Chronic Obstructive Pulmonary Disease

CLINICAL_TRIALS trial_result · 2018-11-16

Clinical Trial Update: Home Non Invasive Ventilation (NIV) Treatment for COPD-patients After a NIV-treated Exacerbation [Phase 4]

Phase 4 clinical trial update on home noninvasive ventilation for COPD patients after an NIV-treated exacerbation.

FDA approval · 2018-11-09

FDA Approved: YUPELRI — Original Application (Viatris Specialty LLC)

FDA approved YUPELRI (revefenacin) from Viatris Specialty LLC as an original NDA approval for chronic obstructive pulmonary disease.

FDA approval · 2018-11-09

FDA Approved: TUDORZA PRESSAIR — Supplemental Application (Covis Pharma US, Inc)

FDA approved a supplemental application for Tudorza Pressair (aclidinium bromide) submitted by Covis Pharma US, Inc.

CLINICAL_TRIALS trial_result · 2018-11-09

Clinical Trial Update: AMPLIFY - D6571C00001 Duaklir USA Phase III Study [Phase 3]

Phase 3 study AMPLIFY (D6571C00001) for Duaklir in chronic obstructive pulmonary disease has completed with results posted.

CLINICAL_TRIALS trial_result · 2018-11-08

Clinical Trial Update: Two-part Safety, Tolerability, Pharmacodynamic and -Kinetic Study of Inhaled AZD8871 in Asthmatic and COPD Subjects [Phase 1]

Phase 1 trial update evaluating safety, tolerability, pharmacodynamics, and pharmacokinetics of inhaled AZD8871 in asthmatic and COPD subjec…

FDA approval · 2018-11-05

FDA Approved: LEVALBUTEROL INHALATION SOLUTION — Original Application (Sun Pharmaceutical Industries, Inc.)

FDA approves Sun Pharmaceutical's levalbuterol inhalation solution as an original generic application. It is indicated for relief of broncho…

CLINICAL_TRIALS trial_result · 2018-10-30

Clinical Trial Update: Differentiating the Effects of Substance P and Beta-endorphin [NA]

Clinical trial completed evaluating differentiation of Substance P and Beta-endorphin effects in chronic obstructive pulmonary disease; resu…

CLINICAL_TRIALS trial_result · 2018-10-24

Clinical Trial Update: A Study to Show That Flutiform is Well Tolerated and Effective in the Treatment of COPD [Phase 3]

Phase 3 trial update indicating Flutiform is well tolerated and effective in chronic obstructive pulmonary disease.

CLINICAL_TRIALS trial_result · 2018-10-19

Clinical Trial Update: Airway Clearance for Prevention of Chronic Obstructive Pulmonary Disease (COPD) Exacerbation [Phase 4]

Phase 4 clinical trial updates airway clearance for COPD prevention; study completed with posted results.

CLINICAL_TRIALS trial_result · 2018-10-16

Clinical Trial Update: A Phase II, Study To Evaluate The Efficacy And Safety Of PH-797804 In Adults With Moderate To Severe Chronic Obstructive Pulmonary Disease (COPD). [Phase 2]

Phase II study evaluating efficacy and safety of PH-797804 in adults with moderate to severe COPD has completed.

CLINICAL_TRIALS research · 2018-10-15

Clinical Trial Update: Assessment of Physical Functioning and Handling of Spiolto® Respimat® in Patients With Chronic Obstructive Pulmonary Disease (COPD) Requiring Long-acting Dual Bronchodilation in Routine Clinical Practice

A completed clinical trial evaluating the physical functioning and handling of Spiolto Respimat in COPD patients on long-acting dual broncho…

CLINICAL_TRIALS trial_result · 2018-10-11

Clinical Trial Update: Vibratory PEP Device and Hospital Length of Stay for Acute Exacerbation of COPD [NA]

Clinical trial update evaluating a vibratory PEP device for acute COPD exacerbation; results posted after completion. No specific efficacy d…

CLINICAL_TRIALS trial_result · 2018-10-10

Clinical Trial Update: A Study Comparing the Efficacy, Safety and Tolerability of Fixed Dose Combination (FDC) of FF/UMEC/VI With the FDC of FF/VI and UMEC/VI; Administered Once-daily Via a Dry Powder Inhaler (DPI) in Subjects With Chronic Obstructive Pulmonary Disease (COPD) [Phase 3]

Phase 3 trial comparing fixed-dose combination inhalers for COPD; results completed with posted results in 2018.

CLINICAL_TRIALS trial_result · 2018-10-10

Clinical Trial Update: Doxycycline for COPD in HIV-Infected Patients [NA]

A completed clinical trial assessing doxycycline for COPD in HIV-infected patients; results posted in 2018.

CLINICAL_TRIALS trial_result · 2018-10-09

Clinical Trial Update: Effect of Aclidinium/Formoterol on Lung Hyperinflation, Exercise Capacity and Physical Activity in Moderate to Severe COPD Patients [Phase 4]

Phase 4 trial evaluating the impact of aclidinium/formoterol on lung hyperinflation, exercise capacity, and physical activity in moderate to…

FDA approval · 2018-10-05

FDA Approved: STIOLTO RESPIMAT — Supplemental Application (Boehringer Ingelheim Pharmaceuticals, Inc.)

The FDA approved a supplemental application for STIOLTO RESPIMAT (tiotropium bromide and olodaterol) submitted by Boehringer Ingelheim Pharm…

FDA approval · 2018-10-03

FDA Approved: ROFLUMILAST — Original Application (Jubilant Cadista Pharmaceuticals Inc.)

FDA approved Jubilant Cadista's original application for roflumilast, a PDE-4 inhibitor, to reduce the risk of COPD exacerbations in adults …

CLINICAL_TRIALS trial_result · 2018-09-26

Clinical Trial Update: Comparison of Dobutamine and Regadenoson Stress Cardiac Magnetic Resonance (MR) [EARLY_Phase 1]

Early-phase clinical trial comparing dobutamine and regadenoson for stress cardiac MR; the study is terminated with results posted in 2018.

CLINICAL_TRIALS trial_result · 2018-09-14

Clinical Trial Update: Study to Determine the Amount of Glycopyrrolate Absorbed in the Lungs After Taking the Medicine With a eFlow Nebulizer and Seebri® Breezhaler® With and Without Activated Charcoal in Subjects With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD). [Phase 1]

Phase 1 trial updating the absorption of glycopyrrolate in the lungs when administered with eFlow nebulizer and Seebri Breezhaler, with and …

CLINICAL_TRIALS trial_result · 2018-09-05

Clinical Trial Update: Azithromycin for Acute Exacerbations Requiring Hospitalization [Phase 3]

A Phase 3 trial of azithromycin for acute exacerbations requiring hospitalization in COPD was terminated.