL, a renal injury biomarker, in patients with cirrhosis, including those with acute …
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CLINICAL_TRIALS research · 2016-10-14Clinical Trial Update: Cirrhosis Readmission Telehealth Project [NA]
A Yale University-sponsored clinical trial on telehealth to reduce readmissions in cirrhosis has been terminated.
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CLINICAL_TRIALS research · 2016-10-12Clinical Trial Update: A RCT COMPARING LACTULOSE AND RIFAXIMIN ASSOCIATED WITH A VEGETABLE DIET IN THE PREVENTION OF POST-TIPS OVERT HEPATIC ENCEPHALOPATHY [Phase 1, Phase 2]
A Phase 1/2 randomized trial comparing lactulose and rifaximin (with a vegetable diet) to prevent post-TIPS hepatic encephalopathy in cirrho…
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CLINICAL_TRIALS research · 2016-09-02Clinical Trial Update: The Effect of Branched-chain Amino Acid on the Improvement of Serum Albumin Level in Cirrhotic Patients With Ascites [Phase 4]
Phase 4 clinical trial evaluating whether branched-chain amino acids can improve serum albumin levels in patients with cirrhosis and ascites…
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CLINICAL_TRIALS research · 2016-05-02Clinical Trial Update: Assessment of Coagulation Abnormalities in Acute on Chronic Liver Failure Patients Using Thromboelastography [Phase 4]
Phase 4 clinical trial update evaluating coagulation abnormalities in patients with acute-on-chronic liver failure using thromboelastography…