Thromboembolic Pulmonary Hypertension
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CLINICAL_TRIALS research · 2025-06-12Clinical Trial Update: Chronic Thromboembolic Disease Registry
A UC San Francisco-sponsored registry study on chronic thromboembolic disease and chronic thromboembolic pulmonary hypertension is currently…
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CLINICAL_TRIALS research · 2025-05-29Clinical Trial Update: Switching of Sildenafil to Riociguat in CTEPH Patients [Phase 4]
A Phase 4 clinical trial is evaluating switching chronic thromboembolic pulmonary hypertension patients from sildenafil to riociguat.
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CLINICAL_TRIALS research · 2025-05-15Clinical Trial Update: Effects of Pulmonary Rehabilitation on Quality of Life and Health in Pulmonary Arterial Hypertension Patients [NA]
A clinical trial is planned to assess the impact of pulmonary rehabilitation on quality of life and health in patients with pulmonary arteri…
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CLINICAL_TRIALS research · 2025-05-08Clinical Trial Update: TrEatment Approach in the Multimodal Era Registry
This clinical trial registry entry from the International CTEPH Association describes an active-not-recruiting registry study focused on tre…
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CLINICAL_TRIALS trial_result · 2025-05-07Clinical Trial Update: This Study Tests the Safety of Inhaled BAY1237592, How the Drug is Tolerated and How it Effects Patients With High Blood Pressure in the Arteries of the Lungs in the Two Different Disease Groups Pulmonary Arterial Hypertension (PAH) and Chronic Thromboembolic Pulmonary Hypertension (CTEPH) [Phase 1]
A Phase 1 trial evaluating the safety, tolerability, and preliminary effects of inhaled BAY1237592 in patients with pulmonary arterial hyper…
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CLINICAL_TRIALS research · 2025-04-30Clinical Trial Update: Riociguat-Discontinue Effects on Right HEART in CTEPH (RED-HEART) [Phase 3]
A Phase 3 clinical trial (RED-HEART) is evaluating riociguat for its effects on the right heart in chronic thromboembolic pulmonary hyperten…
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CLINICAL_TRIALS trial_result · 2025-04-27Clinical Trial Update: A Clinical Study to Investigate the Long-term Safety of the Drug Macitentan in Patients With Pulmonary Hypertension Who Were Previously Treated With Macitentan in Clinical Studies. [Phase 3]
Phase 3 long-term safety study of macitentan in patients with pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertens…
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CLINICAL_TRIALS trial_result · 2025-04-22Clinical Trial Update: A Study to Evaluate Efficacy and Safety of Macitentan 75 mg in Inoperable or Persistent/Recurrent Chronic Thromboembolic Pulmonary Hypertension [Phase 3]
A Phase 3 study evaluating macitentan 75 mg for inoperable or persistent/recurrent chronic thromboembolic pulmonary hypertension was termina…
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CLINICAL_TRIALS research · 2025-03-28Clinical Trial Update: Frailty, Physical Capacity and Lung Function in Postoperative Pulmonary Endarterectomy Patients
A clinical trial update evaluating frailty, physical capacity, and lung function in patients who recently underwent pulmonary endarterectomy…
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CLINICAL_TRIALS trial_result · 2025-02-03Clinical Trial Update: Bosentan Effects in Inoperable Forms of Chronic Thromboembolic Pulmonary Hypertension [Phase 3]
An update on a Phase 3 trial of bosentan for inoperable chronic thromboembolic pulmonary hypertension indicates the study has completed.
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: the Application of Cardiopulmonary Exercise Testing in Assessment Outcome of Patients With Pulmonary Hypertension
A clinical trial update indicates a study evaluating the use of cardiopulmonary exercise testing to assess outcomes in patients with pulmona…
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CLINICAL_TRIALS research · 2024-08-28Clinical Trial Update: Chinese PE Multimodality Imaging Artificial Intelligence Study
Clinical trial update for a Chinese multimodality imaging AI study focused on pulmonary embolism and chronic thromboembolic pulmonary hypert…
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CLINICAL_TRIALS trial_result · 2024-07-16Clinical Trial Update: Medication Reconciliation in Pulmonary Hypertension
A clinical trial evaluating medication reconciliation in pulmonary hypertension has completed, covering conditions such as pulmonary hyperte…
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CLINICAL_TRIALS trial_result · 2024-06-20Clinical Trial Update: The Effect of Oxygen Therapy on 6MWD in PAH and CTEPH Patients With Hypoxemia [Phase 2]
Phase 2 clinical trial update evaluating whether supplemental oxygen improves six-minute walk distance in hypoxemic patients with pulmonary …
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CLINICAL_TRIALS trial_result · 2024-05-17Clinical Trial Update: Right Atrial Fibrosis in Pulmonary Hypertension
A ClinicalTrials.gov update indicates a completed study on right atrial fibrosis in pulmonary hypertension, including chronic thromboembolic…
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CLINICAL_TRIALS trial_result · 2024-05-03Clinical Trial Update: Prevalence of Chronic Thromboembolic Pulmonary Hypertension After Acute Pulmonary Embolism : (Preva-CTEPH) [NA]
This entry summarizes the completed Preva-CTEPH clinical trial assessing the prevalence of chronic thromboembolic pulmonary hypertension aft…
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CLINICAL_TRIALS research · 2024-04-29Clinical Trial Update: BPA vs. PEA in CTEPH [NA]
Clinical trial comparing balloon pulmonary angioplasty versus pulmonary endarterectomy in chronic thromboembolic pulmonary hypertension is c…
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CLINICAL_TRIALS trial_result · 2024-04-02Clinical Trial Update: Balloon Pulmonary Angioplasty vs. Combined Approach With Pulmonary Artery Denervation in CTEPH: Effectiveness Comparison [Phase 2, Phase 3]
A clinical trial comparing balloon pulmonary angioplasty to a combined approach with pulmonary artery denervation in chronic thromboembolic …
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CLINICAL_TRIALS trial_result · 2023-10-05Clinical Trial Update: Clinical Trial to Investigate Safety and Efficacy of Edoxaban in Patients With CTEPH (KABUKI) [Phase 3]
Phase 3 trial assessing safety and efficacy of edoxaban in chronic thromboembolic pulmonary hypertension (CTEPH) has completed.
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CLINICAL_TRIALS trial_result · 2023-08-09Clinical Trial Update: A Study to Find Out if Selexipag is Effective and Safe in Patients With Chronic Thromboembolic Pulmonary Hypertension When the Disease is Inoperable or Persistent/Recurrent After Surgery and/or Interventional Treatment [Phase 3]
Phase 3 trial evaluating selexipag for chronic thromboembolic pulmonary hypertension in patients inoperable or with persistent/recurrent dis…
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CLINICAL_TRIALS trial_result · 2023-04-11Clinical Trial Update: Clinical Study to Assess the Safety, Tolerability and Efficacy of Macitentan in Subjects With Inoperable Chronic Thromboembolic Pulmonary Hypertension [Phase 2]
Phase 2 trial results evaluating the safety, tolerability, and efficacy of macitentan in adults with inoperable chronic thromboembolic pulmo…
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CLINICAL_TRIALS trial_result · 2021-08-10Clinical Trial Update: The Role of Matrix Metalloproteinase 2 and 9 Enzymes in Developing Chronic Thromboembolic Pulmonary Hypertension
A completed clinical trial examining the role of matrix metalloproteinase 2 and 9 in chronic thromboembolic pulmonary hypertension, with res…
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CLINICAL_TRIALS trial_result · 2021-06-22Clinical Trial Update: Riociguat in Patients With Operable CTEPH Prior to Pulmonary Endarterectomy (PEA Bridging Study) [Phase 2]
Phase 2 trial investigating riociguat as bridging therapy before pulmonary endarterectomy in operable CTEPH; the study status is terminated …
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CLINICAL_TRIALS trial_result · 2021-06-18Clinical Trial Update: A Clinical Study to Find Out if Macitentan is Effective and Safe in Japanese Patients With Chronic Thromboembolic Pulmonary Hypertension (CTEPH). [Phase 3]
A Phase 3 clinical trial evaluating macitentan for chronic thromboembolic pulmonary hypertension (CTEPH) in Japanese patients has been termi…
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CLINICAL_TRIALS trial_result · 2021-02-25Clinical Trial Update: CTEPH Identification an Standard Computerised Tomography Pulmonary Angiography in Pulmonary Embolism Patients
A completed clinical trial evaluating identification of chronic thromboembolic pulmonary hypertension (CTEPH) using standard computerized to…