Chronic Obstructive Pulmonary Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS withdrawal · 2018-03-08Clinical Trial Update: Evaluating the Clinical Effectiveness of 3D Printing for a Patient-specific Silicone Stent Airway Implant [NA]
The clinical trial evaluating 3D-printed silicone airway stent for COPD and emphysema has been withdrawn.
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CLINICAL_TRIALS trial_result · 2018-03-07Clinical Trial Update: Low Load, High-repetitive Elastic Band Resistance Training in COPD [NA]
A completed clinical trial evaluating low-load, high-repetition elastic band resistance training in chronic obstructive pulmonary disease pa…
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CLINICAL_TRIALS trial_result · 2018-03-07Clinical Trial Update: Using NT-proBNP to Detect Chronic Heart Failure in Patients With Chronic Obstructive Pulmonary Disease
The clinical trial evaluated NT-proBNP as a diagnostic biomarker for chronic heart failure in patients with chronic obstructive pulmonary di…
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CLINICAL_TRIALS trial_result · 2018-03-07Clinical Trial Update: Brain During Effort : Effects of Hypoxia With Respiratory Patients [NA]
Completed study update on brain activity during effort under hypoxia in patients with COPD and obstructive sleep apnea.
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FDA label_change · 2018-03-02FDA Approved: FLUTICASONE PROPIONATE AND SALMETEROL — Supplemental Application (Teva Pharmaceuticals USA, Inc.)
FDA approved a supplemental application for the inhaled combination product fluticasone propionate and salmeterol, resulting in changes to i…
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CLINICAL_TRIALS trial_result · 2018-03-01Clinical Trial Update: Hypobaric Flight Simulation in COPD Patients [NA]
Completed clinical trial investigating hypobaric flight simulation in COPD patients.
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CLINICAL_TRIALS research · 2018-02-28Clinical Trial Update: Inhaler Technique in Elderly Patients: Impact on Disease Exacerbations [Phase 4]
Phase 4 clinical trial update examining whether inhaler technique in elderly patients affects asthma and COPD exacerbations. The current stu…
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CLINICAL_TRIALS trial_result · 2018-02-28Clinical Trial Update: Feasibility and Effect of a Follow up Tele-rehabilitation Program for Chronic Obstructive Lung Disease vs. Standard Follow up [NA]
A clinical trial from the University of Aarhus assesses the feasibility and effects of a tele-rehabilitation follow-up program for chronic o…
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CLINICAL_TRIALS trial_result · 2018-02-28Clinical Trial Update: Evaluate Efficacy of Respiratory Rehabilitation Personalized Mobile Services for Respiratory Diseases [NA]
Completed clinical trial evaluating the efficacy of personalized mobile respiratory rehabilitation services for COPD and lung cancer.
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CLINICAL_TRIALS trial_result · 2018-02-27Clinical Trial Update: Physiological Study of Minimally Invasive ECCO2R in Exacerbations of COPD Requiring Invasive Mechanical Ventilation [NA]
The document reports the completion of a physiological study evaluating minimally invasive extracorporeal CO2 removal (ECCO2R) in COPD patie…
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CLINICAL_TRIALS research · 2018-02-27Clinical Trial Update: Determinants of Onset and Progression of COPD in Young Adults
This clinical trial update discusses factors influencing the onset and progression of chronic obstructive pulmonary disease in young adults.
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CLINICAL_TRIALS trial_result · 2018-02-22Clinical Trial Update: A Study To Assess The Safety And Tolerability Of GW642444 In Subjects With Chronic Obstructive Pulmonary Disease (COPD) [Phase 2]
A Phase 2 trial evaluating the safety and tolerability of GW642444 in Chronic Obstructive Pulmonary Disease has completed with results poste…
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CLINICAL_TRIALS withdrawal · 2018-02-22Clinical Trial Update: Magnesium Sulfate to Prevent Hospitalisation of Acute Exacerbations of Chronic Obstructive Pulmonary Disease [Phase 4]
A Phase 4 trial evaluating magnesium sulfate to prevent hospitalization during acute exacerbations of chronic obstructive pulmonary disease …
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CLINICAL_TRIALS trial_result · 2018-02-19Clinical Trial Update: A Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD7594 Inhaled Formulation in Healthy Japanese Men [Phase 1]
Phase 1 study assessing safety, tolerability, and pharmacokinetics of AZD7594 inhaled formulation in healthy Japanese men; completed with re…
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CLINICAL_TRIALS trial_result · 2018-02-09Clinical Trial Update: Effects of Traditional Chinese Medicine on AECOPD Patients [Phase 3]
Phase 3 trial investigating effects of Traditional Chinese Medicine in patients with acute exacerbation of chronic obstructive pulmonary dis…
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CLINICAL_TRIALS trial_result · 2018-02-08Clinical Trial Update: A Dose Ascending, Study To Examine The Safety, Tolerability, Pharmacokinetics And Pharmacodynamics Of GSK233705B. [Phase 2]
A Phase 2 dose-ascending study evaluating the safety, tolerability, pharmacokinetics, and pharmacodynamics of GSK233705B in chronic obstruct…
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EMA withdrawal · 2018-02-08EMA Withdrawn: Libertek (roflumilast) — AstraZeneca AB
Libertek (roflumilast) has been withdrawn from the market by AstraZeneca AB.
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CLINICAL_TRIALS trial_result · 2018-02-07Clinical Trial Update: Formoterol Dose Ranging Study (ACHIEVE Duaklir USA Phase IIb) [Phase 2]
Phase IIb dose-ranging study in COPD completed; results posted in 2018 for formoterol in ACHIEVE Duaklir USA program.
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EMA withdrawal · 2018-02-06EMA Withdrawn: Daliresp (roflumilast) — AstraZeneca AB
The EMA document indicates that Daliresp (roflumilast) has been withdrawn from the market in the EU.
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CLINICAL_TRIALS trial_result · 2018-01-26Clinical Trial Update: β2-agonist Versus Ipratropium Bromide Associated With β2-agonists in Chronic Obstructive Pulmonary Disease Exacerbation [Phase 3]
Phase 3 trial comparing a β2-agonist versus ipratropium bromide in COPD exacerbation completed.
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CLINICAL_TRIALS trial_result · 2018-01-25Clinical Trial Update: A Dose-Range Finding Study of SUN-101 in Subjects With Moderate to Severe COPD [Phase 2]
Phase 2 dose-range finding study of SUN-101 in adults with moderate to severe COPD was completed and results were posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-01-25Clinical Trial Update: Effect of Inhaled Steroids on Gene Expression in the Lungs - 2 [Phase 4]
Phase 4 trial investigating the effect of inhaled steroids on gene expression in the lungs for chronic obstructive pulmonary disease; study …
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FDA label_change · 2018-01-23FDA Approved: DALIRESP — Supplemental Application (AstraZeneca Pharmaceuticals LP)
FDA approved a supplemental application for DALIRESP (roflumilast) from AstraZeneca Pharmaceuticals LP, updating labeling.
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CLINICAL_TRIALS trial_result · 2018-01-23Clinical Trial Update: Study to Assess the Efficacy and Safety of Three Doses of PT001 in Japanese Subjects With Moderate to Severe COPD [Phase 2]
Phase 2 trial evaluating three doses of PT001 in Japanese subjects with COPD has completed.
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CLINICAL_TRIALS trial_result · 2018-01-04Clinical Trial Update: Randomised, Double-Blind, Placebo-Controlled, Parallel-Group, Multi-centre, Dose Ranging Study to Evaluate the Efficacy and Safety of Losmapimod Tablets Administered Twice Daily Compared With Placebo for 24 Weeks in Adult Subjects With Chronic Obstructive Pulmonary Disease (COPD). [Phase 2]
A Phase 2 randomized, double-blind study evaluated the efficacy and safety of losmapimod tablets vs placebo over 24 weeks in adults with chr…