Pain
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Sign up freeTop drugs studied for this disease
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FDA approval · 2017-05-23FDA Approved: BUPRENORPHINE — Supplemental Application (Sun Pharmaceutical Industries, Inc.)
FDA approved a supplemental application for buprenorphine by Sun Pharmaceutical Industries, Inc., through an ANDA supplement to modify or ad…
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FDA approval · 2017-05-23FDA Approved: BUPRENORPHINE — Supplemental Application (Rhodes Pharmaceuticals L.P.)
FDA approved a supplemental application for buprenorphine from Rhodes Pharmaceuticals L.P., indicating regulatory action on an existing prod…
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FDA approval · 2017-05-23FDA Approved: BUPRENORPHINE — Supplemental Application (Hikma Pharmaceuticals USA Inc.)
FDA approved Hikma Pharmaceuticals USA Inc.'s supplemental application for buprenorphine (generic), marking regulatory approval for the gene…
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FDA approval · 2017-05-19FDA Approved: MORPHINE SULFATE — Supplemental Application (Amneal Pharmaceuticals of New York LLC)
FDA approved a supplemental application for Morphine Sulfate by Amneal Pharmaceuticals of New York LLC under ANDA 200411, granting a supplem…
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CLINICAL_TRIALS trial_result · 2017-05-19Clinical Trial Update: Lidocaine and Ketamine Versus Standard Care on Acute and Chronic Pain [NA]
Clinical trial comparing lidocaine and ketamine to standard care for acute and chronic pain was terminated; results were posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-05-18Clinical Trial Update: SUNBURST (Success Using Neuromodulation With BURST) Study [NA]
Abbott Medical Devices completed the SUNBURST neuromodulation trial for chronic pain. Results were posted on May 18, 2017.
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CLINICAL_TRIALS trial_result · 2017-05-15Clinical Trial Update: Development of a Couple-based Mindfulness Intervention for Chronic Pain [NA]
This entry notes the completion of NCT02316288, a Wayne State University study evaluating a couple-based mindfulness intervention for chroni…
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CLINICAL_TRIALS trial_result · 2017-05-12Clinical Trial Update: Efficacy of Premixed Nitrous Oxide and Oxygen in Patient With Out-of-hospital Moderate Acute Pain [Phase 4]
The update reports on the efficacy of a premixed nitrous oxide and oxygen gas for treating out-of-hospital moderate acute pain in a Phase 4 …
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CLINICAL_TRIALS trial_result · 2017-05-12Clinical Trial Update: A Randomized, Double-blind Comparison of Morphine and Sufentanil for Prehospital Traumatic Severe Acute Pain [Phase 3]
A Phase 3 randomized, double-blind trial compares morphine and sufentanil for prehospital management of traumatic severe acute pain. The stu…
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CLINICAL_TRIALS trial_result · 2017-05-11Clinical Trial Update: Determination of the 90% Effective Dose of a Sufentanil Bolus in Analgesia During Lateral Decubitus of Mechanically Ventilated Patients [Phase 4]
A Phase 4 trial reports the ED90 dose of sufentanil bolus for analgesia in mechanically ventilated patients in the lateral decubitus positio…
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CLINICAL_TRIALS research · 2017-05-11Clinical Trial Update: An Internet-Delivered Pain Management Programme for Spinal Cord Injury Pain [NA]
This document provides a status update on a clinical trial of an internet-delivered pain management program for pain associated with spinal …
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CLINICAL_TRIALS trial_result · 2017-05-10Clinical Trial Update: Ultrasound-guided Supraclavicular Brachial Plexus Blockade [NA]
This clinical trial update notes termination of a study evaluating ultrasound-guided supraclavicular brachial plexus blockade for pain, with…
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CLINICAL_TRIALS trial_result · 2017-05-05Clinical Trial Update: Evaluation of a Health Plan Initiative to Mitigate Chronic Opioid Therapy Risks
A completed clinical trial evaluated a health plan–level initiative to mitigate risks from chronic opioid therapy, with results posted in 20…
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CLINICAL_TRIALS trial_result · 2017-05-02Clinical Trial Update: Preoperative Catastrophizing Predicts Pain Outcome After Shoulder, Knee and Hip Arthroplasty
This completed clinical trial reports that higher preoperative catastrophizing is associated with worse postoperative pain after shoulder, k…
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CLINICAL_TRIALS trial_result · 2017-04-28Clinical Trial Update: The Effect of Intraoperative Ketamine on Opioid Consumption and Pain After Spine Surgery in Opioid-dependent Patients [Phase 4]
A Phase 4 trial investigates whether intraoperative ketamine reduces opioid consumption and postoperative pain after spine surgery in opioid…
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CLINICAL_TRIALS withdrawal · 2017-04-26Clinical Trial Update: The Efficacy of CALPXT96™in Improving Sleep Quality in Patients With Chronic Non-cancer Pain [Phase 3]
A Phase 3 trial evaluating CALPXT96 for improving sleep quality in patients with chronic non-cancer pain has been withdrawn.
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CLINICAL_TRIALS research · 2017-04-24Clinical Trial Update: fMRI and Central Sensitization in Chronic Knee Osteoarthritis. A Pre and Post TKR Study
Clinical trial update describing a pre- and post-total knee replacement study examining functional MRI and central sensitization in chronic …
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CLINICAL_TRIALS trial_result · 2017-04-24Clinical Trial Update: The Clinical Evaluation of Implantable Pump System For Safety And Delivery Accuracy In Patients Requiring Intrathecal Administration Of Morphine Sulfate For Chronic Pain [Phase 2, Phase 3]
This update reports on a Phase 2/Phase 3 trial evaluating an implantable pump system for delivering intrathecal morphine sulfate in chronic …
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CLINICAL_TRIALS trial_result · 2017-04-21Clinical Trial Update: Accelerometer Based Objective Clinical Outcomes of Spinal Cord Stimulation (SCS) and Peripheral Nerve Stimulation (PNS)
The clinical trial evaluating accelerometer-based objective outcomes for spinal cord stimulation (SCS) and peripheral nerve stimulation (PNS…
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CLINICAL_TRIALS trial_result · 2017-04-21Clinical Trial Update: Chronic Pain and Assessment of Sleep [NA]
This clinical trial update concerns a study on chronic pain and sleep assessment sponsored by the University of Aberdeen. The trial status i…
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FDA approval · 2017-04-20FDA Approved: PENTAZOCINE HYDROCHLORIDE AND NALOXONE HYDROCHLORIDE — Supplemental Application (Lupin Pharmaceuticals,Inc.)
FDA approved Lupin's supplemental application for Pentazocine Hydrochloride and Naloxone Hydrochloride, updating the product's approval unde…
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CLINICAL_TRIALS trial_result · 2017-04-20Clinical Trial Update: The Effects of Water Temperature on the Cold Pressor Test
A completed Georgetown University clinical trial evaluating how different water temperatures influence responses on the cold pressor test in…
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CLINICAL_TRIALS trial_result · 2017-04-20Clinical Trial Update: Enhancing Management of Chronic Pain and Symptoms Among Women Treated for Breast Cancer (Lymph-Flow) [NA]
A completed clinical trial update on managing chronic pain and related symptoms in women treated for breast cancer, under the Lymph-Flow stu…
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CLINICAL_TRIALS trial_result · 2017-04-14Clinical Trial Update: Pain Relief in the Emergency Department Waiting Room: a Prevalence Study
A completed observational study evaluating how common pain relief is in patients in the emergency department waiting room.
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FDA approval · 2017-04-11FDA Approved: HYDROCODONE BITARTRATE AND ACETAMINOPHEN — Supplemental Application (Rhodes Pharmaceuticals L.P.)
FDA approved a supplemental application for Hydrocodone Bitartrate and Acetaminophen from Rhodes Pharmaceuticals L.P., expanding the approve…